GC–MS analysis of eight aminoindanes using three derivatization reagents

Aminoindanes are a class of novel psychoactive substances (NPSs) that have become more prevalent over the past decade. GC–MS is often utilized for identifying seized drugs and is well regarded for its ability to separate mixtures. However, certain aminoindanes have similar mass spectral data and require specific gas chromatographic stationary phases for separation. Derivatization is an alternative method that can be applied to GC–MS to enhance chromatographic results, providing more selective analysis in seized-drug identification. This study investigates derivatization techniques to provide options for forensic science laboratories in accurately identifying aminoindanes. Three derivatization reagents, N-methyl-bis(trifluoroacetamide) (MBTFA), heptafluorobutyric anhydride (HFBA), and ethyl chloroformate (ECF) were evaluated for the analysis of eight aminoindanes by GC–MS using two common gas chromatographic stationary phases, Rxi®-5Sil MS and Rxi®-1Sil MS. All three derivatization methods successfully isolated eight aminoindanes, including the isomers 4,5-methylenedioxy-2-aminoindane (4,5-MDAI), and 5,6-methylenedioxy-2-aminoindane (5,6-MDAI) that could not be differentiated prior to derivatization. Reduced peak tailing and increased abundance were observed after derivatization for all the compounds, and mass spectra of the derivatives contained individualizing fragment ions that allowed for further characterization of the aminoindanes. This excluded 4,5-MDAI and 5,6-MDAI as they shared the same characteristic ions and were only distinguishable by their retention times. All three derivatization techniques used in this study allow for successful characterization of the aminoindanes and give forensic science laboratories flexibility in their analysis approach when they encounter these compounds.     

Autonomy in Extremis: An Intelligent Waiver of Appeals on Death Row

This article provides an in-depth account of the experiences of one condemned prisoner, Joseph Mitchel Parsons, who made the profound decision to waive his appeals and expedite his execution after serving eleven years under sentence of death in the State of Utah. Parsons determined that, at best, he faced years of appeals culminating in a long or life sentence that would likely end in a slow death in prison by unknown causes. Dropping his appeals, in contrast, offered a quick death in the execution chamber on a timetable under his control. The court granted Parsons the right to drop his appeals and expedite his execution. We provide evidence from this case study that the court allowed Parsons to make an autonomous decision to die on his own terms. As this research illustrates, an evaluation of the voluntariness of decisions to waive appeals in capital cases must be nested in an understanding of the death row experience of the individual under study. Case studies of the death row experience of those who waive their appeals, such as the research reported here, are integral to understanding these momentous decisions.     

A year in Bosnia: What was achieved

The challenges presented to the UN and the international community following the Cold War demand new responses and thinking with regard to peacekeeping operations. The situation in the former Yugoslavia provided a forum in which to develop a new approach to peacekeeping. The UN operated in a humanitarian role within a civil war, and a much greater level of enforcement was required than in other peacekeeping missions. The Security Council mandates defined the aspirations and limitations of the international community. Although at times the UN peacekeepers used high levels of force, it was not, and did not allow itself to be seen as, unacceptably partial or applying undue force. In a peacekeeping situation, there is still a clear need for a campaign plan to ensure cooperation between all organizations and the delivery of humanitarian aid. A UN mission cannot operate in a political vacuum; gains made on the security front will be lost if political momentum is not maintained.     

Mt. Laurel: Is it Based on Wishful Thinking?

“The people of New Jersey should welcome the result reached by the Court in this case, not merely because it is required by our laws, but, more fundamentally, because the result is right and true to the highest American ideals.” With these words Justice Pashman, in his concurring opinion, set forth the underlying assumption upon which the New Jersey Supreme Court based its decision to make the validity of municipal zoning dependent upon a new and complex standard. Mt. Laurel clearly establishes a new judicial standard for judging the validity of municipal zoning. However, whether that standard is likely to achieve its laudable objectives or whether its chances of success will be limited by political realities' that belie the noble ideals upon which the decision is based, remains to be seen.     

Experimental Intelligence

This article explores the use and application of experimental methodologies in intelligence analysis. Previous experimental work has much to tell us about how people process information in making judgments. Calibration, and how appropriate levels of confidence might be improved with systematic feedback, is addressed. Training around uncertainty biases is covered. Extant experimental work suggests mechanisms and tests which might be used to better screen potential analysts for personality characteristics that might make them more suited for some tasks over others. The paradigm of experimental manipulation serves as a useful template for exploring alternative conceptualizations of uncertain environments.     

Towards a Working Definition and Application of Social Age in International Development Studies

An emerging body of literature in childhood studies addresses the socially constructed nature of age that varies across time and place. However, despite the robustness of existing theory, few practitioners working in development contexts, where children and young people make up a large percentage of the population, consistently distinguish between biological facts of human development and the social meanings ascribed to different stages in the life cycle. Drawing on feminist theory and practical experiences of ‘gender mainstreaming’ in development studies, this article proposes and applies a working definition of ‘social age’ to supplement the prevailing focus on chronological age, embodied in legal definitions of ‘the child’.     

The Place of Vietnamese Marriage Migrants in Singapore: social reproduction,social ‘problems’ and social protection

While the literature on ‘global care chains’ has focused on the international transfer of paid reproductive labour in the form of domestic service and care work, a parallel trend takes the form of women marriage migrants, who perform unpaid labour to maintain households and reproduce the next generation. Drawing on our work with commercially matched Vietnamese marriage migrants in Singapore, we analyse the existing immigration–citizenship regime to examine how these marriage migrants are positioned within the family and nation-state as dependants of Singaporean men with no rights to work, residency or citizenship of their own. Incipient discussions on marriage migrants in civil society discourse have tended to follow a ‘social problems’ template, requiring legislative support and service provisioning to assist vulnerable women. We argue for the need to adopt an expansive approach to social protection issues, depending not on any one single source—the state, civil society and the family—but on government action to ensure that these complement one another and strengthen safety nets for the marriage migrant.     

The transfer of property rights by theft: an economic analysis

This article studies the voluntary transfer of property that had been stolen—a topic almost unexplored in the law and economics literature. The question is whether a buyer of a stolen good should obtain title to the good if he/she has purchased it in good faith. As described in the article different jurisdictions treat this issue differently. The traditional theory suggests that there is a trade-off between the costs of protecting the good and the costs of verifying the ownership. However, as shown, the rule of law concerning this issue significantly affects parties’ incentives. Specifically, it is shown that a rule of law where good faith is irrelevant in determining the issue of property rights Pareto dominates a rule where good faith may protect an innocent buyer. Thus, an owner of an asset will spend more resources on protecting his property and potential buyers will incur higher costs in order to verify the ownership when good faith is decisive for the transfer of property rights.