The presence of trace amines in postmortem cerebrospinal fluid in humans

The postmortem levels of biogenic amines in cerebrospinal fluid may represent a useful tool in defining some pathological conditions; no information is available concerning the occurrence of trace amines in postmortem cerebrospinal fluid. Thus, the occurrence of octopamine, synephrine and tyramine were evaluated by using a HPLC system in 20 postmortem samples of cerebrospinal fluid (obtained from 11 males and 9 females) and their levels were compared with those of 20 living subjects (obtained from 11 males and 9 females). The results show that trace amines dramatically increase in the postmortem cerebrospinal fluid (100, 20, and 4 fold increase for tyramine, octopamine, and synephrine respectively). To our knowledge, our data represent the first time trace amines have been identified in postmortem cerebrospinal fluid and the dramatic increase observed for tyramine has the potential of becoming a new tool in forensic science for better defining the time of death.     

Assessment of exposure to opiates and cocaine during pregnancy in a Mediterranean city: preliminary results of the "Meconium Project"

For the first time in Europe, the "Meconium Project" aimed to estimate the prevalence of drug use by pregnant women and the effects of exposure to illicit drugs during pregnancy on the fetus and infant. Between October 2002 and February 2004, 1151 (79%) dyads among the 1439 mother-infant dyads from the Hospital del Mar, Barcelona, Spain, met eligibility criteria and agreed to participate in the study. We present preliminary results on the first 830 meconium samples and 549 mother-infant dyads, for which statistical analysis of socio-economic and demographic characteristics and newborn somatometry was completed. The meconium analysis showed an overall 7.9% positivity for drugs of abuse, with 6-monoacetylmorphine and cocaine being the analytes, most frequently found in samples positive for opiates and cocaine. Structured interview disclosed 1.3, 1.8 and 1.3% of mothers exposed to opiates, cocaine and both drugs, while only one mother declared ecstasy consumption. Meconium analysis showed that prevalence of opiates, cocaine and combined drugs exposure was 8.7, 4.4 and 2.2%, respectively, and confirmed the case of ecstasy use. Arecoline, the main areca nut alkaloid, was found in meconium specimens from four Asiatic newborns, whose mothers declared beetle nut consumption during pregnancy. Parental ethnicity was not associated with drug use, nor was the social class, although a higher tendency toward drug consumption was observed in professional and partly skilled mothers. Drug consuming mothers showed a higher number of previous pregnancies and abortions (p<0.05) when compared to non-consumer mothers (meconium negative test), probably due to a lack of family planning. Consumption of opiates and cocaine during pregnancy was associated with active tobacco smoking, a higher number of smoked cigarettes and cannabis use. Exposure status and smoking behavior correlated with significantly lower birth weight in newborns from mothers exposed only to cocaine and to opiates and cocaine simultaneously. Of the four newborns exposed to arecoline, one showed a low birth weight, low intrauterine growth, hyporeflexia and hypotonia.     

Military Criminal Procedures and Judicial Guarantees: The Example of Switzerland

Since the Nuremberg and Tokyo Trials, scant attention has beendevoted to military tribunals. Only with the creation of theICTY and the ICTR has civil society started reconsidering thequestion of which fora might be better suited for trying individualsresponsible for war crimes and other gross human rights violations.The aim of this paper is to illustrate the Swiss military judicialsystem. It analyses, on the one hand, the judicial guaranteesprovided for in the Swiss Military Penal Code and the Code ofMilitary Penal Procedure. On the other hand, it discusses thejudicial guarantees afforded in the only two war-crimes trialsheld by the Swiss military justice — the G case and theNiyonteze case — which involved civilians with foreignnationality. Finally, the paper argues against the abolitionof military judicial systems.     

Decentralisation and local governance in Mozambique: the challenges of promoting bottom-up dynamics from the top down

Since the conclusion of the peace accords in 1992, Mozambique has undergone several changes in the field of governance and institution-building. One key aspect of such reforms, strongly promoted by donors in peace-building contexts, has been the agenda of decentralisation and local governance, which has entailed political devolution in selected municipalities, and deconcentration and the creation of local councils in the rural districts. This article examines this agenda and its implementation focusing on two domains. First, it discusses the different interests that have shaped the political decisions taken on this agenda at the national level. Second, it examines the case of the local councils in the district of Angoche, critically debating the extent to which they epitomise the increase of local representativeness and, thus, whether or not they enhance bottom-up dynamics of governance. I argue that the limited effectiveness of such reforms in Mozambique reflect the inherent contradiction between the strong top-down dynamics that shape this process and the bottom-up effects that it aims to promote.     

Heteroqueer ladies: some performative transactions between gay men and heterosexual women

As theories of performativity struggle to disentangle and reconfigure the relationships between act and identity, a heterowoman who relishes the performance of femininity is still aware that she can be read as reactionary. Her choice of sexual partners seems to undermine the efficacy of similar strategies constructed by femme lesbians. One queer option for a heterosexual woman is to ‘act’ like a gay man. As more than one cultural commentator has pointed out, it appears that only a male drag queen can be a ‘lady’ these days. This particular woman does not want to change her biological sex to ‘be’ a gay man. She has learned how to be a ‘lady’ from the ‘feminized fags’ who may have learned from her mother. Their ironic distancing, camp connoiseurship, and parodic appropriation of the notion of a stable gender identity came as part of the package. As a result of this transaction, she acts as if she has balls under her dress. Such mimetic masquerades can be most easily recognized as resistant when performativity is ‘bound’ into a formalized performance. It is implicit that this artifice is not sustainable, nor is this desirable. ‘Doing’ queer means possessing the agency to defy and destabilize gendered behaviours, sexes, and sexualities through continuing and conscious decisions. This article explores the efficacy of heterosexual femme performances that attempt to challenge and subvert ideological normativities through their transactions with gay men.     

Breaking Down Barriers of Culture and Geography? Caring-at-a-Distance through Web 2.0

ABSTRACT

This article analyzes Join My Village (JMV), an NGO–corporation partnership that aims to “break down barriers of culture and geography” using the “power of online communities.” JMV uses Web 2.0 technologies to entice online users in the USA to engage with content about women’s lives in Malawi. Each time a user clicks on JMV content, the corporate partners donate money to the NGO. Using discourse analysis and interviews, I examine how JMV encourages users to care about distant others and with what effects. I draw attention to the use of Web 2.0 in the campaign in terms of how distant others become entangled in social media users’ everyday lives and the types of engagement JMV encourages. I conclude that while JMV offers some possibilities for caring-at-a-distance, the contradictory messaging and the corporate aspects of the campaign need more critical analysis.     

The Role of Risk in Improving Goal Setting in Performance Management Practices within Public Sector: An Explorative Research in Courts Offices in Italy

The study investigates whether the adoption of a risk-based approach that allows public managers to take into account the context and external not-controllable factors during goal setting may contribute to overcome unintended managerial side effects of performance management (PM) practices that hamper their success within public organizations. An explorative research is carried out on court officials of Italian public administration. The results from this study show that the adoption of a risk-based approach could enhance goal setting within the PM process and provide interesting insights to policy-makers invested of the responsibility to improve the effectiveness of current PM procedures.