Identification of alprazolam in hair in two cases of drug-facilitated incidents

The use of a drug to modify a person's behaviour for criminal gain is not a recent phenomenon. However, the recent increase in reports of drug-facilitated crimes (sexual assault, robbery) has caused alarm by the general public. Among the drugs that can be used, alprazolam (Xanax), an anxiolytic benzodiazepine, has been seldom observed. To document two cases involving this drug, we have developed an approach based on hair testing by LC-MS/MS. After pH 8.4 buffer incubation and extraction with methylene chloride/diethyl ether (80/20, v/v), hair extracts were separated on a XTerra MS C18 column using a gradient of acetonitrile and formate buffer. Alprazolam and diazepam-d5, used as internal standard, were detected by electrospray tandem mass spectrometry. In the first criminal case, alprazolam tested positive in two consecutive 2 cm hair segments at 4.9 and 2.4 pg/mg, from a 12-year-old girl, assaulted by her father who had sedated her three or four times. In the other case, alprazolam was detected in four consecutive 1cm hair segments at 3.1-0.4 pg/mg, obtained from an adolescent who had been forced to prostitute herself.     

Hydrogen: Fueling EU-Morocco Energy Cooperation?

The war in Ukraine and the looming threat of climate change are driving the strategic need to diversify sources of energy, including renewables. Therefore, the European Union aims to develop energy relations with non-EU member states, and Morocco has become a key priority. Both Brussels and Rabat are pursuing ambitious green policies and cooperation initiatives, including on hydrogen. Drawing on theories of international institutions and political economy, this article analyzes hydrogen-related relationship patterns and explains demand and supply factors as drivers of institutionalized energy cooperation. We examine the EU's hydrogen approach and development, its relations with Morocco, and the political interests of both sides. Our analysis shows that the complex interdependencies in the evolving EU-Morocco hydrogen relations indicate that demand can be met by supply. However, challenges remain, including the need to deepen the partnership and prepare the market for commercial hydrogen production.     

Le congrès mexicain mis en scène. 1813–72

SUMMARY

By looking at the various sites where successive Mexican congresses met between 1813 and the 1870s (be they constituent or legislative bodies), this article examines the role of such assemblies in the national political history and public culture of Mexico. The first part of this article follows the steps of successive congresses, identifying periods of serious political conflicts – though congress enjoyed a time of relative flourishing when it occupied a chamber within the National Palace. By analysing the ceremonies, rituals and symbols adopted by congresses, the second part of the articles underlines a historical rupture after 1857, which coincides with the laicization of government, and the secularization of the public space and parliamentary rituals.     

From adolescence to adulthood: Development of psychopathology in kibbutz and town subjects

The unique contribution of the National Institute of Mental Health—Israeli longitudinal high-risk study is the comparison of the development of children at high risk for schizophrenia from two divergent socialization environments: the Israeli urban nuclear family and the collective education in the kibbutz. The study began with 100 preadolescent children who were followed up into adolescence, with outcomes measured in their 20s and 30s. No difference in the prevalence of schizophrenia was found at the last follow-up phase, with subjects at an average age of 32, but a higher incidence of major depression was found in the kibbutz than in the urban high-risk group. The data suggest adolescence as the period in which the differential effects of environment began to appear. Environmental factors, related to the social structure of the kibbutz, which may have led to this outcome, are discussed.Received Ph.D. in psychology from the Hebrew University, Jerusalem. Engaged in research on socialization in the kibbutz as well as in the NIMH-Israel High-Risk project, and is a practicing psychotherapist.Member of Kibbutz Biet-QeshetAn educational psychologist practicing within the Jerusalem school system. Has taken a leading part in the fourth phase of the NIMH-Israel High-Risk Study and currently completing a doctoral dissertation in psychology.Received Ph.D. from Columbia University. Has served as Chief Scientist of the Ministry of Education of Israel. Involved in the NIMH-Israel High-Risk Study from its start and has served as the Israeli principal investigator during its fourth phase.     

Inclusive digital finance: the industry of equity crowdfunding

The Journal of Technology Transfer - Nowadays equity crowdfunding plays an important role in the entrepreneurial finance markets. To better understand the functioning of the industry, it is...     

La gestion axée sur les résultats: Comparaison des cadres de gestion de huit juridictions

Au cours des deux derniéres décennies, plusieurs gouvemements ont voulu réformer leur administration publique en mettant en place un cadre de gestion axée sur les résultats. Jusqu à tout récemment, la documentation scientifique n'abor‐dait que trés peu ce théme et, outre les travaux de l'OCDE, le concept de gestion axée sur les résultats et son contenu n' avaient pas été définis. Nous avons donc voulu éla‐borer une définition générique de la gestion axée sur les résultats et comprendre la façon dont elle s'intègre à différents aspects de la gestion des organisations. Pour ce faire, nous avons exploré le cadre de gestion proposé par les réformes mises de l'avant dans huit juridictions. Les pays et provinces canadiennes choisis ont une approche‐type de gestion anglo‐américaine, soit le Canada, le Québec, l'Ontario, l'Alberta, les États‐Unis, l'Australie, le Royaume‐Uni et la Nouvelle‐Zélande. Les modèles étudiés présentent plusieurs similarités. On observe que la gestion de la performance dans ces juridictions se déploie dans des cycles de gestion composés de plusieurs étapes. Les éléments communs de ces cycles sont la planification stratégique, la planification opérationnelle, la réalisation des plans et des programmes, la mesure ds résultats, la reddition de comptes et l'analyse et l'interpréta‐tion des résultats. Ces processus se concrétisent par la publication de documents. Par ailleurs, ces cadres de gestion ont tendance à s'intégrer aux autres enjeux de la gestion des organisations tels que la qualité du service à la clientèle, la gestion des res‐sources humaines et financières et la vérification. Abstract: Over the last two decades, several governments have wanted to reform their public administration by implementing a results‐based management framework. Until very recently, the scientific literature hardly addressed this issue and, other than the OECD work, the concept of results‐based management and its content had not been defined. We therefore wanted to develop a generic definition for results‐based management and to understand how it fits into various aspects of organizational management. To do so, we explored the management framework put forward through reforms introduced in eight jurisdictions. The countries and Canadian provinces chosen, i.e., Canada, Quebec, Ontario, Alberta, United States, Australia, United Kingdom and New‐Zealand, use the typical Anglo‐American management approach. The models considered have several similarities. We found that performance management in those jurisdictions was implemented throughout several steps of management cycles. Common elements in these cycles include strategic planning, operational planning, plan and program delivery, results measurement, accountability, and results analysis and interpretation. The process is documented through published documents. Moreover, these management frameworks tend to become part of the other organizational management components, such as quality of customer service, management of human and financial resources, and auditing.     

与达妮埃尔·萨乐娜芙的对话(英文)

<正>HUANG Hong:A l'occasion du centenaire de l'écrivain,vous publiez Castor de Guerre,un portrait de Simone de Beauvoir.Est-ce que ce livre dense pour vous est une dette de jeunesse     

作品的解构

<正>Lorsqu'apparaít un nouveau nom en littérature,la prudence voudrait qu'on laisse agir le temps pour en appréhender,si ce n'est la pérennité,du moins le sens et les effets sur