Isolation of the DNA minisatellite probe MZ 1.3 and its application to DNA 'fingerprinting' analysis

A minisatellite probe, MZ 1.3, detecting hypervariable fragment patterns was isolated from a human genomic library. A repetitive sequence of 27 bp length was identified which is contained in the probe approx. 40 times. The MZ 1.3 repeat shows variable homology of 53-73% to the repetitive sequence of the protein III gene of the bacteriophage M13 genome. Polymorphic restriction fragment patterns were found with MZ 1.3 using the enzymes Hinf I, BstN I, Hae III, Mbo I, PstI/Pvu II, and Rsa I. An average of 18 polymorphic fragments was observed using Hinf I as enzyme. The band sharing frequency after Hinf I digestion among unrelated individuals was determined to be 23.8 +/- 7.2%. An example for the application of MZ 1.3 to paternity testing in an incest case is given. The probe can be used with radioactive or non-radioactive detection systems. An approach is presented to compare polymorphic fragment patterns from individuals obtained by independent gel runs on the basis of relative band positions (RBP) and calculated in a computerized analysis.     

Local law enforcement terrorism prevention efforts: A state level case study

Although law enforcement agencies across the nation have assumed part of the responsibility in the fight against terrorism, significant confusion exists as to the role of local law enforcement. While some agencies have taken steps towards terrorism prevention, little data has been collected on which agencies have taken the greatest steps, how those agencies have changed, and how other agencies should direct their activity. This case study of law enforcement census data from a single state considered variations in terrorism preparedness and predictors of preparedness. Agency size, presence of funding, and other variables significantly predict levels of terrorism preparedness. Important policy implications such as the distribution of funding and which agencies should be working towards terrorism preparedness are discussed.     

The Olson ratio and indirectly endogenous rent

Public Choice - We consider an economy where the rent value depends indirectly on value-adding investment of agents (thus indirectly endogenous) and the win-probability is a function of rent...     

Trade union behaviour and inter-regional variations in unemployment rates

An important problem in the political economy of the UK is that the disparity of unemployment rates across its regions is much more marked than the corresponding dispersion of wage rates. One possibility is that this is due to the attitude of trade unions to their members in different regions. If unions wish to preserve parity between members in different regions then they will value wage equality between regions over and above wage levels. This may then persuade them to overlook inter-regional productivity differences in setting wages. The price that low-efficiency regions will then pay for this desire for wage equality is higher unemployment rates.Much of the research for this paper was carried out while the author was visiting the Trade Union Economics Research Institute (FIEF), Stockholm in 1989. An earlier version of this paper was presented at a seminar there and the author is gratefully to Villy Bergstrom, Paul Chen, Douglas Hibbs, Eva Udden-Jondal and other institute members for several useful comments. Comments from Kevin Lee, John Spencer and an anonymous referee have also substantially improved the paper. The usual disclaimer applies.     

Sexual harassment in student residences: A response to DeKeseredy and Kelly's study

Research data from a recent study of sexual harassment in single student residences are provided as confirmation of DeKeseredy and Kelly's national study. The implications of data confirming the consistency of gender differences in attitudes towards and perceptions of unwanted sexual experiences are discussed. Future research in sexual harassment should focus on evaluating preventive education programmes and on operationalizing contextual factors that support sexual harassment.