Evaluation of postmortem redistribution phenomena for commonly encountered drugs

We described the findings of a study into the post-mortem redistribution (PMR) of 76 drugs found in 129 drug-related cases between 2006 and 2009. Seventy six drugs (psychotropic drugs (n=14), antidepressants (n=9), sedatives (n=6) and so on) were simultaneously quantified in cardiac and peripheral blood by gas chromatography-mass spectrometry (GC/MS) or liquid chromatography-tandem mass spectrometry (LC/MS/MS). The absence, possibility or presence of PMR of drugs was determined according to the ratios of cardiac to femoral blood concentrations (C/P ratios). Proxyphylline (C/P ratio: 0.85) showed no PMR; carbamazepine was not subject to PMR; a potential for PMR of lorazepam and mirtrazapine cannot be excluded; chlordiazepoxide is subject to PMR; acetaminophen and alprazolam exhibit minimal PMR; amitriptyline and benztropine exhibit PMR. Codeine (C/P ratio: 4.9), zolpidem (C/P ratio: 3.74), chlorpromazine (C/P ratio: 2.97), fluoxetine (C/P ratio: 2.83) and propranolol (C/P ratio: 2.72) had the largest C/P ratios. Postmortem drug concentrations showed variations depending on sampling sites and characteristics of the drugs. It is continuously necessary to analyze commonly used or abused drugs in simultaneously collected cardiac and peripheral blood to establish significant reference values for PMR. These findings can be used to reach a conclusion about the cause and manner of death.     

Child Maltreatment Risk Inventory: Pilot Data for the Cleveland Child Abuse Potential Scale

This article presents data on the development of a child maltreatment actuarial risk inventory, The Cleveland Child Abuse Potential Scale (C-CAPS). The study consisted of three groups in a juvenile court setting: child custody cases without indication of maltreatment (N = 34), cases where maltreatment was indicated (N = 37), and a third middle ground group of cases referred to the court’s Diagnostic Clinic (N = 47). This third group of cases had not elevated to court involvement with a filing of child maltreatment. Study results provide compelling support for overall classification accuracy, with 100% specificity and 95% sensitivity and an overall hit rate of 98%, when only the maltreatment and non-maltreatment groups were compared. Adding the third group of possible maltreatment cases dropped the overall hit rate to 71%. The instrument was able to correctly classify 85% of Non-Maltreatment cases and 76% of Maltreatment cases. The overall factor structure of the instrument is also reviewed.     

A comparison of rape and molest offenders in prison psychiatric treatment

Differences in offense history, brain functioning, and psychological functioning of rape (n = 45) and molest offenders (n = 15) who were receiving psychiatric treatment while in prison were evaluated. Significant differences were found in each of these domains. Rape offenders were more likely to have histories of high violence offenses other than sexual offense, including murder, serious juvenile offenses, and both juvenile and adult sexual offenses. Rape offenders were more likely to show lower intellectual functioning and diffuse brain dysfunction associated predominantly with temporal and prefrontal brain cortices. Rape offenders were also more likely to display psychological functioning associated with illogical thinking and disordered attachment but less immature self-focus and fewer feelings of alienation than demonstrated by molest offenders. Implications for treatment and social policy for sexual offenders are suggested. Logistic regression demonstrated that these neuropsychological measures resulted in 71.7% accurate prediction and Rorschach measures resulted in 79.2% accurate prediction in differentiating rape from molest offenders. Implications for theoretical understanding of sexual offending are discussed.     

政府政务外包及其实现路径研究

随着政府自身提高管理和服务能力、降低行政成本需求的增强,经济全球化和信息化时代公民参与意识的提高以及层级政府间压力的加大,政府政务外包日渐成为一种新型政府治理工具,其领域和范围也不断拓展。据此,文章对当前我国政府政务外包的发展状况和动因进行了分析,进而探讨了政府政务外包的公共性、效率和合法性三个限度,并提出了明确政务外包中的政府职责、提高政府政务外包管理能力、坚持依法推行政务外包等三条外包实现路径。     

蒙古与日本的全面伙伴关系

本文回顾了蒙古与日本的历史关系,并概述了近年来蒙日关系各方面的发展.     

技术标准中的必要专利研究

介绍了主要国际标准化组织、我国国家标准化管理委员会在技术标准制定中与专利相关的规定.针对我国标准的制定/修订过程中采用国际标准,以及用户使用标准时可能涉及的专利问题,着重论述了如何判断标准中的必要专利,并提供了判断必要专利所需要的信息资源.     

对减刑案件检察监督权配置的思考

目前,由监狱行使提请减刑建议权,不符合刑法基本原则的要求,并且在实践中已经出现了监狱提请减刑与法院裁定减刑标准不一致,人民法院减刑裁判权呈虚设状态,减刑案件被监狱提请机关控制的不正常现象。解决问题的方法就是将提请减刑案件的启动权归由人民检察院行使。     

Implementation and Validation of the Teleshake Unit for DNA IQ™ Robotic Extraction and Development of a Large Volume DNA IQ™ Method

Abstract: Automated platforms used for forensic casework sample DNA extraction need to be versatile to accommodate a wide variety of sample types, thus protocols frequently need modification. In this study, DNA IQ? methods previously developed for the Biomek^® 2000 Automation Workstation were adapted for the Teleshake Unit using normal volumes and all deepwell extraction, and a large volume DNA IQ? method developed. DNA purification without detectable contamination of adjacent reagent blanks is reported in the extraction of tissue samples containing several micrograms of DNA. Sensitivity and contamination studies demonstrated similar performance with the manual organic extraction method for bloodstain dilution samples. Mock casework samples demonstrated the effectiveness of the Teleshake and Teleshake large volume methods. Because of the performance and increased versatility of the DNA IQ? extraction with these modifications, the Teleshake Unit has been implemented in both normal and large volume automated DNA extractions at the Virginia Department of Forensic Science.     

Listening to law enforcement officers: The promises and problems of police - adult probation partnerships

Police-probation partnerships have increased in recent years, but evaluations of such partnerships are rare. Particularly within probation agencies, such partnerships can be perceived as an abandonment of service responsibilities in favor of enforcing the law against probationers, but the views of police officers involved in these partnerships have not been examined in the past. The current study began this process by examining the perceptions of law enforcement officers in Texas. In particular, the following questions were addressed: (1) whether they experience role conflict or role ambiguity, (2) how they perceive the effectiveness of partnerships, and (3) how they evaluate the impact of partnerships on crime reduction. Three partnership patterns were identified using cluster analysis. The analysis revealed a significant relationship between the extent of partnerships and the perceptions of law enforcement officers on the partnerships. The policy implications of the findings are discussed.