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111.
Huberfeld N 《Journal of health law》2007,40(2):241-265
The pharmaceutical industry has been receiving greater scrutiny lately due in large part to the many public and private legal enforcement actions taken against pharmaceutical manufacturers. These enforcement actions, along with legal developments such as the OIG Compliance Guidance for Pharmaceutical Manufacturers, the Sarbanes-Oxley Act's statutory guidelines for public corporations, the HIPAA privacy regulations, and the Medicare Modernization Act, have the potential to encourage the pharmaceutical industry to self-regulate beyond the bounds currently required by the law. After a brief overview of enforcement actions and compliance programs directed toward the pharmaceutical industry, this Article reviews a similar situation the hospital industry faced when Medicare promulgated major reimbursement modifications. The Article proposes that the pharmaceutical industry, in the face of such intense scrutiny and uncertainty, should implement more rigorous self-regulation. Without more stringent self-regulation, this intense interest in the pharmaceutical industry may result in a regulatory push that establishes unanticipated and cumbersome measures for the industry. 相似文献
112.
Nicole L. Ledbetter M.S. Barbara L. Walton B.S. Pedro Davila B.S. William D. Hoffmann B.S. Richard N. Ernest B.S. Guido F. Verbeck IV Ph.D. 《Journal of forensic sciences》2010,55(5):1218-1221
Abstract: This article presents the novel instrumentation of nanomanipulation coupled to nanospray ionization‐mass spectrometry, which is used to directly probe trace analytes found on individual fibers. The low detection limits and sample volumes associated with nanospray ionization‐mass spectrometry make it the ideal instrument to implement for trace analysis. Nanospray ionization‐mass spectrometry, coupled with the nanomanipulator, allows for the direct probing of trace particulates on fibers. The technique is demonstrated by dissolving an electrostatic particle of cocaine from a fiber, collecting the analyte solution in a nanospray tip, and transferring the tip directly to the mass spectrometer to complete analysis. The utility of this technique is evident through the minimal sample preparation and short analysis time. The use of nanomanipulation coupled to nanospray ionization‐mass spectrometry could improve on current trace particulate analysis by reducing both detection limits and sample size required to complete analysis. 相似文献
113.
114.
Isabelle Montani Raymond Marquis Nicole Egli Anthonioz Christophe Champod 《Science & justice》2019,59(1):1-8
This paper explores procedural mechanisms to resolve differing conclusions when two experts have initially worked independently. These experts can be two human examiners or one of them may be a computer-based model. The resolving process is presented as part of the ACE-V protocol adopted widely in pattern recognition areas (e.g. fingerprints, footwear marks, toolmarks or handwritings/signatures comparisons). It set the conditions of operations and delineates a resolving process that is based on the principles of transparency and detailed argumentations. We predict a gradual but steady introduction of computer-based models in the forensic pattern recognition areas. In our opinion, the rules to resolve differing opinions ought to be articulated and documented in the form of standard operating procedures, before any deployment in casework practice. 相似文献
115.
H. Theodore Harcke M.D. Timothy Monaghan M.D. Nicole Yee B.S. Louis Finelli M.D. 《Journal of forensic sciences》2009,54(5):1123-1126
Abstract: Our objective is to document the recovery of DNA from the spinal cord or surrounding dura mater in 11 cases of severely burned human remains. Radiographs established that portions of charred tissue contained spine segments. Multidetector computed tomography (MDCT) revealed that each spine specimen contained an intact spinal cord remnant. A full DNA profile was obtained from seven specimens using spinal cord dura mater in six specimens and spinal cord medulla in one specimen. A partial profile was obtained from four specimens (spinal cord dura mater, 2; spinal cord medulla, 2). Bone and muscle surrounding the spinal cord appear to insulate nucleic acid containing tissue from critical thermal degradation. The spinal cord, which is easily identified by MDCT examination of remains and easily recovered at the postmortem examination, can be a source of DNA with extraction yields comparable with other tissue sources. Specimens of dura mater are preferable as processing time is faster than bone. 相似文献
116.
Little is known about the correlates of white-collar victimization, and even less is known about white-collar crime reporting. In this article, the extent to which predictors of fraud victimization are the same as the predictors of fraud reporting is examined. Using a national sample of fraud victims, these findings were consistent with prior research in that involvement in risky behaviors and age were found to be important predictors of fraud victimization. Additionally, the specific factors that are influential in predicting fraud victimization appear to vary across offense type. Unfortunately, little was revealed regarding the predictors of the official reporting of fraud victimizations. Future research needs to further unravel the importance of risky behavior in both victimization and reporting, as well as to focus on a broader array of white-collar crimes. 相似文献
117.
Nicole George 《Development in Practice》2009,19(8):981-996
This article examines a 40-year history of women's organising in Fiji, in order to show how the political goals pursued by active citizens can be shaped by an interplay of domestic and international political contingencies. This approach challenges the common and somewhat idealised definitions of active citizenship that focus upon actors' capacity to mobilise collectively behind political goals independent of those that motivate the state or the market. Rather, active citizenship is viewed as a realm of political activity constituted in ways that both reflect and contest contingent factors prevailing globally and locally. 相似文献
118.
Nicole Wichmann 《Swiss Political Science Review》2009,15(4):653-682
From the point of view of modes of governance and constellations of interdependence, EU research policy offers ideal conditions for the flexible inclusion of non‐member states: it is based on transgovernmental coordination through policy networks rather than supranational legislation, it follows scientific rather than political imperatives, and cooperation is in the interest of both the EU and of Switzerland. This article analyses the degree to which these factors have allowed for Switzerland's inclusion into the regulatory and organisational aspects of EU research policy, and highlights the limits of such flexible sectoral integration. 相似文献
119.
The role of media in promoting political accountability and citizen participation is a central issue in governance debates. Drawing on research into the interactions between radio station owners, journalists, audiences and public authorities during Somali radio call-in programmes we argue that these programmes do not simply offer a new platform for citizens to challenge those who are governing but that they are also spaces where existing power structures reproduce themselves in new forms. We identify the ways the programmes are structured and the different motivations the audience has for participation. Three types of programmes are identified and their relationships with patronage, politics, and performance are examined. Rather than focusing on normative assumptions about the media as a tool of accountability, the article emphasises the importance of understanding radio programmes in their social and political environment, including the overlapping relationships between on-air and off-air networks. 相似文献
120.
Kaylin M. Greene Bora Lee Nicole Constance Kathryn Hynes 《Journal of youth and adolescence》2013,42(10):1557-1572
Prior research suggests that youths’ engagement in out-of-school time programs may be a crucial factor linking program participation to positive outcomes during adolescence. Guided by the theoretical concept of flow and by stage-environment fit theory, the present study explored correlates of engagement in youth programs. Engagement was conceptualized as the extent to which youth found the program activities enjoyable, interesting, and challenging. The current study examined how program content, monetary incentives, and youth demographic characteristics were linked to youth engagement among a sample of primarily low-income middle and high school youth attending 30 out-of-school programs (n = 435, 51 % female). Results from multilevel models suggested that program content and staff quality were strongly associated with youth engagement. Youth who reported learning new skills, learning about college, and learning about jobs through activities in the program were more engaged, as were youth who found the staff caring and competent. Results demonstrated that the link between learning content for the future and engagement was stronger for older youth than younger youth. In addition, there was a trend suggesting that providing a monetary incentive was associated negatively with youth engagement. Taken as a whole, these findings have important implications for researchers, practitioners, and policymakers interested in understanding the characteristics of out-of-school time programs that engage older youth. 相似文献