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Regions can be considered as “regional innovation systems,” but the question of whether and to what extent technology transfer is taking place at this or other (e.g., national and global) levels remains empirical. The theme issue contains a number of case studies of “regional innovation systems” within the European Union. Other papers elaborate on the pros and cons of the systemic approach to the technology transfer processes involved, or make comparisons across regions. In this introduction, the editors discuss the relations between regional policies, technology and innovation policies, and the integration of these different aspects into (potentially regional) systems of innovation. Under what conditions can “technology transfer” be considered as a mechanism of integration at the regional level?  相似文献   
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Although much criticized, the “Cosa Nostra” theory of organized crime continues to exert considerable influence over lawmakers and law enforcement officials. This theory has been extensively studied on a national level, but few local case studies trace the transition from the multiethnic organized crime of the 1930s and 1940s to the (supposed) Italian hegemony of the years since 1960. Philadelphia provides an excellent opportunity for such a study, as the base of a strong Jewish-dominated structure before 1960 and a “Mafia town” thereafter.A major concern of this article is the manner in which the history of crime in the city was retroactively rewritten during the 1970s, in order to provide a basis for contemporary theories and bureaucratic needs.  相似文献   
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This study examines how programs sponsored through the National Institute of Standards and Technology's Manufacturing Extension Partnership (MEP) have influenced the organization and delivery of industrial modernization services to small and medium-sized manufacturers in regions in the United States. The study found that increased service coordination has occurred and that this, in turn, has mostly improved the quality and comprehensiveness of assistance delivered to firms. But there are also some costs and drawbacks associated with multi-partner service delivery approaches. The study identifies and examines best practices that can help MEP centers increase the effectiveness of service coordination. This paper draws upon research supported by the U.S. Department of Commerce, National Institute of Standards and Technology under award 50SBNBC8305. The views expressed are the authors' and do not necessarily reflect those of the research sponsor.  相似文献   
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Opioid‐related mortality happens, even in healthcare settings. We describe serial postmortem fentanyl blood concentrations in a hospital inpatient who fatally abused transdermal fentanyl. This is a single‐patient case report. A 42‐year‐old man with lymphoma was started on transdermal fentanyl therapy while hospitalized for chronic abdominal pain. The patient was last seen awake 1.3 h prior to being found apneic and cyanotic. During the resuscitation attempt, a small square‐shaped film was removed from the patient's oropharynx. Femoral blood was collected 0.5 and 2 h postmortem, and the measured fentanyl concentration increased from 1.6 to 14 ng/mL. Study limitations include potential laboratory or collection errors and missing data. (i) Providers must be vigilant for signs of fentanyl patch abuse. (ii) Postmortem blood concentrations are not static postmortem, likely secondary to decreasing pH, increased aqueous solubility, and tissue redistribution, and are therefore unlikely to accurately represent antemortem blood concentrations.  相似文献   
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The United Kingdom continues to undergo a rapid process of constitutional change, with an ongoing redistribution of law‐making and governmental powers to different parts of the Union under an expanded rubric of ‘devolution'. This article illuminates a pervasive sense of territorial constitutional crisis and opportunity in the most recent period, familiarly associated with, but not confined to, Scotland. Constructive and flexible federal‐type responses inside a famously uncodified constitution are championed. Wales, commonly treated as a junior partner in the United Kingdom, presents special challenges for constitutional and legal analysis and distinctive perspectives on the Union which have not received the attention they deserve. In tackling this deficiency, the article elaborates a ‘new Union’ concept of a looser and less hierarchical set of constitutional arrangements in which several systems of parliamentary government are grounded in popular sovereignty and cooperate for mutual benefit.  相似文献   
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