对法医临床鉴定若干问题的思考

本文针对法医临床鉴定工作中存在的对鉴定时限、鉴定机构权限、鉴定人资格、法医鉴定、医学鉴定等概念的认识误区进行了分析,并就解决这些问题、进一步提高法医临床鉴定水平的途径作了有益的探讨。     

Polymorphisms of eight STR loci in Chinese and African (Xhosa)populations

Allele frequencies for eight short tandem repeal loci (D16S539, D7S820, D13S317, D5S818, CSF1PO, TPOX, TH01 and vWA) were obtained from samples of 100 Chinese and 96 African (Xhosa) unrelated individuals.     

谈公安机关人力资源的开发与管理

公安机关人力资源的开发和管理是一项重要的社会管理活动.但从人力资源环境、人力资源的获取、人力资源的开发与管理三方面看,公安机关的人力资源的开发和管理还存在一些问题.公安机关在积极推行行政体制改革的同时,还要从内部的人事着手,变传统的人事管理为人力资源管理,通过引进现代人力资源管理的理念和技术,改善并提高管理的效率与服务的质量,以更好地履行服务公众的职责.     

人类酪氨酸羟化酶基因SNP多态性与精神疾病的相关性

目的通过调查人类酪氨酸羟化酶（tyrosine hydroxylase,TH）基因的部分SNP在正常及疾病群体中的分布,探讨TH基因与精神疾病的相关性。方法采用DNA测序和实时荧光定量PCR技术,选择正常人、精神分裂症患者、抑郁症患者群体及部分精神分裂症患者家系的DNA为样本,对TH基因外显子3中的G334A和内含子9中的C5162G两个SNP位点进行分析。结果（1）G334A位点G和A的等位基因频率分布分别为：正常人群0.214和0.786;精神分裂症群体0.133和0.867;抑郁症群体0.116和0.884。（2）C5162G位点C和G的等位基因频率分布分别为：正常人群0.961和0.039;精神分裂症群体0.962和0.038;抑郁症群体0.959和0.041。结论G334A基因频率的分布在正常人群与精神分裂症和忧郁症群体之间的差别均有统计学意义,而C5162G基因频率的分布无统计学意义。     

A LDR‐PCR Approach for Multiplex Polymorphisms Genotyping of Severely Degraded DNA with Fragment Sizes <100 bp*

Abstract: Reducing amplicon sizes has become a major strategy for analyzing degraded DNA typical of forensic samples. However, amplicon sizes in current mini‐short tandem repeat‐polymerase chain reaction (PCR) and mini‐sequencing assays are still not suitable for analysis of severely degraded DNA. In this study, we present a multiplex typing method that couples ligase detection reaction with PCR that can be used to identify single nucleotide polymorphisms and small‐scale insertion/deletions in a sample of severely fragmented DNA. This method adopts thermostable ligation for allele discrimination and subsequent PCR for signal enhancement. In this study, four polymorphic loci were used to assess the ability of this technique to discriminate alleles in an artificially degraded sample of DNA with fragment sizes <100 bp. Our results showed clear allelic discrimination of single or multiple loci, suggesting that this method might aid in the analysis of extremely degraded samples in which allelic drop out of larger fragments is observed.     

Adverse Childhood Experiences Affect Health Risk Behaviors and Chronic Health of Iowans

Adverse childhood experiences (ACEs), include childhood abuse and household dysfunction, and are associated with a variety of behavioral risk factors and chronic illnesses in adulthood. This study replicates the original ACEs study (Felitti et al. American Journal of Preventive Medicine, 14(4), 245–258. doi: 10.1016/s0749-3797(98)00017-8, 1998) with a representative sample of adults in Iowa. Data come from the Behavioral Risk Factor Surveillance System (BRFSS) survey of 2012 when ACE assessments were first introduced in Iowa by the Centers for Disease Control and Prevention (2012). The majority of adults in Iowa (58%) have experienced at least one ACE, and depending on the type of ACE, co-occurrence of ACEs ranged from 76% to 97%. Health risk behaviors in adulthood, such as drinking, smoking, and obesity were significantly related to the number of ACEs experienced. ACEs were also associated with depression. Chronic health outcomes including heart disease, stroke, and COPD were also significantly predicted by the number of ACEs. This replication study demonstrates that the need for intervention and prevention programs in Iowa are similar to the needs found in other states in the U.S. for addressing the consequences of ACEs.     

金融危机对俄罗斯发展战略的影响

金融危机使俄罗斯经济遭重创,2009年俄GDP增长率在全球前十大经济体中排名最后。其原因主要是经济结构畸形、金融系统脆弱、企业外债规模过大等。总结金融危机爆发后的经验教训,俄提出了振兴俄罗斯的“现代化战略”,并已开始显现影响力。由于受国内经济结构以及与西方国家关系的影响,俄“现代化战略”的全面实现尚会面临诸多困难,但俄未来的发展机遇仍会大于挑战。     

浅探非智力因素在教学中的作用

所谓非智力因素,指的是一个人智力因素以外的诸多因素,包括他的一切心理活动,如动机、兴趣、情感、意志和性格等。智力因素和非智力因素的对立统一决定着一个人的质量。一般来说,智力因素和非智力因素好的学生,都表现为思想上进学习好,容易成为好学生,而两种因素的某些方面有欠     

生命叙事在道德教育中的应用

生命叙事是一种古老而又充满活力的道德教育方式,它具有自我性、日常生活性和生成性的特点。它产生教育作用的内在机制在于:叙事过程中故事本身内在的教育价值,道德学习的特点。教师在道德教育中采用生命叙事应注意如何选择故事及叙事“视点”和方式。     

精神障碍者民事行为能力评定量表研制

目的制定精神障碍者民事行为能力评定量表,并探讨其在司法精神病鉴定中的适用性。方法将民事行为能力的考量指标进行细化,经讨论、咨询专家后确定量表条目,按照评定逻辑顺序排列并完成操作手册,形成评定量表。在四家司法鉴定机构试用量表。结果精神障碍者民事行为能力评定量表共有14个条目。共纳入202例样本,根据专家意见划分为完全、限制和无民事行为能力3组。3组量表总分分别为2.32±2.45、11.62±4.01、25.02±3.90,两两得分差异均具有统计学意义。全量表Cronbachα为0.9724,分半信度检验中两分半量表间具有较高的相关系数(r=0.9729,P=0.000);各条目与总分的Spearman相关系数在0.643～0.882(P=0.000)。量表得分结论与专家意见的分组结论一致性较高(κ=0.841,P=0.000)。7个因子被有效纳入判别方程,92.6%的样本回代划分正确。结论精神障碍者民事行为能力评定量表具有良好的信度和效度,能对精神障碍者的民事行为能力进行有效分类。