Liver damage in rats during acute carbon monoxide poisoning

Plasma leucine aminopeptidase (LAP) levels and respiration rates of isolated liver mitochondria were studied in carbon monoxide (CO)-poisoned rats sampled at respiratory arrest. An increase in LAP levels paralleled a decrease in the respiratory control ratio and the $\text{ADP}\text{O}$ ratio. The results suggest that the damage to mitochondria closely correlates with the liver damage in rats during acute CO poisoning.     

Identification of Arrhythmogenic Right Ventricular Cardiomyopathy‐Causing Gene Mutations in Young Sudden Unexpected Death Autopsy Cases

Arrhythmogenic right ventricular cardiomyopathy (ARVC) results in an increased risk of sudden death. We sought mutations of desmoglein‐2 (DSG2), desmoplakin (DSP), and plakophilin‐2 (PKP2) in 15 cases of sudden death whose causes of death could not be determined at autopsy. In three victims, mutations were identified in DSP. Two of these mutations were novel; one had previously been reported in a patient with ARVC that had been diagnosed clinically. Histological findings were not typical of ARVC; however, it was notable that these mutations were present in three of 15 cases, a relatively high proportion. The causal relationship between the mutations and ARVC is unclear, but the mutations might have been associated with faulty desmosomal proteins resulting in fatal arrhythmia. Combining information gathered by the traditional means of gross and histological examination with postmortem genetic analysis of young victims would assist in identifying their cause of death.     

Corruption,interest rates and business cycles: comparison of emerging economies

We examine the hypothesis that corruption in a country negatively influences the macroeconomy through an increase in the country-specific interest rate (interest rate shock). An empirical study estimated the contribution of the interest rate shocks to the variance in output growth at 5.1% in Mexico within the framework of stochastic growth models for small open economies. We replicate this study with the same dataset and investigate which parameters affect the contribution of the interest rate shocks to business cycles. Then, we estimate the same model for different emerging economies to investigate the relationship between the corruption level and macroeconomic contribution of the interest rate shocks. For this purpose, we use Transparency International’s Corruption Perceptions Index (CPI) to measure the corruption level. Finally, we investigate the correlation between the CPI and the estimated series of the interest rate shock. Our findings are as follows. First, the average size of the interest rate shocks is positively associated with the contribution of these shocks to the variability of output growth. Second, the average size of the interest rate shocks is also positively associated with the corruption level. Third, the estimated interest rate shock and the corruption level are positively correlated with each other. As we treat the corruption level as an exogenous variable in the model, these findings lead us to accept the hypothesis. The “Appendix” further clarifies a well-known hypothesis that the cycle is the trend in an emerging economy.     

Systematic Quantitative Literature Review on Criminological Theories in Asia

Empirical work on criminological theories in Asia has been increasing. However, few comprehensive and systematic reviews on the application of criminological theories in Asia have been conducted. Using a systematic quantitative literature review method on peer-reviewed English-language journal articles, we aim to provide an overview of the use of five major criminological theories in Asia: (1) strain; (2) social learning; (3) control; (4) routine activity; and (5) developmental and life-course. In particular, we address the following four questions: (1) how often are these theories tested in which region of Asia?; (2) what methodology is used to test these theories?; (3) to what extent are these theories supported in the Asian context?; and (4) what cultural uniqueness in the Asian context is taken into account in testing these theories, and what role and effect do they play in analysis and outcome? Findings indicate that the relationship between these theories and the Asian regions is skewed; many studies do not employ rigorous methodologies; these theories are either fully or partially supported in the Asian context; and only a few studies have analyzed the cultural uniqueness of the Asian context, and no effect of cultural uniqueness of the Asian context was found. Research implications for developing criminology in Asia are discussed.