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Monitoring of Levamisole Concentration in Serum of Traffic Participants after Cocaine Consumption 下载免费PDF全文
Marek Dziadosz Ph.D. Michael Klintschar Prof. M.D. Jörg Teske Ph.D. 《Journal of forensic sciences》2016,61(Z1):S250-S251
This study highlights the problem of levamisole‐adulterated cocaine in context of active traffic participation. For the purposes of levamisole concentration monitoring in human serum, an analytical method based on LC‐MS/MS and solid‐phase extraction was applied. A Luna 5 μm C18 (2) 100 A, 150 mm × 2 mm column and a mobile phase consisting of A (H2O/methanol = 95/5, v/v) and B (H2O/methanol = 3/97, v/v), both with 10 mM ammonium acetate and with 0.1% acetic acid (pH = 3.2), were used. The validation experiments demonstrated that the method applied was appropriate for levamisole quantification in human serum. For 23% of levamisole‐positive samples, the concentrations exceeded 20 ng/mL. Therefore, the interaction of this drug with cocaine has to be considered as important for active traffic participation. As a consequence, monitoring of levamisole concentration in human serum is recommended, as long as it is used as cocaine adulterant. 相似文献
74.
Geoff Edwards 《Australian Journal of Public Administration》2000,59(2):109-114
This essay examines ‘What is a policy?’ from the viewpoint of a public servant trying to make sense of the maze of official statements, procedures, guidelines and various other expressions of intra‐governmental opinion that might bear upon a discretionary decision. It seeks to clarify the meaning and status of policy, to explain how to determine cases which are not covered by explicit statements of policy, and to decide how much relative weight to accord to various policy documents and circumstances. Although it does not set out to rehash the old debate about the distinction between politics and administration (often misunderstood as a distinction between policy and administration), it finds Woodrow Wilson's 1886 aphorism on this subject a good place to start. 相似文献
75.
Prof. Dr. Anke Hassel 《Politische Vierteljahresschrift》2010,51(1):95-117
In the literature on welfare state reforms, continental welfare states like Germany have been considered to be resistant to reform. However, recently scholars started to argue that new reform coalitions and policy learning have led to a major restructuring of the German welfare state. In this article we introduce a third argument into the debate and claim that the recent reforms can only be understood by taking into account the specific structure of welfare state financing in Germany. Focusing on the reform of unemployment benefits we show that the crisis of the widespread cost-shifting practice between the federal budget, the social insurance and local authority budgets contributed to fiscal problems which could ultimately only be resolved by engaging in a fundamental restructuring of the financing architecture of welfare provisions for the long-term unemployed. 相似文献
76.
Prof. Dr. Christoph Knill Kai Schulze M.A. Dr. Jale Tosun 《Politische Vierteljahresschrift》2010,51(3):409-432
Policy change is an important concept in comparative policy analysis. Despite its central significance, most empirical studies fail to provide clear-cut definitions and measurement of this concept. Against this background, this article evaluates previous scholarship on policy change in the areas of social and environmental policy. We find that most studies use proxies for measuring policy change even though they contradict the basic idea of policy-making activities. Furthermore, studies usually neither capture the complexity of policy change, nor take into the possibility of policy change through dismantling account. Additionally, the empirical focus of most analyses is too narrow, thereby impeding robust statements about causality. In response to these shortcomings, we propose a new conceptual perspective, which captures policy change as a broader empirical phenomenon. We discuss its advantages as well as its disadvantages and show the implications for the research process. 相似文献
77.
Prof. Dr. Philip Manow 《Politische Vierteljahresschrift》2010,51(3):433-455
This article looks at how candidate votes have been translated into district mandates in the plurality tier of Germany’s mixed electoral system in all Bundestags-elections since 1953. Two questions in particular are addressed: How has disproportionality changed over time? And: What are the main determinants of disproportionality? To answer these two questions the article employs a modified version of the cube rule that accounts for the fact that the number of district parties in a mixed electoral system is higher than in a pure majoritarian system. The article identifies the effective number of district parties as the most important determinant of the disproportional translation of candidate votes into district mandates, i. e., the higher the number of district parties, the less proportional the translation. 相似文献
78.
Junior-Prof. Dr. Christoph Hönnige Prof. Thomas Gschwend Ph.D. 《Politische Vierteljahresschrift》2010,51(3):507-530
This article argues that the Judicialization hypothesis as a dominant research paradigm in the literature on the Bundesverfassungsgericht leaves out a number of relevant aspects. Rather, the court should be understood as being embedded in an area of competing interests among government, opposition, courts, litigating citizens and public opinion. The article identifies the institutional links between actors and relevant research questions. Finally, it discusses the theoretical, methodological and empirical challenges for further research on the Bundesverfassungsgericht. 相似文献
79.
This paper examines the impact of constitutional barriers on the privatisation of public utilities in 21 OECD-countries between 1980 and 2009. We present new and improved indicators for privatisation and constitutional barriers. Three empirical findings stand out: First, national privatisation trajectories differ across both countries and sectors. Second, there is a significant cross-national variation in terms of constitutional provisions related to public utilities which, thirdly, constitute important impediments to privatisation. 相似文献
80.
Analyzing and Interpreting Lime Burials from the Spanish Civil War (1936–1939): A Case Study from La Carcavilla Cemetery 下载免费PDF全文
Eline M. J. Schotsmans Ph.D. Almudena García‐Rubio M.Sc. Howell G. M. Edwards Ph.D. Tasnim Munshi Ph.D. Andrew S. Wilson Ph.D. Luis Ríos Ph.D. 《Journal of forensic sciences》2017,62(2):498-510
Over 500 victims of the Spanish Civil War (1936–1939) were buried in the cemetery of La Carcavilla (Palencia, Spain). White material, observed in several burials, was analyzed with Raman spectroscopy and powder XRD, and confirmed to be lime. Archaeological findings at La Carcavilla's cemetery show that the application of lime was used in an organized way, mostly associated with coffinless interments of victims of Francoist repression. In burials with a lime cast, observations made it possible to draw conclusions regarding the presence of soft tissue at the moment of deposition, the sequence of events, and the presence of clothing and other evidence. This study illustrates the importance of analyzing a burial within the depositional environment and taphonomic context. 相似文献