Human herpesvirus-6 and sudden death in infancy: report of a case and review of the literature

Investigation of sudden death in infancy is a vital function of the medical examiner's office. Surveillance of these cases may lead to recognition of new diseases or new manifestations of previously described diseases. Human herpesvirus-6 (HHV-6) is a relatively newly described virus that has been recognized as a cause of acute febrile illness in early childhood. While most cases are apparently self-limited, seven fatal cases have been reported. We present a case of a seven-month-old Latin American male with recent otitis media and vomiting who was found dead in bed. Autopsy revealed interstitial pneumonitis with an atypical polymorphous lymphocytic infiltrate in the liver, kidney, heart, spleen, lymph nodes, and bone marrow, associated with erythrophagocytosis. Polymerase chain reaction (PCR) analysis of formalin-fixed paraffin-embedded tissue was positive for HHV-6 and negative for Epstein-Barr virus (EBV) and cytomegalovirus (CMV). HHV-6 was also detected in the atypical lymphoid infiltrate by in-situ hybridization.     

Changing Roles for a State Agriculture Department: Driving Forces and Organisational Responses in the 21st Century

This article examines the forces of change that have been operating on a state agriculture department over recent decades. These forces of change include pressures for the department to meet community expectations on issues such as animal welfare and ecological sustainability — issues which were not emphasised in its former focus on agricultural production. The article then goes on to look at the responses that have occurred in a public sector agency to these forces and what these may mean for the future of this traditionally conservative arm of government in terms of changes to what have been its primary client groups and its most important priorities.     

Resolving Reflection and Resolution in 3D Imaging of Fresh Bone

Structured light scanning is a noninvasive, accurate, and cost-effective 3D imaging technique, but due to reflection issues is yet to be utilized for tool mark analysis on fresh bone. During imaging, reflection from shiny surfaces, such as greasy bone, disrupts image formation. This study tested the David SLS-1 scanner's ability to image saw marks and explored six strategies to reduce reflection by [1] dulling the surface or [2] altering the projected light. The surface was dulled by freezing, talcum powder, dulling spray, or compressed air. The projected light was altered with a diffuser or limited to single pattern-coded. Results demonstrated that the resolution was insufficient for capturing minute details of striae. All six tests failed to reduce reflection sufficiently to produce complete images, but projecting vertical pattern-coded light showed the most promise. Future research is required concentrating on enhancing resolution and exploring the role of pattern-coded light in reducing reflection.     

Expert testimony about eyewitness identification

Recent research concerning eyewitness identification is surveyed with respect to its adequacy (reliability and validity) to support expert testimony. The conclusion is that the scientific basis is generally inadequate and that the more we have learned about various aspects of eyewitness identification, the most inadequate it appears. The argument is made that presentation in policy settings requires greater circumspection than would be required in presentation to scientific audiences. Prudential rules are suggested. They would have the effect of sharply reducing participation in the adversarial system.     

"The More Things Change…": Business Litigation and Governance in the American Automobile Industry

Business litigation is a relatively neglected area of corporate governance, particularly given its enormous rise in the United States over the past generation. As a preliminary effort to engage this issue, we examine dispute avoidance and resolution in the automotive sector since the early 1970s-focusing on relationships between auto manufacturers and their suppliers and dealers. We generally presume intercorporate litigation to be a "last resort" in business practice, chosen only on the breakdown of less costly means of dispute avoidance or resolution; we take such breakdown typically to be caused by shifts in the terms of competition among firms (e. g., increased competition, instability, uncertainty); and we expect that, over time, the costs of litigation will motivate efforts to construct new structures of nonlitigious dispute resolution. In the case of the U. S. auto industry, we find disruptive shifts in the terms of competition and increased recourse to litigation. Throughout, however, this litigation effect is mitigated by the dominance of major manufacturers over their suppliers and dealers. Over time, it is further dampened by industry development of mechanisms for arbitration or other nonlitigious dispute resolution.     

Autoamputation of the left arm--a bizarre suicide

A 24-year-old woman committed suicide by amputating her left arm immediately below the shoulder joint with a small kitchen knife. No references to such a suicide were found in an extensive literature search.     

Investigating forensic document examiners’ skill relating to opinions on photocopied signatures

Many forensic document examiners are hesitant to express authorship opinions on photocopied handwriting as the photocopying process results in less feature information than original writing. This study aimed to test the accuracy of 15 examiners' opinions regarding whether photocopied questioned signatures were genuine or simulated. Each examiner received the same set of original signature exemplars, from one individual, and a set of eighty questioned photocopied signatures comprising of genuine and simulated signatures. The overall misleading (error) rate for the grouped examiners' opinions was 0.9% providing strong evidence that examiners can make accurate observations regarding the authorship of non-original handwriting.     

Domains of competency to stand trial

Attempts to improve the clinical rigor of competency to stand trial evaluations have resulted in the development of several psycholegal measures. Among the most widely used of these measures are the Competency Screening Test (CST), the Fitness Interview Test (FIT), and the Georgia Court Competency Test—Mississippi State Hospital Revision (GCCT-MSH). To examine the theoretical domains of the competency construct as assessed by these measures, a series of exploratory factor analyses were performed combining previously reported data on the FIT and GCCT-MSH with a new outpatient sample of 353 court referrals. For the CST, data from a previous sample were compared to the original validation study. Of the three measures, only the GCCT-MSH showed evidence of stable, independent factors. A comparison of the GCCT-MSH to theDusky standard suggested a need to further develop empirical measures to better represent underlying constructs related to the defendant-attorney relationship and defendant's participation in his or her defense.     

Psychopathy in Youth: Pursuing Diagnostic Clarity

Psychopathy in youth has received increased recognition as a critical clinical construct for the evaluation and management of troubled adolescents (e.g., Frick, P. J. (1998). In Cooke, D. J., Forth, A. E., and Hare, R. D. (eds.), Psychopathy: Theory, Research and Implications for Society. Kluwer Academic Publishers, Boston, MA, pp. 161–187; Lynam, D. R. (1998). J. Abnorm. Psychol., 107: 566–575). To date, clinical research has examined psychopathy simply as a global construct rather than focusing on its specific criteria. In addition, researchers have tended to utilize downward extensions of adult conceptualizations of psychopathy to understand this syndrome in youth. This study was designed to assist in clarifying the construct of psychopathy in youth from a fresh perspective via prototypical analysis. Psychologists from the Clinical Child Psychology Section of the American Psychological Association (i.e., Division 53; N = 511) rated the prototypicality of the psychopathy construct for both male and female youth. Factor analyses for both genders resulted in 2 dimensions that reflected both personality and behavioral components of the disorder. Prototypicality ratings revealed important adult-to-child and male-to-female differences. In addition, child psychologists' views of their effectiveness at treating psychopathy in youth was surveyed. Contrary to the prevailing pessimism, clinical child psychologists reported that children and adolescents made moderate gains in psychotherapy. These results provide a framework for clinical child psychologists in their evaluations and treatment of psychopathic youth.