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排序方式: 共有1327条查询结果,搜索用时 109 毫秒
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C. Phillips A. Salas J.J. Snchez M. Fondevila A. Gmez-Tato J. lvarez-Dios M. Calaza M. Casares de Cal D. Ballard M.V. Lareu . Carracedo The SNPforID Consortium 《Forensic Science International: Genetics Supplement Series》2007,1(3-4):273-280
Tests that infer the ancestral origin of a DNA sample have considerable potential in the development of forensic tools that can help to guide crime investigation. We have developed a single-tube 34-plex SNP assay for the assignment of ancestral origin by choosing ancestry-informative markers (AIMs) exhibiting highly contrasting allele frequency distributions between the three major population-groups. To predict ancestral origin from the profiles obtained, a classification algorithm was developed based on maximum likelihood. Sampling of two populations each from African, European and East Asian groups provided training sets for the algorithm and this was tested using the CEPH Human Genome Diversity Panel. We detected negligible theoretical and practical error for assignments to one of the three groups analyzed with consistently high classification probabilities, even when using reduced subsets of SNPs. This study shows that by choosing SNPs exhibiting marked allele frequency differences between population-groups a practical forensic test for assigning the most likely ancestry can be achieved from a single multiplexed assay. 相似文献
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Fiona de Londras 《The Modern law review》2008,71(1):36-58
This article outlines the US Supreme Court's approach to the habeas corpus entitlements of suspected terrorists detained in Guantánamo Bay and argues for the extension of constitutional habeas corpus rights to them. The article considers two ways in which the Supreme Court might carry out this task: first, 'the territorial approach' (based on domestic legal principles of 'unincorporated territories' and principles of leasehold), and secondly, 'the extraterritorial approach' (based on international purposive approaches to the reach of human rights treaties exemplified by the European Court of Human Rights' Article 1 jurisprudence). For reasons of effectiveness of protection, the Article expresses a clear preference for the latter. The House of Lords decision in R (Al-Skeini) v Secretary of State for Defence (2007) is proposed as a template for such a development. Finally the article refutes arguments rejecting such a development based on the 'trade-off thesis' and perceptions of judicial competence. 相似文献
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Thirsa Kraaijenbrink George L. van Driem Karma Tshering of Gaselô Peter de Knijff 《Forensic science international》2007
We studied the allele frequency distribution of 21 autosomal STR loci contained in the AmpFlSTR® Identifiler™ (Applied Biosystems), the Powerplex®16 (Promega) and the FFFL (Promega) multiplex PCR kits among 936 individuals from the Royal Kingdom of Bhutan. As such these are the first published autosomal DNA results from this country. 相似文献
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