Drug and chemical blood-level data 2001.

Current blood-level data are presented for drugs and chemicals of toxicologic interest. The data represent an update of previously published compilations of therapeutic, toxic and lethal blood-levels.     

Y-chromosomal STR haplotype in the Japanese population.

Allele and haplotype frequencies of seven Y-chromosome STR loci from samples of 108 unrelated Japanese males living in Aichi Prefecture.     

Barriers Inhibiting Industry from Partnering with Universities: Evidence from the Advanced Technology Program

This paper describes a small, unique set of project data that was assembled as part of a larger study on universities as research partners. Herein, we summarize, to the extent possible, our interpretation of what the project data reveal about barriers, intellectual property (IP) concerns in particular, inhibiting industry from partnering with universities.     

Firearm examination: Examiner judgments and computer‐based comparisons

Forensic firearm examination provides the court of law with information about the source of fired cartridge cases. We assessed the validity of source decisions of a computer‐based method and of 73 firearm examiners who compared breechface and firing pin impressions of 48 comparison sets. We also compared the computer‐based method's comparison scores with the examiners' degree‐of‐support judgments and assessed the validity of the latter. The true‐positive rate (sensitivity) and true‐negative rate (specificity) of the computer‐based method (for the comparison of both the breechface and firing pin impressions) were 94.4% and at least 91.7%, respectively. For the examiners, the true‐positive rate was at least 95.3% and the true‐negative rate was at least 86.2%. The validity of the source decisions improved when the evaluations of breechface and firing pin impressions were combined and for the examiners also when the perceived difficulty of the comparison decreased. The examiners were reluctant to provide source decisions for "difficult" comparisons even though their source decisions were mostly correct. The correlation between the computer‐based method's comparison scores and the examiners' degree‐of‐support judgments was low for the same‐source comparisons to negligible for the different‐source comparisons. Combining the outcomes of computer‐based methods with the judgments of examiners could increase the validity of firearm examinations. The examiners' numerical degree‐of‐support judgments for their source decisions were not well‐calibrated and showed clear signs of overconfidence. We suggest studying the merits of performance feedback to calibrate these judgments.     

Clustering of multiple sclerosis in Galion, Ohio, 1982-1985

Epidemiologic evidence indicates that the outbreak of 30-40 cases of multiple sclerosis and other demyelinating syndromes in Galion, Ohio, USA, during 1982-1985 was related to an excess concentration of heavy-metal wastes, especially of cadmium and chromium in sewage and river water. Both multiple sclerosis and myasthenia gravis were diagnosed by board-certified neurologists.