Cannabinoid concentrations in hair from documented cannabis users

Fifty-three head hair specimens were collected from 38 males with a history of cannabis use documented by questionnaire, urinalysis and controlled, double blind administration of delta9-tetrahydrocannabinol (THC) in an institutional review board approved protocol. The subjects completed a questionnaire indicating daily cannabis use (N=18) or non-daily use, i.e. one to five cannabis cigarettes per week (N=20). Drug use was also documented by a positive cannabinoid urinalysis, a hair specimen was collected from each subject and they were admitted to a closed research unit. Additional hair specimens were collected following smoking of two 2.7% THC cigarettes (N=13) or multiple oral doses totaling 116 mg THC (N=2). Cannabinoid concentrations in all hair specimens were determined by ELISA and GCMSMS. Pre- and post-dose detection rates did not differ statistically, therefore, all 53 specimens were considered as one group for further comparisons. Nineteen specimens (36%) had no detectable THC or 11-nor-9-carboxy-THC (THCCOOH) at the GCMSMS limits of quantification (LOQ) of 1.0 and 0.1 pg/mg hair, respectively. Two specimens (3.8%) had measurable THC only, 14 (26%) THCCOOH only, and 18 (34%) both cannabinoids. Detection rates were significantly different (p<0.05, Fishers' exact test) between daily cannabis users (85%) and non-daily users (52%). There was no difference in detection rates between African-American and Caucasian subjects (p>0.3, Fisher's exact test). For specimens with detectable cannabinoids, concentrations ranged from 3.4 to >100 pg THC/mg and 0.10 to 7.3 pg THCCOOH/mg hair. THC and THCCOOH concentrations were positively correlated (r=0.38, p<0.01, Pearson's product moment correlation). Using an immunoassay cutoff concentration of 5 pg THC equiv./mg hair, 83% of specimens that screened positive were confirmed by GCMSMS at a cutoff concentration of 0.1 pg THCCOOH/mg hair.     

Arrested development? Sub-Saharan Africa in the stratified world economy 1965–2015

ABSTRACT

The central concern of this paper is with Sub-Saharan Africa's (SSA) standing in the stratified world economy. Country standings are determined for the period 1965 through 2015, based on the Arrighi and Drangel method of calculating world-system position. We find that the region as a whole remained in the bottom of the global economic hierarchy and was particularly sensitive to macroeconomic-historical changes and pressures. Of note too is the clear link between the SSA countries that are performing well in the semiperiphery of the global economic hierarchy and those with a concentration of natural resources.     

The Proprietary Foundations of Corporate Law

Recent work in both the theory of the firm and of corporatelaw has called into question the appropriateness of analysingcorporate law as ‘merely’ a set of standard formcontracts. This article develops these ideas by focusing onproperty law's role in underpinning corporate enterprise. Rightsto control assets are a significant mechanism of governancein the firm. However, their use in this way predicates somearrangement for stipulating which parties will have controlunder which circumstances. It is argued that ‘propertyrules’—a category whose scope is determined functionally—protectthe entitlements of parties to such sharing arrangements againsteach other's opportunistic attempts to grant conflicting entitlementsto third parties. At the same time, the legal system uses arange of strategies to minimize the costs such protection imposeson third parties. The choice of strategy significantly affectsco-owners’ freedom to customize their control-sharingarrangements. This theory is applied to give an account of the‘proprietary foundations’ of corporate law, whichhas significant implications for the way in which the subject'sfunctions are understood and evaluated.     

Women in the American Society for Public Administration: Another Decade of Progress But Still a Way to Go

During ASPA's first fifty years (1939–1989), the role of women in the Society evolved from virtual invisibility, to token representation, to major participation. In the 1990s, women's role in ASPA continued to expand. They achieved just about full partnership with male colleagues in the organization's governance and they increased their contributions to ASPA's efforts to support the improvement of theory and practice in public administration through research and scholarship. However, women have not yet achieved parity with their male colleagues in scholarly output. For women to achieve full equality with men in ASPA, they must be better represented in contributions to literature and knowledge in the profession.     

Childbearers as rights-bearers: feminist discourse on the rights of aboriginal and non-aboriginal mothers in Australia, 1920–50

Abstract

In the post-suffrage era in Australia, feminists invoked maternalist arguments in support of the idea that mothers were political subjects with rights and they extended their campaigns to press for recognition of the rights of Aboriginal women. This article examines the claim made by post-suffrage feminists that ‘the common status of motherhood’ entailed a range of social, economic and civil rights. They argued in Royal Commissions, election campaigns, and the press that all mothers, working class and middle class, Aboriginal and non-Aboriginal, who wished to retain the custody of their children should have the legal right and economic ability to do so. In New South Wales the campaign culminated in the staging of a play called Whose Child? This article explores some of the tensions between Women's claims as mothers and as independent citizens and the difficulties encountered when feminists attempted to have mothers' rights defined as human rights in the Universal Declaration of Human Rights in 1948.     

Kay Daniels as feminist historian

Abstract

While spending the better part of two academic years out of her home country, the USA, the author became increasingly perplexed by the current emphasis on poststructural theory in the writing of women's history. She says this because such theory may not only isolate this highly successful new subfield from the ongoing Second Women's Movement in the United States and from history teachers trying to integrate material on women into their classes, but most sadly, isolate American historians of women from their counterparts in Eastern European and Third World countries who are only beginning to write about their past.