Monitoring of Levamisole Concentration in Serum of Traffic Participants after Cocaine Consumption

This study highlights the problem of levamisole‐adulterated cocaine in context of active traffic participation. For the purposes of levamisole concentration monitoring in human serum, an analytical method based on LC‐MS/MS and solid‐phase extraction was applied. A Luna 5 μm C18 (2) 100 A, 150 mm × 2 mm column and a mobile phase consisting of A (H₂O/methanol = 95/5, v/v) and B (H₂O/methanol = 3/97, v/v), both with 10 mM ammonium acetate and with 0.1% acetic acid (pH = 3.2), were used. The validation experiments demonstrated that the method applied was appropriate for levamisole quantification in human serum. For 23% of levamisole‐positive samples, the concentrations exceeded 20 ng/mL. Therefore, the interaction of this drug with cocaine has to be considered as important for active traffic participation. As a consequence, monitoring of levamisole concentration in human serum is recommended, as long as it is used as cocaine adulterant.     

Understanding the Roles of Context,Frequency, and Quantity of Alcohol Consumption in Child Physical Abuse: Risks for Mothers and Fathers

Alcohol use is related to child physical abuse, although little is known about gender-specific risks factors. This study examines the relationships between alcohol outlets, context-specific drinking, dose–response drinking and child physical abuse for mothers and fathers. Telephone interviews were conducted with 1973 female and 1050 male respondents in 50 California cities. Weighted negative binomial models were used to calculate the frequency of physical abuse in the past year. Drinking more often at restaurants was related to higher frequency of physical abuse for fathers, while mothers who drank more frequently at bars and parties used physical abuse more often. There were no significant dose–response drinking relationships for fathers. Drinking higher amounts at bars, parties, and restaurants was associated with less frequent physical abuse for mothers. Our findings suggest that a focus on drinking contexts may reveal heightened risk for many mothers who do not consume large amounts of alcohol.     

Perceived accountability and public attitudes toward local police

Recent national events have brought the issue of police-community relations into the public eye. Even though a large body of academic research exists on the predictors of public attitude toward police, very little is known about how public perceptions of police accountability influence satisfaction with the police. This study seeks to fill that gap by using ordered logistic regression and multi-year community-level survey data from one Western city (n = 3725) to examine the relationship between satisfaction with police accountability and overall attitudes toward the police. The results indicate that respondent satisfaction with police accountability was a strong, consistent predictor of satisfaction with local police, even after controlling for other important variables, such as race/ethnicity and community context. The findings suggest that public perceptions relating to the control of police officer conduct should be considered when assessing the predictors of attitudes toward the police.