Human susceptibility to complex diseases. Genetic analysis in large populations]

Inherited susceptibility underlying the ethiopathogenity of complex diseases is based on the existence of a high number of genetic variants which are cooperating to generate different risk genetic profiles. We try to identify such profiles and construct wide data bases with this genetic information.     

The Future Of BRICS

正As the BRICS group enters its second decade,the collective is now ready to consolidate its early achievements.In this context,the leaders of Brazil,Russia,India,China,and South Africa met virtually on September 9 for their13th summit under India's chairship,themed Cooperation for Continuity,Consolidation and Consensus.     

Populism in latin America

Studies in Comparative International Development -     

microRNA Detection in Blood,Urine, Semen,and Saliva Stains After Compromising Treatments

Evaluation of microRNA (miRNA) expression as a potential method for forensic body fluid identification has been the subject of investigation over the past several years. Because of their size and encapsulation within proteins and lipids, miRNAs are inherently less susceptible to degradation than other RNAs. In this work, blood, urine, semen, and saliva were exposed to environmental and chemical conditions mimicking sample compromise at the crime scene. For many treated samples, including 100% of blood samples, miRNAs remained detectable, comparable to the untreated control. Sample degradation varied by body fluid and treatment, with blood remarkably resistant, while semen and saliva are more susceptible to environmental insult. Body fluid identification using relative miRNA expression of blood and semen of the exposed samples was 100% and 94%, respectively. Given the overall robust results herein, the case is strengthened for the use of miRNAs as a molecular method for body fluid identification.     

Introducing Purchaser/Provider Separation in the Catalan Health Administration: A Budget Analysis

This article examines the extent to which the Catalan reform launched in 1990 effectively introduced the purchaser/provider separation within the public health administration. The reform had two formulation sources: a law passed by the Catalan Parliament, which left this principle vague, and a further 'new public management' discourse, which interpreted the law in terms of a clear purchaser/provider separation. This study uses Dunleavy's (1991) analytical model of agency types to compare the impact of the reform on the budget structures of the health administration agencies affected — namely, the Department of Health and Social Security, the Catalan Health Service and the Catalan Health Institute. The data show that while the provider role was clearly defined and implemented, the purchaser role was not. Instead, the role of the health authority embodied the complex blend of functions established by the text of the law, which was also reflected in its budget structure, and which blurred the separation between purchaser and provider.     

The role of information asymmetry in the market for university–industry research collaboration

This study concerns the market for research collaboration between industry and universities. It presents an analysis of the population of all Italian university–industry collaborations that resulted in at least one international scientific publication between 2001 and 2003. Using spatial and bibliometric analysis relating to scientific output of university researchers, the study shows the importance of geographic proximity in companies’ choices of university partner. The analysis also reveals inefficiency in the market: in a large proportion of cases private companies could have chosen more qualified research partners in universities located closer to the place of business.     

The political economy of the European customs classification

Customs classification is an important element in a country's trade policy. How a good is classified can affect the rate of duty that applies, the coverage of non-tariff barriers, and the formulation and application of rules of origin. Reclassifications can occur because of the introduction of a new product, but also because of protectionist motives. This paper is the first attempt at explaining these reclassifications. Focusing on the European Union, I examine whether the number of tariff lines in an industry result from the introduction of new products or from protectionist lobbying. The analysis focuses on 90 manufacturing industries over 12 years. Results suggest that protectionist lobbying does play a role in explaining changes in the EU's customs classification.