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81.
Nitsan?ChorevEmail author Kenneth?C.?ShadlenEmail author 《Studies in Comparative International Development (SCID)》2015,50(2):143-156
In this introduction, we review the literature on intellectual property rights and access to medicines, identifying two distinct generations of research. The first generation analyzes the origins of new intellectual property rules, in particular the World Trade Organization’s Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS), and the significance of TRIPS to developing countries. The second generation examines national-level experiences, as countries adjust their laws and practices to conform to TRIPS. Based on the insights provided by the articles in the special issue, we contribute to the second generation by considering a pair of overarching sets of issues. First, we highlight the domestic political challenges that affect how countries go about implementing their new obligations under TRIPS. We argue that alliances and coalitions are necessary to underpin the use of policy instruments designed to conform to TRIPS while taking into account local conditions and needs, and we present insights that allow us to understand why alliances and coalitions are difficult to construct and sustain in this area. Second, we explain why policies that many countries adopt in response to TRIPS often do not generate their desired or intended outcomes. In the last section of the introduction, we review the articles that appear in this special issue. 相似文献
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Terezie Cernosek B.S. Kevin E. Eckert M.Sc. David O. Carter Ph.D. Katelynn A. Perrault Ph.D. 《Journal of forensic sciences》2020,65(1):134-143
Volatile organic compounds (VOCs) are by-products of cadaveric decomposition and are responsible for the odor associated with decomposing remains. The direct link between VOC production and individual postmortem microbes has not been well characterized experimentally. The purpose of this study was to profile VOCs released from three postmortem bacterial isolates (Bacillus subtilis, Ignatzschineria indica, I. ureiclastica) using solid-phase microextraction arrow (SPME Arrow) and gas chromatography–mass spectrometry (GC-MS). Species were inoculated in headspace vials on Standard Nutrient Agar and monitored over 5 days at 24°C. Each species exhibited a different VOC profile that included common decomposition VOCs. VOCs exhibited upward or downward temporal trends over time. Ignatzschineria indica produced a large amount of dimethyldisulfide. Other compounds of interest included alcohols, aldehydes, aromatics, and ketones. This provides foundational data to link decomposition odor with specific postmortem microbes to improve understanding of underlying mechanisms for decomposition VOC production. 相似文献
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Anthony L. Burrow Amanda C. O’Dell Patrick L. Hill 《Journal of youth and adolescence》2010,39(11):1265-1273
While having a purpose in life has been theorized as a developmental asset, the extent to which adolescents cultivate a meaningful
sense of direction is not well understood. In the present study, cluster analysis was used to classify adolescents by levels
of purpose exploration and commitment. The sample (N = 318; 55% female) consisted of youth aged 14–18 and was predominantly White/non-Hispanic (76.3%). Results supported four
meaningful yet distinguishable profiles of youth purpose that are largely consistent with theories on identity formation:
Achieved, Foreclosed, Uncommitted, and Diffused. Hypothesized linkages with affect and hope were established across the profiles
such that positive emotions and goal-directed thinking were most apparent among Achieved and Foreclosed youth and least apparent
among Diffused and Uncommitted youth. Overall, findings demonstrate the inherent complexity in adolescents’ engagement with
purpose and suggest a correspondence between stronger commitments to purpose and youths’ sense of personal agency and well-being. 相似文献
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Ellen H. O’Donnell Melissa Moreau Esteban V. Cardemil Alisha Pollastri 《Journal of youth and adolescence》2010,39(1):12-22
Research on the mechanisms by which interparental conflict (IPC) affects child depression suggests that both parenting and
children’s conflict appraisals play important roles, but few studies have explored the role of general cognitive style or
included both parenting and cognitions in the same design. Moreover, the effects of IPC on minority children are not well
understood. In this longitudinal study, parenting was examined as a mediator of the relation between increasing IPC and change
in depression. General cognitive style was included as a moderator. The combined influence of parenting and cognitions was
also explored. A racially and ethnically diverse sample of 88 fifth and sixth graders from two urban schools reported their
cognitive style, depressive symptoms, and perceptions of conflict and parenting at two time points separated by one year.
Parental warmth/rejection mediated the relation between IPC and depression, and general cognitive style acted as a moderator.
Parenting, cognitive style, and IPC did not significantly interact to predict change in depression over time. Findings indicate
that both parenting and children’s general cognitive style play a role in understanding the impact of increasing IPC on children’s
well-being. 相似文献
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Tobias Jung Tim Scott Huw T. O. Davies Peter Bower Diane Whalley Rosalind McNally Russell Mannion 《Public administration review》2009,69(6):1087-1096
Organizational culture is widely considered to be one of the most significant factors in reforming and modernizing public administration and service delivery. This article documents the findings of a literature review of existing qualitative and quantitative instruments for the exploration of organizational culture. Seventy instruments are identified, of which 48 could be submitted to psychometric assessment. The majority of these are at a preliminary stage of development. The study's conclusion is that there is no ideal instrument for cultural exploration. The degree to which any measure is seen as "fit for purpose" depends on the particular reason for which it is to be used and the context within which it is to be applied. 相似文献
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My brand new bicycle had been stolen! Disbelief. Anger! Disappointment... I had been riding it for only a day,and was as excited as a,well,a boy with a new bike. Even though I only paid what would be the equivalent of half a tank of gas for my truck back home,I was still sorely put out. 相似文献
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