The influence of hypnotics on the development of morphological and biochemical wound reaction (author's transl)]

The influence of hypnotics (barbital and carbromal) on the development of the early wound reactions in mechanically injured skin of guinea pigs was investigated: 1) The cellular reactions in incised wounds were retarded after moderate intoxication by hypnotics (300 mg/kg barbital; 3 g/kg carbromal). The histomorphological changes in wounds were inhibited by carbromal twice as much as by barbital. The hitherto published investigations had not shown any retardation of the early cellular inflammation by weakening influences such as loss of blood or alcohol without symptoms of shock (Berg et al., 1977) or local disturbances by acids and bases (Kampmann et al., 1978). 2). A moderate delay of the activity of structure bound enzymes was found in barbital intoxication, a stronger restriction under the influence of carbromal. 3) After barbital intoxication significant elevation of histamine or serotonin in wounds was not seen. Under the influence of carbromal there was also no increase of histamine but an increase of serotonin. Thus, although the cellular reactions seem to be the most reliable indicator among the methods for the determinations of wound age under devitalizing influences, their value is reduced in cases of intoxications by hypnotics needing treatment. Possible pathophysiological connections of the alterations of morphological and biochemical wound reaction with shock are discussed.     

An Illicit Love Affair During the Third Reich: Who is My Grandfather?*

More than 60 years after an illicit love affair had occurred between Erika H, wife of a Wehrmacht soldier, and a Polish slave worker during World War II, we could clarify the blood relationships of her daughter Uta. When Erika H had become pregnant both of the men could have fathered the child. Erika H was found guilty of fraternization and imprisoned at Ravensbrück concentration camp. She gave birth to Uta and died there in 1944. Uta survived the war as did Erika's husband Gustav, who accepted Uta as his child. Blood samples from family members were taken and DNA extracted. A panel of 16 short tandem repeat (STR) loci were amplified and separated by capillary electrophoresis and the likelihoods calculated using the MLINK software. The combined genotypes yielded a cumulative likelihood ratio of over 200,000 against paternity of Gustav H. This case serves to illustrate the utility of STR profiles for complex deficiency kinship analysis.     

Paradox of voting under an urn model: The effect of homogeneity

We propose a simple Pólya-variety urn model for calculating paradox-of-voting probabilities. The model contains a homogeneity parameter, and for specific values of this parameter the model reduces to cases previously discussed in the literature. We derive a Dirichlet family of distributions for describing the assignment of preference profiles in large committees, and we show how the homogeneity parameter relates to measures of similarity among voters, suggested in prior studies.     

The European Union and Mutual Assistance: More than Defence

Abstract

The first activation of the European Union’s “Mutual Assistance Clause”, following the 13 November 2015 terrorist attacks in Paris, demonstrated that this article can be used very flexibly, not just to help defend French territory but also its expeditionary operations. But if flexibility is an asset, improvisation is not. In order to maximise the potential of the clause, the role of the EU institutions needs to be clarified, in addition to that of the member states, and new capacities must be created at the EU level, notably in intelligence and planning.     

Five Areas of Value Judgement in Local Adaptation to Climate Change

Abstract

Climate change has generated several new theoretical and policy challenges, many of which concern how local communities ought to adapt to a warmer climate. This paper identifies and analyses a number of value judgements that come to the fore as local authorities adapt to climate change. Five categories of judgements are discussed: evaluation (how should the consequences of adaptation be evaluated?), timing (when should adaptive action be taken?), distribution (how should the benefits and burdens of adaptation be distributed?), procedures (who should be involved in adaptation decision making?), and goal conflicts (how should goal conflicts in adaptation be dealt with?). For each category, further research is needed to assist decision making at the local level.     

Corruption in the Informal Sector: Evidence from West Africa

Using a unique dataset, this paper analyses the causes and impacts of bribery in the informal sector in West Africa. It investigates the determinants of the incidence of bribery and the magnitude of the bribes actually paid. Our results show that the mechanisms at play are no different than those found for the formal sector by other authors. With respect to the impacts of corruption on a firm’s performance, our findings show that experience of corruption increases business performance, but that this effect is driven by just one category of informal firm: constrained gazelles.