Quantitative analysis of chlorpromazine by electron spin resonance (ESR) spectroscopy

A simple and sensitive method is described for quantitative analysis of chlorpromazine in blood, serum, urine and tissue homogenate. The chlorpromazine cation radical produced by adding perchloric acid and 2,3-dichloro-5,6-dicyano-p-benzoquinone to the sample can be detected by the ESR method at room temperature. The sensitivity limit is 10 ng, that is, 20 μl of the solution containing 0.5 μg chlorpromazine/ml. The time needed for the measurement is within 10 min. The chlorpromazine radical thus produced is very stable; for example, 95% of the radical was observed after 24 h. The advantage of this method is discussed by comparing with the ordinary spectrophotometry which requires the purification of the sample.     

A Working Class Critique of Criminological Theory

The absence of a thoroughly developed, working class critique of criminological theory has resulted in bias in the creation of knowledge regarding crime and deviance. Much as feminist writings illuminated the unique problems related to gender, and works by those discussing racial and ethnic minorities highlighted the special concerns related to race and ethnicity, a working class perspective can expose the particular issues having to do with class. A brief discussion will be presented dealing with the portrayal of working class people in the media, and the complicity of academia in allowing working class stereotypes to persist. A sketch of a working class perspective will then be developed, and it will be used to critique fourteen of the major criminological theories today in terms of their relative sensitivities and considerations of the class factor in crime and justice issues. The final section places each of the fourteen theories on a continuum from those that do not consider the working class experience at all to those that give the working class experience full consideration. This revised version was published online in July 2006 with corrections to the Cover Date.     

Observations of high velocity bloodspatter on adjacent objects

In a recent homicide investigation, high velocity backspatter was observed on the sleeve cuff of the accused. These minute droplets were discovered only after microscopic examination and were limited in number. A study was initiated to determine if these were truly backspatter droplets or transferred blood produced from light contact with a bloody item. It was observed that the backspattered blood was primarily limited to contact or near contact shots. An exception was a shot into an already bloody surface. It was found that backspattered blood would deposit on the shooter's shirt sleeve irrespective of the weave pattern. Transferred blood was observed only on the fiber tops. This information was found to be useful in reconstruction of events in suicides as well as possible homicides.     

Sexuality and Law in the New Europe

Kees Waaldijk and Andrew Clapham (eds), Homosexuality: A European Community Issue—Essays on Lesbian and Gay Rights in European Law and Policy