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431.
Political polarization at the elite level is a major concern in many contemporary democracies, which is argued to alienate large swaths of the electorate and prevent meaningful social change from occurring, yet little is known about how individuals respond to political candidates who deviate from the party line and express policy positions incongruent with their party affiliations. This experiment examines the neural underpinnings of such evaluations using functional MRI (fMRI). During fMRI, participants completed an experimental task where they evaluated policy positions attributed to hypothetical political candidates. Each block of trials focused on one candidate (Democrat or Republican), but all participants saw two candidates from each party in a randomized order. On each trial, participants received information about whether the candidate supported or opposed a specific policy issue. These issue positions varied in terms of congruence between issue position and candidate party affiliation. We modeled neural activity as a function of incongruence and whether participants were viewing ingroup or outgroup party candidates. Results suggest that neural activity in brain regions previously implicated in both evaluative processing and work on ideological differences (insula and anterior cingulate cortex) differed as a function of the interaction between incongruence, candidate type (ingroup versus outgroup), and political ideology. More liberal participants showed greater activation to incongruent versus congruent trials in insula and ACC, primarily when viewing ingroup candidates. Implications for the study of democratic representation and linkages between citizens’ calls for social change and policy implementation are discussed.  相似文献   
432.
While it is recognized that veterans have increased rates of depression, post‐traumatic stress disorder (PTSD), suicide, and substance use disorders, rates of homicide and unintentional injury deaths in veterans have been minimally investigated. We evaluated all non‐natural deaths in New Mexico veterans between 2002 and 2011 in comparison with non‐natural deaths among non‐veterans. We reviewed all decedents in New Mexico with a history of military service and investigated by the medical examiner, excluding natural deaths and deaths due to fall from standing height. The most common manner of death was unintentional injury (62%), most of these deaths due to motor vehicle accidents (29%) followed by unintentional overdose (26%). Suicide rates among veterans were consistently higher than the general population. The most common mechanism of suicide in men was gunshot wound (72%), and intentional overdose in women (49%). Services are needed for veterans that are tailored to all ages and both sexes.  相似文献   
433.
434.
Abstract. The purpose of this paper is to estimate popularity functions for the Portuguese Prime Minister, Government, Parliament and President using the ordinary least squares (OLS) and seemingly unrelated regressions (SUR) methods. The results indicate that: (1) popularity polls for the Prime Minister and Government are better explained by economic conditions than are similar polls for the Parliament and President; (2) unemployment is a significant variable determining popularity while inflation is not; (3) honeymoon effects are significant; (4) popularity deteriorates over consecutive terms.  相似文献   
435.
436.
This article focuses on certain noteworthy legislation and cases affecting medicine and law during the period September 1, 2001, to August 31, 2002. It does not attempt to discuss every case or piece of legislation, but instead seeks to summarize some of the more significant developments in this area of law.  相似文献   
437.
1,4-Dihydropyridines calcium channel antagonists (1,4-DHP CCAs) are photolabile and the products of their photodecomposition have no pharmaceutical activity. In our previous work we have presented a screening procedure for eleven 1,4-DHPs in plasma by LC-MS-MS using multiple reaction motoring. The laboratory process includes preparation and storage of stock solutions, plasma storage, solid-phase extraction, reconstitution of extracts and storage time in an autosampler for LC-MS-MS analysis. Prior to validation of the analytical procedure, we have tested the stability of these compounds by exposure to light. Methanolic solutions have been exposed to laboratory and UV light and the stability of the compounds in plasma was tested by exposure of spiked plasma samples to laboratory light at room temperature. Stability during freeze-thaw cycles and stability during 2 month storage at -20 degrees C have been tested as well. Products of photodecomposition have been identified after forced degradation and the degree of degradation has been quantified using LC-UV-DAD and LC-MS-MS, respectively. A 96% degradation after only 2h has been observed when solutions of nifedipine or nisoldipine were exposed to laboratory light in clear glass vials. In plasma samples degradation was 25% in only 2h for both compounds. The main degradation product was produced by oxidation of the dihydropyridinic ring resulting in the pyridine analogue that has been described as the first metabolite in the metabolic pathway. Only minor degradation was found for the other tested compounds after 2h light exposure in methanolic solutions. Furthermore, lercanidipine and nicardipine were also degradated by esterhydrolysis. Several additional minor degradation products were found for the other tested 1,4-DHPs, however, some of them could not be identified. Preconditions for storage and handling of plasma samples prior to and during analysis for 1,4-DHP CCAs are suggested in order to avoid photodecomposition of the analytes.  相似文献   
438.
In this population-level study, we analyzed how well changes in drug and alcohol use among homicide victims explained declining homicide rates in New York City between 1990 and 1998. Victim demographics, cause of death, and toxicology were obtained for all homicide (N = 12573) and accidental death victims (N = 6351) between 1990 and 1998 from the Office of the Chief Medical Examiner of New York (OCME). The proportion of homicide and accident decedents positive for cocaine fell between 1990 and 1998 (13% and 9% respectively); the proportion of homicide and accident decedents positive for opiates and/or alcohol did not change significantly. Changing patterns of drug and alcohol use by homicide victims were comparable to changing patterns of drug and alcohol use in accident victims, suggesting that changes in drug and alcohol use among homicide victims between 1990 and 1998 cannot solely explain the decline in NYC homicide rates.  相似文献   
439.
The tendency to view the self as a prototypic member of a group is thought to be at the foundation of many social psychological phenomena. Two opposing accounts of perceived prototypicality have been suggested in the psychological literature. The self-justification account portrays this as a defensive tendency that occurs in response to threatened group status. The self-enhancement account portrays this as a strategic tendency to associate the self with positively viewed groups. These competing views were tested using both a minimal group (Study 1) and a naturalistic group (Study 2). Both studies showed that perceived prototypicality increased with increasing group status. Moreover, the effect of status was moderated by group importance (Study 1) and behavioral choice (Study 2). Both interaction patterns supported the self-enhancement view, suggesting that people view themselves as prototypic group members when doing so will promote a positive identity. These findings contradict common statements in the social identity literature.  相似文献   
440.
The purpose of this case control study was to compare police officers (n = 106) from a large urban police force, charged with committing intimate partner violence (IPV) with officers who were not charged (n = 105), in order to identify risk factors for IPV. We also compared the frequency, type, and final disposition of IPV reports filed against police officers before and after the enactment of the 1994 Violence against Women Act (VAWA). Officers accused of IPV were more likely to be members of a minority, on the force more than 7 years and assigned to a high crime district. No major differences on intake baseline MMPI scores were noted between cases and controls. A significant increase in reports of IPV was noted after the enactment of VAWA; the rate changed from 0.2/100 to 1.2/100 person years, although there were too few pre-1994 reports to compare further. Most of the final dispositions of the cases resulted in cases closed due to unsupported testimony from victims. An erratum to this article is available at .  相似文献   
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