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871.
872.
Vacuum metal deposition (VMD) is a highly sensitive technique originally introduced for detecting latent fingermarks on smooth non-porous surfaces such as carrier bags, plastics and glass. The current study explores whether VMD can be used in the examination of clothing from physical and sexual assault cases in order to visualise identifiable fingermark ridge detail and/or palmar flexion crease detail, thus allowing potential areas to be indicated for DNA swabbing and/or to determine the sequence of events. Four different fabrics were utilised during this study - nylon, polyester, polycotton and cotton, along with 15 donors who ranged in their age and propensity to leave fingermarks, from good to medium to poor as determined by results obtained from test runs using paper and plastic carrier bags processed with VMD. Once samples were collected they were kept for a determined time (1, 2, 3, 4, 5, 6, 7, 14, 21 or 28 days) and then treated using the gold/zinc metal VMD process. From the results, it appears that greater ridge detail is visible on the smoother non-porous fabrics, such as nylon whereas on rougher porous fabrics, such as cotton, only empty prints and impressions, rather than any ridge details, were visible. All fabrics did however allow the development of touch marks that could be targeted for DNA taping thus potentially leading to a DNA profile and possible identification of a suspect.  相似文献   
873.
Stress-induced cardiomyopathy (SICM) is characterized by transient systolic dysfunction of the apical and/or midventricular myocardial segments in the absence of obstructive coronary artery disease and is unique in that it can manifest itself after acute emotional stress. Excessive amounts of catecholamines released from sympathetic nerve endings as well as from the adrenal medulla under stressful conditions are considered to produce intracellular Ca(2+) overload and cardiac dysfunction through the β(1)-adrenoceptor signal transduction pathway. We describe the clinical and pathomorphological findings in two stress-induced cardiomyopathy fatal cases. Levels of catecholamines and their metabolites in urine samples were assessed too. Morphological patterns seen in SICM result from the complex interplay between sympathetic innervations, β-receptor density and function and catecholamine sensitivity.  相似文献   
874.
Forensic entomotoxicology studies the usefulness of insects as alternative toxicological samples. Use of insects as alternative matrix for drug detection is well documented and recommended when conventional matrices such as blood, urine or internal organs are no longer available. However, several limitations of entomotoxicology have been highlighted, especially concerning interpretation of the drug concentrations in insects on human forensic cases. In addition, the lack of knowledge in pharmacokinetic of drugs in insects, large variability of experimental set-up and toxicological analysis compromise the utility of this science. This review focuses on the current knowledge of factors influencing drug detection in insects. Reasons for the current limitations, but also recommendations for future research are discussed and proposed in this paper.  相似文献   
875.
This study concerns the market for research collaboration between industry and universities. It presents an analysis of the population of all Italian university–industry collaborations that resulted in at least one international scientific publication between 2001 and 2003. Using spatial and bibliometric analysis relating to scientific output of university researchers, the study shows the importance of geographic proximity in companies’ choices of university partner. The analysis also reveals inefficiency in the market: in a large proportion of cases private companies could have chosen more qualified research partners in universities located closer to the place of business.  相似文献   
876.
This paper describes the latest stage of an ongoing attempt to update and upgrade CPTED’s concepts and actions and link them more closely to developments in architecture, design and crime science. The concept of territoriality, for example, is central to the practice domain of CPTED. Yet territoriality is only vaguely defined within that domain, as are the other core concepts such as activity support and target hardening; and all of them confusingly intersect and overlap. The paper attempts a remedy by developing a suite of definitions in depth, relating the core concepts to various frameworks and discourses developed for crime prevention and design against crime, and more generally exploring ways in which CPTED could become richer and more subtle. It will also consider the ‘dark side’ of the environment, covering offenders’ countermoves to prevention and their own counter-exploitation of space, buildings and what they contain. The ultimate intention is to produce a more rigorous, yet deeper and better-integrated conception of CPTED useful for practice, research and theory alike. The paper should be considered as work in progress, indicating what might be possible and stimulating debate rather than offering a definitive resolution of the issue. Further steps are suggested and constructive contributions from readers are invited.  相似文献   
877.
