Near Infrared Spectroscopy Detection and Quantification of Herbal Medicines Adulterated with Sibutramine

There is an increasing demand for herbal medicines in weight loss treatment. Some synthetic chemicals, such as sibutramine (SB), have been detected as adulterants in herbal formulations. In this study, two strategies using near infrared (NIR) spectroscopy have been developed to evaluate potential adulteration of herbal medicines with SB: a qualitative screening approach and a quantitative methodology based on multivariate calibration. Samples were composed by products commercialized as herbal medicines, as well as by laboratory adulterated samples. Spectra were obtained in the range of 14,000–4000 per cm. Using PLS‐DA, a correct classification of 100% was achieved for the external validation set. In the quantitative approach, the root mean squares error of prediction (RMSEP), for both PLS and MLR models, was 0.2%w/w. The results prove the potential of NIR spectroscopy and multivariate calibration in quantifying sibutramine in adulterated herbal medicines samples.     

Antipoverty Transfers and Labour Market Outcomes: Regression Discontinuity Design Findings

The article estimates the impact of Familias en Acción, a human development conditional cash transfer programme, on adult labour market outcomes in urban areas in Colombia. Relying on a regression discontinuity design and a large panel dataset, the article finds significant, largely positive, but heterogeneous programme effects on labour market outcomes. The findings suggest that antipoverty transfers enable a re-allocation of household productive resources among participant households.     

Genetic analysis of the populations from Northern and Mesopotamian provinces of Argentina by means of 15 autosomal STRs

The allele frequencies for the 15 short tandem repeats included in the Power Plex-16 kit (Promega Corp., Madison, WI, USA) were determined in a sample of 429 unrelated individuals from five provinces of the Northern and Northeastern regions of Argentina. Three Northern provinces including Salta, Formosa and Chaco and two within the region surrounded by the Paraná and Uruguay Rivers commonly known as the Argentine Mesopotamia, including Misiones and Corrientes. Since in this region Entre Ríos Province is also present, previously published results were used for comparison. The calculated parameters: polymorphism information content (PIC); discrimination power (DP); matching probability (MP); typical paternity index (TPI) and power of exclusion (PE) showed Penta E to be the most valuable marker from the studied sample set. All loci met Hardy–Weinberg expectations using the Bonferroni correction for the number of loci analyzed, except D3S1358 in Salta and THO1 in Formosa provinces. Population differentiation test revealed that the Salta population sample data denoted significant differences for various loci when compared with the other province information presented here in, as well as with other published data sets.     

Fishing from the same schools: Parliamentary recruitment and consociationalism in the first and second Italian republics

This article addresses several issues surrounding the politics of flexibility in Spain. First, it argues that the strategic role of trade unions develop and condition public policies on labour market reform by couching their strategies in terms of the post‐war labour market strategies and structures of the state, especially as governments attempt to move away from established forms of fordist regulation. Hence, second, a broader political and historical perspective is required that understands the complex political dynamics of state‐labour relationships and their structuring over time. The state's role and its labour market presence becomes itself the object of distinct political interventions and calculations by unions, governments and employers. Any discussion of a ‘post‐fordist’ state, determined to increase the flexibility of the labour market, must look at the complex and difficult ‘transitional’ process.     

Trust in elections,vote buying,and turnout in Latin America

Although national elections in Latin America are now described as reasonably free and fair by international observations teams, electoral processes are still affected by a series of malpractices (unequal access to the media and public resources, registration problems, vote buying). These irregularities negatively affect citizens' trust in elections. In this paper, we analyze the consequences of low trust in elections and exposure to vote buying practices on electoral participation in Latin America. Using data from the 2010 wave of LAPOP surveys, we find that perceiving that the election is unfair reduces the willingness to participate in national elections, but receiving material incentives during the campaign has the opposite effect of increasing electoral participation. We also show that the effect of trust in elections on turnout is larger in countries where voting is not mandatory.