Interpretation of a 3,4-methylenedioxymethamphetamine (MDMA) blood level: discussion by means of a distribution study in two fatalities

The amphetamine derivative 3,4-methylenedioxymethamphetamine (MDMA, "Ecstasy" is a currently used or abused designer drug and fatalities are frequently encountered in forensic practice. However, the question remains open whether an MDMA blood level can be toxic or even potentially lethal. In order to provide insight in the interpretation of a detected MDMA concentration, the distribution of MDMA and its metabolite 3,4-methylenedioxyamphetamine (MDA) in various body fluids and tissues was studied and discussed in two different fatalities. Apart from peripheral blood samples (such as femoral and subclavian blood), various blood samples obtained centrally in the human body and several body fluids (such as vitreous humour) were examined. In addition, various tissues such as cardiac muscle, lungs, liver, kidneys, and brain lobes were analysed. In contrast to the peripheral blood levels, high MDMA and MDA levels were found in cardiac blood and the majority of the organs, except for the abdominal adipose tissue. The high concentrations observed in all lung lobes, the liver and stomach contents indicate that post-mortem redistribution of MDMA and MDA into cardiac blood can occur and, as a result, blood sampled centrally in the body should be avoided. Therefore, our data confirm that peripheral blood sampling remains "the golden standard". In addition, a distinct difference in peripheral blood MDMA concentrations in our two overdose cases was established (namely 0.271 and 13.508 microg/ml, respectively). Furthermore, our results suggest that, if a peripheral blood sample is not available and when putrefaction is not too pronounced, vitreous humour and iliopsoas muscle can be valuable specimens for toxicological analysis. Finally, referring to the various mechanisms of death following amphetamine intake, which can result in different survival times (e.g. cardiopulmonary complications versus hyperthermia), the anatomo-pathological findings and the toxicological results should be considered as a whole in arriving at a conclusion.     

An alternative method to screen for pepper spray residue

A method was developed to screen for pepper spray residue using instruments and methods other than those techniques commonly employed to analyze chemical residue (i.e.. gas chromatography mass spectrometry-GCMS or liquid chromatography mass spectrometry-LCMS). The method employed gas chromatography (GC), thin layer chromatography (TLC), and diffuse reflectance infrared Fourier transform spectroscopy (DRIFTS) to screen for dried pepper spray stains. Pepper sprays from nine different manufacturers were investigated. Capsaicin and dihydrocapsaicin were identified and unique IR reflectance spectra are presented. An additional five compounds were presumptively found. Results showed that a particular stain could be characterized as a pepper-based stain.     

Further studies on spot tests and microcrystal tests for identification of cocaine

The presence of cocaine in illicit drug samples is still being determined in some laboratories using spot tests and microcrystal tests. Seventeen chemical species were tested using three different spot tests (Wagner, Marquis, and cobalt thiocyanate followed by stannous chloride reactions) and two microcrystal tests (gold chloride and platinic chloride) to determine whether the results could be differentiated from the results of these tests on cocaine. The data obtained indicated that nine of the 17 compounds gave results similar to those from cocaine using the three spot tests, but that the results from microcrystal testing allowed for differentiation of all nine compounds from cocaine.     

当前大学生恋爱中不良倾向的分析与思考

当前在大学生恋爱中存在的低龄化、休闲化、时尚化、体验化、实用化、“快餐化”和放纵化等不良倾向，对大学生的成长和成才构成了很大威胁。学校必须加强对大学生恋爱的教育、管理和指导。     

Blood droplet dynamics--I

The interpretation of bloodstain patterns at crime scenes has received increased attention in recent years. Important to an understanding of this is knowledge of the fundamentals of blood droplet formation and impact dynamics. A review of the literature reveals that a considerable amount of work has been done with aqueous drop dynamics. Workers in the forensic science area seem to have been unaware of this. In addition, some of the most important and comprehensive early work with blood droplet dynamics seems to have been forgotten. It is not cited in more recent publications dealing with bloodstain pattern interpretation. This literature is reviewed and discussed as well. The present study presents results of experiments with blood droplet dynamics and high-speed photographs of blood droplet impacts on stationary target surfaces. Some longstanding misconceptions of importance to forensic scientists engaged in crime scene reconstruction are discussed.     

Managing Equality in Social Dilemmas: Emotional and Retributive Implications

The equality rule is an important coordination rule in symmetric public good dilemmas. Although prior research emphasized that people use the equality rule out of efficiency concerns (as it helps to obtain the public good in the most efficient manner among group members), it may also reflect a true preference for fairness. More precisely, research examining emotional and retributive reactions as a result of a violation of the equality rule by a fellow group member showed that equality indeed is related to people’s personal values and what they consider to be fair. The present paper suggests that a violation of the equality rule results in emotional reactions, and these emotional experiences encourage further retributive actions. The different reactions following an equality violation are described as a function of three features: (1) the motives to use equality, (2) attributions for explaining the violation, and (3) the honesty of the given explanation. The write-up of this paper was partly supported by GOA/05/04 from the Research Fund of the Katholieke Universiteit Leuven. The research and write-up was supported by a fellowship of the Netherlands Organization for Scientific Research (NWO, Grant No. 016.005.019), awarded to the second author.     

Mediation in Italy: Exploring the Contradictions

This article sets Italy in the context of three primary approaches to promoting mediation use in Europe: cultural, pragmatic, and legalistic. Despite the fact that Italy could be considered a "front-runner" in the latter category, the actual number of cases going to mediation to date has remained low. Drawing on both data from a recent CPR European Committee survey and aspects of the broader Italian legal and social context, this article explores reasons for this apparent contradiction and concludes by suggesting general principles that can be extrapolated from the Italian experience.