目的用复合荧光扩增体系调查辽宁鞍山岫岩满族无关个体D6S1043、D7S3048、D9S925、D11S2368、D14S608、D15S659、D17S1290、D20S470和GATA198B05等9个STR基因座的遗传多态性。方法用本实验室构建的9个常染色体STR基因座荧光复合扩增体系,对辽宁鞍山岫岩满族252个无关个体的DNA进行PCR扩增,3130型基因分析仪电泳检测扩增产物及等位基因分型标准物,GeneMapper誖3.2分析软件中导入本体系Panel和Bin,对电泳结果进行分析,按照重复序列重复次数命名等位基因,使用Power-StatsV12和GENEPOP软件进行统计学分析。结果 9个STR基因座在辽宁鞍山岫岩满族基因型频率分布均符合Hardy-Weinberg平衡(P﹥0.05),多态性信息含量在0.750~0.860之间,杂合度在0.794~0.881之间,个体识别力在0.918~0.968之间,非父排除概率在0.587~0.757之间,累积非父排除率为0.999 96,累积个体识别能力为0.999 999 999 999 1。结论这9个非CODIS系统STR基因座在鞍山岫岩满族群体中等...  相似文献   
878.
Admiral Harold R. Stark (1880–1972) was appointed Chief of Naval Operations in August 1939 and served in that role until removed in March 1942. It was on his watch that the Japanese raided Pearl Harbor on 7 December 1941. Nowadays the prevailing view of Stark seems to be largely shaped by the official verdict of the Secretary of the Navy, James V. Forrestal, namely that “Admiral Harold R. Stark, USN (Retired), shall not hold any position in the United States Navy which requires the exercise of superior judgment”. Our very different view is that Stark was a patriot who willingly sacrificed his reputation to preserve that of President Franklin D. Roosevelt and to enable him, as the one person capable of leading the Allies to victory in war against Nazi Germany, to assume his proper mantle.  相似文献   
879.
The ability to predict the timing and magnitude of future climate and temperature changes at a regional level has become increasingly important for corporate decision making and enterprise risk management. In the short term, companies could face decisions about acquisitions of water-dependent companies and natural resources or might be planning facilities or operations in communities vulnerable to erosion and flooding, changes in water supplies, and increasing health-care costs. In the intermediate term, companies need to assess these vulnerabilities to determine appropriate insurance coverage, plan for new infrastructure, implement preventative health-care programs, or protect natural resources. A technical approach needs to involve predictive tools that can provide bounding estimates at regional scales. The implications of those changes need to be translated to consequences that can affect specific businesses. Corporations must be cognizant of the uncertainties in this forecasting process and for that reason it is essential to link the likelihood of outcomes with the magnitudes of consequences. This article outlines an approach that is gaining traction as a way to address this complex matter.  相似文献   
880.
A statistical methodology for the objective comparison of LDI-MS mass spectra of blue gel pen inks was evaluated. Thirty-three blue gel pen inks previously studied by RAMAN were analyzed directly on the paper using both positive and negative mode. The obtained mass spectra were first compared using relative areas of selected peaks using the Pearson correlation coefficient and the Euclidean distance. Intra-variability among results from one ink and inter-variability between results from different inks were compared in order to choose a differentiation threshold minimizing the rate of false negative (i.e. avoiding false differentiation of the inks). This yielded a discriminating power of up to 77% for analysis made in the negative mode. The whole mass spectra were then compared using the same methodology, allowing for a better DP in the negative mode of 92% using the Pearson correlation on standardized data. The positive mode results generally yielded a lower differential power (DP) than the negative mode due to a higher intra-variability compared to the inter-variability in the mass spectra of the ink samples.  相似文献   
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