The Toxicology of Methadone‐Related Death in Infants Under 1 Year: Three Case Series and Review of the Literature

Methadone‐related fatalities occur rarely in infants under 1 year, with five confirmed cases in the literature. The interpretation of pediatric postmortem toxicology relies on adult data; however, infants have crucial physiological differences that may impact interpretation of results. Retrospective case review included scene investigation, interviews, autopsy, and NIH/CDC Sudden Unexplained Infant Death Investigation Reporting Form. Methadone levels were confirmed by liquid chromatography/tandem mass spectrometry (LC‐MS/MS). The fatal blood methadone levels in this case series ranged from 69 to 700 ng/mL. This review of the literature adds toxicological findings of three methadone‐related infant fatalities and reviews the current literature on methadone‐related death in infants under 1 year. With opioid use on the rise in today's society, forensic experts should have a high index of suspicion for the possibility of intentional or unintentional poisoning in infants.     

(Bloßes) Festhalten der Mietzinsfälligkeit im Räumungsvergleich gerichtsgebührenunschädlich

Die Formulierung im gerichtlichen Vergleich "Festgehalten wird, dass der monatliche Bestandzins … bis einschlie?lich 31. 12. 1998 betr?gt" bzw "dass die Bestandzinse jeweils am 1. eines Monats bei fünft?gigem Respiro zur Zahlung f?llig sind" führen zum Anfall einer Erg?nzungspauschalgebühr ausgehend (blo?) vom Zeitpunkt des Vergleichsabschlusses bis zum Stichtag (hier 31. 12. 1998) und nicht etwa ausgehend von einer mit dem Zehnfachen des Jahreswertes des Mietzinses ermittelten Bemessungsgrundlage).     

Civil service 2000: The coming crisis

The essay provides a comprehensive review of “the coming crisis.” Parts of the contribution not reprinted here provide some focus on appropriate policies for ameliorating what is in our future.     

Money,exports, government spending,and income in Peru, 1951–66

Most studies of open developing economies, such as Peru, have found the foreign sector's impact on the domestic economy is very great. This is usually true whether the vehicle for changes in income is monetary or real.¹ This study, following the basic models developed by Polak, Prais and Schotta, will attempt to explain short run changes in income in Peru using two different approaches: a monetary approach and an income approach.     

Detection of methadone in human hair by gas chromatography/mass spectrometry

Determination of methadone in human hair by gas chromatography/mass spectrometry was described. Helium as carrier gas, a 30-m bonded phase-fused silica DB-1 capillary column and splitless injection at 230 degree C temperature were used. The concentrations of methadone and its metabolites were measured in addition by radioimmunoassay (RIA). Both methods GC/MS and RIA showed the presence of methadone in human hair.     

Technology transfer: A taxonomic view

Interest in the notion of technology transfer has been gaining momentum during the last two decades. Technology transfer, however, has different meanings to different people. It may indeed have a variety of definitions to an individual. This paper is an attempt to define the field in its entirety and to delineate all its facets in a manner that is parsimonious yet discriminating. In other words it is an attempt to create a classification or taxonomy of technology transfer.