Postmortem molecular analysis in victims of sudden unexplained death

Among several conditions that can be responsible for sudden cardiac death (SCD), an important role is played by long QT syndrome (LQTS). LQTS is a congenital electric heart disease that can be asymptomatic or have very severe clinical manifestation, leading to cardiac arrest. In fact, the first manifestation of LQTS can be hyperkinetic ventricular arrhythmias. The presence of LQTS should be considered in all cases of SCD where autopsy is negative for anatomic and histopathological findings. In these cases, after an accurate anamnesis, a genetic screening should always be performed. The screening on LQTS genes is performed on DNA extracted from paraffin-embedded tissues. Making a proper diagnosis in such cases can help to find new affected subjects among the family members of SCD victims and treat them. In these cases, if the pathologist does not make a correct diagnosis, can he or she be sued for malpractice?     

Endogenous economic voting: evidence from the 1997 British election

Using panel surveys conducted in Great Britain before and after the 1997 general election, we examine the relationship between voting behavior and post-election economic perceptions. Drawing on psychological theories of attitude formation, we argue that those who voted for Labour and the Liberal Democrats perceived the past state of the British economy under the Tory government more negatively than they had prior to casting their ballot in the 1997 election. Similarly, we posit that Labour supporters would view the future state of the national economy under Labour more positively than they had before the election. This indicates that, contrary to many assumptions in the economic voting literature, voting behavior influences evaluations of the economy as voters seek to reduce inconsistencies between their vote choice and evaluations of the economy by bringing their attitudes in line with the vote they cast in the election. It also means that voters’ post-election economic perceptions are, at least in part, influenced by and thus endogenous to their vote choice. This finding has two major implications: first, cross-sectional models of economic voting are likely to overestimate the effect of economic perceptions on the vote. Second, the endogeneity of economic perceptions may compromise the quality of economic voting as a mechanism for democratic accountability.     

The Effect of Problem Severity,Managerial and Organizational Capacity,and Agency Structure on Intergovernmental Collaboration: Evidence from Local Emergency Management

Like most public managers nowadays, local emergency managers operate within complex, uncertain environments. Rapid changes in the scope and severity of the issues increase the extent of intergovernmental collaboration necessary to address such challenges. Using a large data set of county emergency management agency directors, variations in intergovernmental collaboration reflect influences from problem severity, managerial capacity, and structural factors. The results demonstrate that public managers who perceive problems as severe, possess specific managerial skills, lead high‐capacity organizations, and operate in less complex agency structures collaborate more often and more effectively across governmental boundaries.     

Kreditgewährung durch Kontoüberziehung und Kontoüberschreitung Neuregelung durch das Verbraucherkreditgesetz

Die §§ 18-24 des neuen Verbraucherkreditgesetzes enthalten – entsprechend den einschl?gigen Vorschriften der Verbraucherkreditrichtlinie – umfangreiche Konsumentenschutzbestimmungen für Kreditverh?ltnisse, die durch Kontoüberziehung und Kontoüberschreitung zustande kommen. Die wesentlichen Inhalte dieser Neuregelung im Vergleich zur früheren Rechtslage, ihr Anwendungsbereich und die Auslegung zweifelhafter Bestimmungen sind Gegenstand des folgenden Beitrags.     

Analysis of 11 tetrameric STRs in wild boars for forensic purposes

STR profiling of animal species has a wide range of applications, including forensic identification, wildlife preservation, veterinary public health protection and food safety. We tested the efficacy of a multiplex PCR-based assay including 11 porcine-specific tetrameric STRs in a population sample of wild boars (n = 142) originating from Piedmont (North West Italy). Multiple deviations from Hardy–Weinberg expectations were observed, mostly due to a reduction in observed heterozygosity indicative of a high degree of inbreeding. A value of θ of 0.046 and an inbreeding coefficient of 0.089 were estimated. Combined power of discrimination and probability of exclusion values for the STR panel were 0.9999999999996 and 0.99989. In order to test the suitability of the method for meat traceability purposes, a domestic pig reference sample (n = 412), consisting of commercial lines commonly used in the meat production process, was also typed. A Bayesian cluster analysis carried out using the observed genotypes, showed a percentage of correct subspecies assignment of individual samples of 0.974 for wild boars and 0.991 for pigs, thus demonstrating the usefulness of the multiplex STR-typing system for discrimination purposes.     

Evaluating Collaboration: The Solution to One Problem Often Causes Another

Collaboration has become the predominant approach to solving complex public problems. This choice, however, often is not driven by demonstrated effectiveness. Collaboration is instead chosen in the hope that a networked arrangement will be more effective than individual organizations working on the issue alone. Questions regarding collaborative effectiveness persist and constitute a significant challenge facing both public management practitioners and public administration scholars. In light of the case study in this issue of Public Administration Review by Maurits Waardenburg and colleagues, this article reviews the current thinking on the measurement of collaborative performance and discusses steps that professionals can take to evaluate the effectiveness of their collaborative endeavors.     

Can you hear me Major Tom? News,narratives and contemporary military operations: the case of the Italian mission in Afghanistan

This research explores the relationship between public narratives and the Italian military contribution to the International Security Assistance Force (ISAF) in Afghanistan (2001–2014). Despite attracting little attention in the literature, Italy has been one of the most crucial contributors of multilateral military missions around the world in the post-bipolar era. Italy has remained consistently engaged militarily in Afghanistan over the entire period of the ISAF mission. However, the country’s involvement has been characterised by differing and controversial views and perspectives among Italian political actors and the media. This study aims to reconstruct the core features of the strategic narratives and the media frames around the military intervention and it does so through a Qualitative Content Analysis on a collection of almost 200 articles published by four main Italian national newspapers. The goal of this paper is twofold: on the one hand, we systematically retrace the main discursive patterns and frames employed by the newspapers on the ISAF. On the other, we evaluate whether in the case of military interventions, the Italian media unveil critical inconsistencies and competitive arguments or whether they function as a repeater of the dominant political discourse. Thanks to the case study, we find that the Italian media supported the mainstream narratives.