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951.
In continuation of previous light microscope investigations the question has been raised whether the criteria determined for vital muscle damage using light microscopy, could be verified and perhaps extended for the ultrastructural region. In addition to existing human pathological material taken early post mortem, muscle tissue obtained from animal experiments was also examined. The evaluation concentrated on the muscle cells, the cell organelles and the contractile apparatus. An evaluation of semi-thin-sections was carried out in parallel. The following reaction patterns could be defined as vital reactions: hypercontraction bands, zones of rupture in narrow topological relationship to organelle changes, microstructure changes with disintegration of the fibre structure, subsarcolemmic and interfibrillary oedema, decomposition of the sarcolemma. The earliest vital reactions were detectable after only a few minutes survival time. The comparison between the results of animal experiments and human pathology and the application of the results to forensic pathology will be discussed. 相似文献
952.
Adult male Wistar rats were treated with either 0.1 or 3 mg/kg body weight X day of digoxin for five days, then killed and stored at 4 degrees C for 12 h in an attempt to mimic the normal preautopsy procedures in our hospital. In rats treated with 0.1 mg/kg body weight X day, the antemortem serum digoxin concentrations (SDC) were 1.1 +/- 0.4 ng/mL while the 12-h postmortem concentration was markedly increased (16.3 +/- 5.9 ng/mL) (P less than 0.01). In rats treated with 3 mg/kg body weight X day, SDC was not changed significantly (11.2 +/- 4.8 ng/mL antemortem and 13.3 +/- 6 ng/mL postmortem). Postmortem redistribution of digoxin was assessed by injection of 125I-labelled digoxin with or without pretreatment with the unlabelled drug. The results indicate that after death passive redistribution of digoxin may take place. When the SDC are within the therapeutic or low toxic range, digoxin may reenter the blood. High antemortem serum concentrations of digoxin may prevent such passive redistribution. Therefore, antemortem digoxin intoxication cannot be reliably inferred on the basis of high postmortem levels of the drug. Digoxin intoxication can be ruled out when postmortem SDC remain within the therapeutic range. The above changes cast doubt on some of the forensic and cardiologic literature, which has in the past been based on incorrect assumptions concerning postmortem behavior of digoxin. 相似文献
953.
Baby K: Medical Futility and the Free Exercise of Religion 总被引:3,自引:0,他引:3
Stephen G. Post 《The Journal of law, medicine & ethics》1995,23(1):20-26
954.
955.
The positioning and magnification of faces and skulls for photographic superimposition 总被引:1,自引:0,他引:1
G J Maat 《Forensic science international》1989,41(3):225-235
In the identification of persons living or dead, or of skulls, the technique of photographic superimposition of laboratory images on existing original portraits has frequently been used. The applicability of the technique and the confidence in the results have always depended very much on the professional acceptance and experience of forensic specialists. Defined preconditions, improved methods and clear-cut directions on how to posture the head or the skull and how to magnify its photographic laboratory image, not only help to standardize and simplify procedures, but also increase the accuracy and credibility of the resulting diagnoses. A systematic approach with standard photographic equipment is presented. The validity of the results is discussed. 相似文献
956.
Two rapid and reliable electrophoretic techniques for PGM1 and EsD typing on ultrathin polyacrylamide gels are described. They have been based on non-equilibrium pH gradient electrophoresis and on the addition of chemical spacers (EPPS for PGM1 and HEPES for EsD) to the gel mixture. 相似文献
957.
National estimates of time trends and age trends in self-reported illegal behavior in the United States are compared with corresponding figures for arrests. The self-report data are from Monitoring the Future, an annual national survey of high school seniors. The analysis of time trends covers 1975 through 1985 for a sample of over 3,000 respondents per year, studied at a constant age. The analysis of age trends covers ages 17 through 23 for samples of 300 to 1,200 per year. Both self-report and arrest measures reveal substantial declines in illegal behavior throughout this age span, with the exception of arrests for assault. Both methods also indicate that rates of assault increased from 1975 through 1985, a finding that has not previously been reported. Time trends for other offenses were erratic. 相似文献
958.
J A Silva G B Leong R Weinstock C L Boyer 《The Bulletin of the American Academy of Psychiatry and the Law》1989,17(1):5-14
This article discusses Capgras syndrome and its association with harmful and potentially harmful behaviors. Phenomenological and psychodynamic analysis of a series of cases will highlight danger signals that may be present in Capgras patients. 相似文献
959.
A method is described for the determination of glyoxalase I phenotypes in liquid blood and dry bloodstains. The frequencies of glyoxalase I phenotypes in various populations of S.E. England are included. 相似文献
960.
Equipment for annealing casework sized glass particles is described. Investigations were carried out using a simple muffle furnace, a temperature programmed furnace and a metal sample holder. Because they produced a uniform and reproducible thermal environment, best results were obtained from a combination of the temperature programmed furnace and the metal sample holder. Refractive index changes for window and toughened glass specimens were investigated and a simple, reproducible annealing routine for casework was devised. 相似文献