Analysis of dyes in illicit pills (amphetamine and derivatives)

The determination of dyes present in illicit pills is shown to be useful and easy-to-get information in strategic and tactical drug intelligence. An analytical strategy including solid-phase extraction (SPE) thin-layer chromatography (TLC) and capillary zone electrophoresis equipped with a diode array detector (CZE-DAD) was developed to identify and quantify 14 hydrosoluble, acidic, synthetic food dyes allowed in the European Community. Indeed, these may be the most susceptible dyes to be found in illicit pills through their availability and easiness of use. The results show (1) that this analytical method is well adapted to small samples such as illicit pills, (2) that most dyes actually found belong to hydrosoluble, acidic, synthetic food dyes allowed in the European Community, and (3) that this evidence turns out to be important in drug intelligence and may be assessed into a Bayesian framework.     

Analytical aspects of volatile substance abuse (VSA)

Through a case report, the authors illustrate the volatile substance abuse (VSA) toxicological investigation difficulties mainly due to evaporation of the compounds from postmortem samples and to the lack of reference data for interpretation. A 17-year-old man, student in a chemistry institute, was found dead with a plastic bag placed over his head. Several chemical substances were found in his belongings. Autopsy findings included serious pulmonary lesions and hemorrhagic digestive ulcerations. A large screening of drugs and toxic compounds and selective analyses for several classes of drugs of abuse were carried out in the autopsy samples. In particular, a headspace (HS), -gas chromatography/-mass spectrometry (GC/MS) technique was used to screen for volatile substances and metabolites in the biological samples and for residues of volatile substances on the surface of the plastic bag and in the chemicals found on the scene. The main analytical finding was the presence of alkanes (heptane, methyl-2-pentane, methyl-3-hexane, methylcyclohexane) in the gastric content. The literature data, VSA practices, long time-delay between death and autopsy, preservation conditions of the biological samples before analysis, and in-lab experiments on evaporation of volatile substances were considered to interpret this result. The present fatality was attributed to VSA with a gasoline-based stain remover like "eau écarlate," associated with a hypoxic recreation practice using a plastic bag.     

Anguish and despair in adolescents with eating disorders--helping to manage suicidal ideation and impulses

Adolescents struggling against anorexia nervosa or bulimia nervosa often experience self-punishing thoughts and behaviors, including self-mutilation, and suicidal ideation and attempts. These arise out of the profound anguish and despair frequently experienced by these young people. This paper outlines four particularly salient clinical themes underlying this despair that have significant implications for treatment. A practice perspective is discussed which emphasizes empathic listening and the development of a strong therapeutic alliance with the adolescent. Treatment recommendations draw from narrative theory and practice, and from feminist perspectives. The paper also draws on cognitive therapy and on recent developments in the areas of spirituality and motivational enhancement. Involving the distressed adolescent's family is also addressed.     

Sweden

European Journal of Political Research -     

Alterable electorates in the context of residential mobility

In some circumstances, politicians set about altering the composition of their electorate with a view to increasing their chances of being re-elected. A hypothesis along these lines is formulated in the context of local elections and residential mobility. Although the hypothesis is general, an assessment of its validity implies auxiliary assumptions related to a specific spatio-temporal context. That is done with reference to conditions prevailing in post-war French metropolitan areas. In the empirical part of the paper, some of the implications are submitted to tests on demographical and political data. On the basis of the tests, and although alternative explanations of the findings are possible, the hypothesis can be said to be corroborated.Earlier versions of this paper were presented at the 1986 Meeting of the European Public Choice Society and at the 1986 Journées de Microéconomie Appliquée. We are grateful for the comments and suggestions made on these occasions or independently by Jean Bénard, Albert Breton, Giorgio Brosio, Gérard Charreaux, Louis Duquesne de la Vinelle, Gianluigi Galeotti, François Gardes, Roger Guesnerie, Jean-Dominique Lafay, Claude Meidinger, Bernard Nonat, Werner Pommerehne, Alain Wolfelsperger, and an anonymous referee. Any remaining errors and shortcomings are our sole responsibility. We also thank the Institut de Mathématiques Appliquées for research support.     

L'émergence d'une discipline scientifique. La création de l'Association Suisse de Science Politique (1951‐1959)

This article presents the results of a historical research on the creation of the Swiss Political Science Association in 1959. A first attempt of creation had failed eight years before, despite a favourable international context and the important scientific work of Marcel Bridel. Although Bridel was supported by several leading figures of the early political science, his proposal was met by the hostility of his colleagues, who had a historical, philosophical or juristic background. On the other hand, a few years later Jacques Freymond managed to create the Association in an almost administrative way and without any scientific discussion. The contrast between these two attempts illustrates the ambivalence of the institutionalisation process of Swiss political science since 1959. The institutional logic was more important during the creation of the Association than the scientific dimension, but has nonetheless been a useful basis to promote further scientific efforts. This initial ambivalence has had durable effects on the discipline, which obtained academic legitimacy without clearly taking position neither on its basic object, nor on its specificities with respect to the other social sciences or even ordinary discourses on politics. This has led to a disciplinary identity that is contingent, uncertain and fragile, and which calls for an epistemological reconsideration of the intellectual autonomy of political science.     

From evaluation to auditing and from programs to institutions: Causes and consequences of the decline of the program approach

In the wake of the “audit revolution” during the 1980s and 1990s, administrative systems across the western world have tended to gradually downplay evaluation as a component of the policy process. At the same time, auditing has dramatically increased in scope and depth, and has also, to some extent, come to fill the role in policymaking previously played by evaluation studies. This article reviews this development from the perspective of policymaking and institutional change or “drift.” Specifically, we look at the types of information and knowledge that are lost and gained as a result of these developments. We apply a cross‐national approach, drawing on the examples from the European and North American contexts.