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41.
Munchausen syndrome by proxy (MSBP) is a special form of child abuse in which an adult repeatedly produces symptoms of illness in a person under his/her care. In most cases the perpetrators are mothers who repeatedly and in different ways produce or feign symptoms of illness in their children in order to obtain medical treatment for them. MSBP is thus a special form of child abuse that is also of importance in the field of forensic medicine and a particular challenge to the medicolegal expert. We report two cases of poisoning with different substances (clozapine and clonidine) detected by toxicological investigations at our Department of Legal Medicine. The relevance of the problem for the medicolegal expert and the importance of an interdisciplinary co-operation are pointed out. 相似文献
42.
Amniotic fluid embolism (AFE), a relatively rare complication in pregnancy, has a high mortality rate. We describe a case of a 38-week pregnant woman with such an embolism leading to almost immediate death after a blunt abdominal trauma inflicted in a motor vehicle accident and probably associated with improper positioning of a seat belt. It has been assumed that the pathophysiology of amniotic fluid embolism is related to an anaphylactoid reaction and that mast cell degranulation indicates this mechanism. Moreover, immunohistochemical antitryptase staining of pulmonary tissue samples in our case revealed mast cell degranulation. 相似文献
43.
Fatty acid ethyl esters (FAEE) can be used as alcohol markers in hair. It was investigated in this study whether this diagnostic method is disturbed by hair care and hair cosmetics. Traces of ethyl myristate, ethyl palmitate, ethyl oleate and ethyl stearate were detected in all of 49 frequently applied hair care products by headspace solid phase microextraction (HS-SPME) and gas chromatography-mass spectrometry (GC-MS). The highest concentration was 0.003% in a hair wax. From experiments with separated hair samples of alcoholics as well as from the evaluation of the FAEE concentrations and the data about hair care of 75 volunteers (alcoholics, social drinkers and teetotalers) follows that usual shampooing, permanent wave, dyeing, bleaching or shading are of minor importance as compared to the drinking amount and other individual features. However, false positive results were found after daily treatment with a hair lotion containing 62.5% ethanol, with a deodorant and with a hair spray. As an explanation, it is assumed that FAEE are formed in the sebum glands also after regular topical application of products with a higher ethanol content. 相似文献
44.
The article describes problems related to immunochemical screening-tests with special regard to benzodiazepines, which are commonly used for therapeutic purposes. Focal points are adulteration, manipulation and handling of samples, the selection of cut-off-values, specificity and cross-reactivity, influence of biotransformation and frequently observed pitfalls in the interpretation of the analytical results. 相似文献
45.
Kankaanpää A Meririnne E Ellermaa S Ariniemi K Seppälä T 《Forensic science international》2001,121(1-2):57-64
The 4-methylaminorex (4-MAX) is an amphetamine-related psychostimulant drug that has appeared on the clandestine market with a street name of "U4Euh". This compound exists as four stereoisomers, trans-4R,5R, trans-4S,5S, cis-4R,5S and cis-4S,5R, of which the cis forms have been classified as Schedule I substances in the US. The increasing variety of designer drugs has highlighted the importance of detection, identification, and quantitative measurement of these drugs, including 4-MAX, in biological samples. In the present study, the isomers of 4-MAX were detected in urine of rats treated with the drugs by some but not all of the on-site immunoassays tested, mainly as amphetamine or methamphetamine. To facilitate identification of 4-MAX by laboratories specialized in drug analysis, the electron-ionization mass spectrum and TLC data for underivatized 4-MAX using a routine laboratory drug-screening procedure is provided. In addition, a GC/MS method is described for the quantitative determination of cis- and trans-4-MAX as tert-butyldimethylsilyl-derivatives in plasma, urine and tissue. 相似文献
46.
Katainen Saara Räikkönen Katri Keskivaara Pertti Keltikangas-Järvinen Liisa 《Journal of youth and adolescence》1999,28(2):139-163
Development of depressive tendencies was assessed over a 9-year period in a random sample of 389 Finnish children. Predictors of maternal role satisfaction and hostile child-rearing attitudes, assessed when the children were ages 6 and 9 years, respectively, and a temperament predictor of perceived child difficultness, assessed when the children were age 6 years, were measured using questionnaires designed for this study. Depressive tendencies were assessed by a self-report at age 15 (modification of Beck's Depression Inventory). Using structural equation modeling, we tested a hypothesized model comprising direct as well as mediated effects between the childhood predictor variables and adolescent depressive tendencies. The results indicated support for a similar mediational model in girls and boys. Low maternal role satisfaction and maternal perceptions of child difficultness, measured when children were age 6 years, predicted hostile maternal child-rearing attitudes measured when children were age 9 years, which in turn had a significant direct effect on depressive tendencies among these children during adolescence. The only other direct effect was found solely in girls: Low maternal role satisfaction predicted adolescent depressive tendencies. These results underline the close interplay of child temperament and mothering factors in the development of depressive tendencies in girls and boys. 相似文献
47.
The authors describe 3 cases where Y-chromosomal systems were used for typing the biological traces. In the first case, a murder, for the major amount of cell material found on a dish towel (and analysed two years after the crime) female persons were excluded for the system amelogenin and Y-chromosomal systems. A brother of the victim could not be excluded for autosomal STR-systems. Upon confrontation with the results of the DNA-analysis (among other things), this brother confessed the murder of his sister some days later. He was found guilty by the court. In the second case described, a rape of two girls, many traces were analysed parallely with Y-chromosomal and autosomal PCR-systems. The objects where male DNA matching the suspect were found (a paper tissue, a sweat shirt and the knickers of the girls), also showed small amounts of alleles matching with the suspect for autosomal systems, while the major part in these systems was from the girls. The suspect was sentenced to many years imprisonment. In the third case, a possible rape of a young woman, a stained microscope slide of a vaginal swab had to be examined. Microscopically a few sperm heads could be seen in a surplus of leucocytes. The male proportion could be analysed only in the Y-chromosomal systems, not in the autosomal ones. For the frequency calculation of the Y-chromosomal allele combination the haplotype data bank of the Institute for Legal Medicine of the Humboldt university in Berlin was indispensable. 相似文献
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50.
Rechtsanwältin Dr. Sabine Wrede 《Natur und Recht》2005,27(1):28-31
Seit dem 7. 9. 2004 liegt ein weiteres Urteil des EuGH zum europäischen Abfallbegriff vor. Danach ist Benzin, das unbeabsichtigt in den Boden und das Grundwasser gelangt, ebenso als Abfall zu qualifizieren wie das verunreinigte Erdreich selbst. Nach Ansicht des Gerichtshofs spielt es dabei keine Rolle, ob der Boden nach der Verschmutzung ausgehoben worden ist oder nicht. Diese Rechtsprechung steht nicht länger im Einklang mit der ständigen Rechtsprechung deutscher Gerichte und wirft insbesondere mit Blick auf die fehlende Sonderrechtsfähigkeit nicht ausgehobenen kontaminierten Erdreichs Fragen auf, denen im folgenden Beitrag nachgegangen werden soll. 相似文献