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261.
Marianna Shvartsbeyn M.D. Daniel G. K. Phillips M.D. Michael A. Markey M.D. Alan Morrison M.D. Joyce L. DeJong M.D. Rudy J. Castellani M.D. 《Journal of forensic sciences》2010,55(5):1389-1392
Abstract: Intracerebral hemorrhage (ICH) is a well‐recognized complication of recreational cocaine use. The precise mechanism of the cocaine‐induced hemorrhagic event is unclear, although multiple factors have been implicated. We report a case of a 62‐year‐old woman who suffered left parieto‐occipital ICH with herniation and death, following a cocaine binge. Microscopic examination also revealed extensive cerebral amyloid angiopathy (CAA) in the vicinity of the hemorrhage. We additionally studied brain tissue in eight subjects between ages of 60 and 80 who were positive for cocaine metabolites at autopsy; of these, none had vascular amyloid‐β deposits by immunohistochemistry. Whereas we found no evidence that chronic cocaine use is a risk factor for CAA, given the age‐associated nature of CAA and the aging population using cocaine, CAA‐induced hemorrhage in the setting of cocaine use may be more common than recognized. This is the first reported case of CAA‐associated ICH precipitated by cocaine. 相似文献
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Nicola Phillips Leonardo Sakamoto 《Studies in Comparative International Development (SCID)》2012,47(3):287-315
For large parts of the world's poor labour force, participation in global production networks (GPNs) is associated not with poverty reduction and ??social upgrading??, but with highly precarious, unprotected and exploitative forms of work and employment, resulting in a perpetuation, rather than alleviation, of chronic poverty. In this article, we seek to understand these dynamics of ??adverse incorporation?? in the context of Brazilian agriculture, focusing on the extreme ends of the spectrum of exploitation associated with what, in Brazil, is usually termed ??slave labour??. We explore two questions which reveal the circular character of adverse incorporation. First, to what extent, in what ways and under what circumstances does chronic poverty foster patterns of precarious and exploitative employment within GPNs for poor workers? Second, to what extent, in what ways and under what circumstances can the workings of GPNs, and the terms on which poorer workers are incorporated into them, be said to produce and reproduce chronic poverty? 相似文献
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Y chromosome haplotype data was collected for 155 Irish males residing in the Republic of Ireland. Eleven short tandem repeat (STR) markers: DYS19, DYS385, DYS389I, DYS389II, DYS390, DYS391, DYS392, DYS393, DYS437, DYS438 and DYS439 were analysed and the allele and haplotype frequencies calculated. This Irish data is presented here and was found to be less diverse when compared with the neighbouring UK population. 相似文献
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Mary Kathleen Deutscher Keith D. Walker Peter W.B. Phillips 《Canadian public administration. Administration publique du Canada》2019,62(2):181-201
The policy and practice of public administration are caught between two seemingly incommensurate goals. Public servants are expected to be responsible to the oversight and control of democratically elected governments, yet, as the policy space becomes more complex, are forced to exercise more judgment and discretion in their responsibilities. Individual, collective, and professional conscience is motivated across this spectrum of challenges. This article explores the concepts of discretion and conscience in theory and practice in the Canadian context. It offers insights into how conscience can, and perhaps must, be both accommodated and supported more appropriately in the practice of 21st‐century public administration and service. At root, we argue that an array of strategies and approaches may help to build relational reciprocity to a broader set of norms that are necessary for efficient and effective governance. 相似文献
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The impact of fiscal decentralisation on LDC economic growth and development is widely debated in the development literature. Notwithstanding this, there has been little attempt to test systematically this relationship. Accordingly, in this note we present an empirical examination of the relationship between the level of fiscal decentralisation and economic growth rates across a sample of twenty‐three LDCsfrom 1974 to 1991. We fail to find, however, any strong, systematic relationship between the two among our sample of LDCs. 相似文献