The determination of benzodiazepines in biological objects on the Milichrome microcolumn liquid chromatograph]

1,4-benzodiazepines and benzophenols, the products of their hydrolytic cleavage, were measured by high-pressure liquid chromatography in expert material (stomach, liver, intestine, kidney samples). Milichrome microcolumn liquid chromatograph, designs 1 and 2, was employed, with a chromatography column packed with Separon C18 (5 microns) sorbent. A mixture of (NH4)2HPO4 (0.05 M) and acetonitryl in volume ratio 65:35 was used as the mobile phase in native compound analysis and that in volume ratio 45:55 for benzophenols and medazepam separation. The external standard method was used for quantitative estimation.     

The use of immunoenzyme analysis for determining ABH antigens in traces of saliva and sperm]

The authors suggest a simple sensitive technique for enzyme immunoassay (EIA) of ABH antigens in saliva and semen. A two-staged dot blot solid-phase EIA on nitrocellulose membranes was employed with anti-ABH monoclonal antibodies obtained in immunization of mice with human red cells. 4-chloro-1-naphthol substrate solution was used to visualize the peroxidase label. The results of analysis of salivary and spermatic samples obtained from donors of various groups evidence that this EIA variant may be useful in forensic medicine.     

Cognitive limitations and affirmative action: The effects of aggregate versus sequential data in the perception of discrimination

The present experiment examined whether or not relatively simple cognitive and information-processing limitations may prevent us from recognizing instances of organizational discrimination. It was hypothesized that the perception of discrimination would be more difficult when the relevant information had been presented in a case-by-case basis rather than in aggregate format. The obtained results provided strong support for the original hypothesis. Subjects who had been presented with company data in aggregate format provided significantly higher ratings of discrimination than those subjects for whom the information had been presented in sequential form. The implications of these findings to the policy of affirmative action are also discussed.     

Occupational health ethics: OSHA and the courts

Recent court decisions have stressed the necessity for cost-benefit analysis in evaluating Occupational and Safety Health Administration (OSHA) standards, thus raising difficult ethical questions which this paper analyzes using classical approaches of deontology and teleology. Since both modes of analysis have deficiencies, the need for a synthesis using economic and noneconomic measures is suggested.