Acute Benztropine Intoxication and Fatality

A woman was found unresponsive with an empty bottle of Cogentin^® prescribed to another. Admitted to an area hospital, her condition steadily declined until death 29 h after admission. Following toxicological screening on hospital (admission) whole blood, the only significant compound detected was benztropine. Benztropine was confirmed at 0.28 mg/L – the highest antemortem blood concentration recorded in a case of toxicity or fatality uniquely associated with benztropine. A second serum antemortem specimen showed a benztropine concentration of 0.19 mg/L. Despite over 24 h in the hospital, benztropine was also found in the postmortem specimens collected at autopsy. Peripheral blood, central blood, liver, and gastric concentrations were 0.47 mg/L, 0.36 mg/L, 9.6 mg/kg, and 44 mg, respectively. These results indicate that benztropine exhibited a potential difference between whole‐blood and serum (plasma) concentrations. Additionally, in consideration of literature data, benztropine was found indicative of a compound prone to at least some postmortem redistribution.     

Fatal Oral Methylphenidate Intoxication with Postmortem Concentrations

Methylphenidate (MPD) is a widely prescribed stimulant used primarily for the treatment for attention‐deficit/hyperactivity disorder (ADHD). Suicide attempts involving MPD ingestion have been well described; however, deaths attributed solely to MPD ingestion have not been reported. A 62‐year‐old woman was found dead on her floor. The only discrepancy in among her medication quantities was that >three hundred 10 mg MPD tablets were missing. Analysis utilizing gas chromatography–mass spectrometry revealed elevated postmortem MPD peripheral and central blood, liver and vitreous humor concentrations. Considering both the central blood to peripheral blood ratio (0.89) and the liver to peripheral blood ratio (3.3), MPD does not appear subject to significant postmortem redistribution. With no other identifiable cause of death, we report what appears to be the first isolated MPD ingestion associated with a fatality.     

Social perception of rape victims

Since 1975, 40 states have enacted “rape shield” statustes which limit the admissibility of a rape victim's prior sexual history in court. These reforms have assumed that jurors regard prior sexual history evidence as much too probative of a victim's credibility and moral character, and that such perceptions have a prejudicial impact on the outcome of the jury decision process. The present research adopted an attributional analysis in order to examine the extent to which the types of legal reform affect social perception of the victim as well as the conviction rate in a videotaped consent defense rape trial. A large-scale jury simulation experiment was conducted with qualified jurors from the Minneapolis-St. Paul metropolitan area. Jurors either viewed an Improbable or Probable Likelihood of (victim) Consent version of the trial, with admission of prior sexual history evidence governed by one of three types of exclusionary rules. The results lend credence to the reformist contention that a rape victim is “on trial” along with the accused. Jurors were reluctant to convict when any testimony about prior sexual history was introduced. Moreover, jurors' close scrutiny of the victim's credibility and moral character was directly related to the conviction rate. Only the most restrictive evidentiary rule, when applied to an Improbable Consent case, curtailed the inference of victim consent, enhanced victim credibility, and increased the likelihood of conviction. Some of the legal and attributional implications of these findings were discussed.     

Health habits and depression in adolescence

In a study of the relationship between health habits and depression, 80 high school students, selected on an availability basis, were administered a Health Behaviors Questionnaire (HBQ) and the Beck Depression Inventory (BDI). The HBQ and the BDI significantly correlated (r=0.43p<0.01). Those who smoked were more frequently depressed than those who did not (X ²=10.5p<0.05), and those who used drugs other than marijuana were depressed more frequently than those who did not (X ²=9.2p<0.01). Mildly overweight boys (overweight by more than 5% of their ideal weight) and mildly under-weight boys (underweight by more than 5% of their ideal weight) were moreThis research was supported in part by a grant from the American Diabetes Association and by National institute of Health Grant MH 15529.Received his M.D. at George Washington School of Medicine. Major interest is interface of child psychiatry and pediatrics.Received his M.D. at Downstate Medical Center, State University of New York. Major interest is metabolic changes in adolescence.Received her M.A. from Queens College, New York. Major interest is measurement of human behavior.Received his M.D. from the University of Wisconsin. Major interest is adolescent sexuality.Received her Ph.D. in psychology from Hofstra University. Major interest is evaluation of clinical programs. depressed than boys of normal weight (p<0.02). The more pounds underweight the girls were, the more depressed they were (r=0.482, p<0.05). The closer the weight of a girl who perceived herself as overweight was to her ideal weight, the more depressed she was (r=–0.428,p<0.05).     

School return among pregnant adolescents

School return by adolescent mothers has been problematic. Many of the barriers to continuing education have been created by school system practices and policies. Recent administrative and court decisions are forcing changes in these traditional practices. Participants in an adolescent pregnancy program were permitted to attend their usual high school during and after pregnancy. Staff members discussed this and other educational opportunities with each eligible student and her family. More members of the program than control group reported some school attendance during the quarter of the delivery. Compared with the control group, which was permitted but not systematically encouraged to return, more program participants returned to day school following the pregnancy. Unexpectedly high rates of return to other school programs (other than day school) were reported by members of the control group. It is argued that the program effects are primarily a function of elimination of school system barriers, both formal and informal, to school return so that the subjects' already high motivation to return could be realized.Received her Ph.D. in sociology from the University of Washington. Main interests include social pathological aspects of fertility and fertility-related behavior.Received his Ph.D. in sociology from University of Washington. Main interests include sociology of the family. Current research is in family structure and suicide.