Evaluation of Suspected Counterfeit Pharmaceutical Tablets Declared to Contain Controlled Substances Using Handheld Raman Spectrometers

This study describes the performance of handheld Raman devices for determining whether suspect pharmaceutical tablets declared to contain controlled substances were consistent with authentic (CWA) or not consistent with authentic (NCWA) tablets using a simple, rapid, field-friendly method capable of being used by nonexperts. Twenty-five authentic products and 84 known NCWA tablets were examined using three “parent” devices for a total of 327 analyses. On average, the parent devices yielded a true pass rate of 100%, a true fail rate of 98.4%, a false pass rate of 1.6%, and a false fail rate of 0%. The methods/libraries were then transferred to 13 identical “daughter” devices, which were used to examine 10 suspect finished dosage forms in duplicate (six known NCWA tablets and four authentic tablets) for a total of 260 measurements. On average, the daughter devices had a true pass rate of 100%, a true fail rate of 95.5%, a false pass rate of 4.5%, and a false fail rate of 0.0%. These data demonstrate that the parent–daughter electronic transfer method was successful, which permits the ability to develop methods in the laboratory that can be seamlessly pushed out to field devices. The methods can then be used to (i) prioritize samples for additional testing using other more time-consuming laboratory-based techniques needed to detect and quantify active ingredients and (ii) help support the interdiction of dangerous tablets at ports of entry, thereby preventing them from reaching the supply chain.     

How do body-worn cameras affect the amount and makeup of police-initiated activities? A randomized controlled trial in Milwaukee,Wisconsin

Journal of Experimental Criminology - Examine how the amount and makeup of police-initiated activities changed after the introduction of body-worn cameras (BWCs). From May 21 to November 22, 2016,...     

Helping to Break the Glass Ceiling? Fathers,First Daughters,and Presidential Vote Choice in 2016

Political Behavior - Throughout her 2016 U.S. presidential campaign, Democratic Party nominee Hillary Clinton crafted messages intended to appeal to fathers of daughters and to highlight the...     

Learning from each other: causal inference and American political development

Public Choice - Within political science, a movement focused on increasing the credibility of causal inferences (CIs) has gained considerable traction in recent years. While CI has been...     

Productive specialization,peaceful cooperation and the problem of the predatory state: lessons from comparative historical political economy

Public Choice - This paper reconceptualizes and unbundles the relationship between public predation, state capacity and economic development. By reframing our understanding of state capacity theory...     

Measuring majority power and veto power of voting rules

We study voting rules with respect to how they allow or limit a majority from dominating minorities: whether a voting rule makes a majority powerful and whether minorities can veto the candidates they do not prefer. For a given voting rule, the minimal share of voters that guarantees a victory to one of the majority’s most preferred candidates is the measure of majority power; and the minimal share of voters that allows the minority to veto each of their least preferred candidates is the measure of veto power. We find tight bounds on such minimal shares for voting rules that are popular in the literature and used in real elections. We order the rules according to majority power and veto power. Instant-runoff voting has both the highest majority power and the highest veto power; plurality rule has the lowest. In general, the greater is the majority power of a voting rule, the greater its veto power. The three exceptions are: voting with proportional veto power, Black’s rule and Borda’s rule, which have relatively weak majority power and strong veto power, thus providing minority protection. Our results can shed light on how voting rules provide different incentives for voter participation and candidate nomination.

     

Federalism and university governance in Canada

There is increasing interest in how universities are governed, externally and internally (Austin and Jones 2016). Drawing on a comparative case study of the governance of six major Canadian universities and the literature, this article describes the impact of federal research and innovation policy and programs on universities and reflects on Ottawa's role. We suggest that the federal government participates in the external governance of universities, but in a way that differs significantly from provincial governments. Canadian federalism appears to be generally beneficial for university autonomy and examination of its operation sheds light on factors that enable universities to sustain their autonomy.     

Brexit populism and fantasies of fulfilment

Abstract

For Leave voters the Brexit referendum of 23 June 2016 was invested with hopes and dreams, of refound sovereignty and control, freedom and liberty, subjectivity and agency. Brexit was an opportunity for both new beginnings and a reclamation of British essences. Winning, however, has not provided the closure promised, and today Leave supporters often appear decidedly anxious and angry. Bringing together literature on ontological security with Lacanian understandings of the (always incomplete) nature of subjectivity, this paper provides an explanation of how it is that ’Brexit’ became invested with such high hopes of fulfilment, but also why the populist ’fantasies’ underpinning Brexit have inevitably fallen short. However, while closure around ontological security and subjectivity is impossible, the paper shows how the promise of fulfilment (and its inevitable failure) can be politically seductive and mobilizing, is a central strategy of populist politics, but as such is also one that is only likely to exacerbate the ontological anxieties and insecurities upon which populist politics preys.     

Does fertiliser use improve household welfare? Evidence from Ghana’s cocoa industry

This article analyses welfare impacts of fertiliser adoption using data collected from 838 cocoa farm households in the four key cocoa-producing regions in Ghana. Using propensity score matching (PSM), the study indicates that application of fertiliser leads to significant gains in farm yields, farm income, consumption expenditure, consumption expenditure per capita, and value of productive farm assets. The article concludes that cocoa-specific programmes such as Cocoa High Technology (Cocoa Hi-tech), initiated to intensify the application of improved farm technologies such as fertiliser, should be strengthened through effective and efficient management systems.