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191.
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Alcohol--orally given in concentrations from 1 to 4 g/kg body-weight--leads to a reduction of mast cells in the guinea pig lung. At the same time a minor decrease of histamine concentration was observed. The incompatibility reaction with alcohol after disulfiram intake (DAR) shows an additional degranulation oft mast cells of the lungs and decrease of histamine-content. So far, there seems little difference between the influence of disulfiram alone and the DAR. Besides thrombocytes and basophile leucocytes, the mast cells of the lung are responsible for the release of histamine and serotonine during higher alcohol concentrations and alcohol-disulfiram-reactions. We think that the intolerance phenomena of humans after alcohol--f.e. in form of flush-reaction--is at least partly related to the concomitant influence oft mast cell-substances.  相似文献   
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Book reviews     
A. L. Meiendorf, Optimizatsiya khozyaistvennykh reshenii: metod analiza prirashchenii. Series: Aktual'nye problemy sel'skogo khozyaistva. Moscow: ‘Ekonomika’, 1976.

Oliver H. Radkey, The Unknown Civil War in Soviet Russia. A Study of the Green Movement in the Tambov Region, 1920–21. Stanford, Calif.: Hoover Institution, 1976. xiv+457 pp. $12.95.

Roy and Zhores Medvedev, KhrushchevThe Years in Power. London: OUP, 1977. xi+198 pp. £3.95.

Daniel F. Calhoun, The United Front: the TUC and the Russians, 1923–1928. Cambridge: CUP, 1976. 450 pp. £10.50.

Gabriel Gorodetsky, The Precarious Truce. Anglo‐Soviet Relations 1924–27. Cambridge: CUP, 1977. 289 pp. £9.00.

Herbert S. Dinerstein, The Making of a Missile Crisis: October 1962. Baltimore and London: Johns Hopkins UP, 1976. 302 pp. $14.95.

Donald R. Kelley, Kenneth R. Stunkel, Richard R. Wescott, The Economic Superpowers and the Environment: The United States, The Soviet Union, and Japan. San Francisco: W. H. Freeman & Co., 1976. 335 pp.

Fred Singleton (ed.), Environmental Misuse in the Soviet Union. New York and London: Praeger Publishers, 1976. xvii+103 pp. $13.50. £8.80.

Peter H. Juviler, Revolutionary Law and Order. Politics and Social Change in the USSR. New York: The Free Press, and London: Collier MacMillan, 1976. xii+274 pp. £11.05.

Richard Szawlowski, The System of the International Organizations of the Communist Countries. Leyden: A. W. Sijthoff, 1976. 322 pp.

Jürg Meister, Soviet Warships of the Second World War. London: Macdonald & Jane, 1977. 348 pp. £7.95.  相似文献   

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Book reviews     
David Granick, Enterprise Guidance in Eastern Europe. A Comparison of Four Socialist Economies. Princeton, N.J.: Princeton UP, 1976. xvi+505 pp. £17.20 or £6.10 (paperback).

A. Zauberman, Mathematical Theory in Soviet Planning (Concepts, Methods, Techniques). London: OUP for the Royal Institute of International Affairs, 1976. xiv+464 pp. £17.00.

H. Gordon Skilling, Czechoslovakia's Interrupted Revolution. Princeton, N.J.: Princeton UP, 1976. 924 pp. £31.30 or £10.50 (paperback).

Alex Pravda, Reform and Change in the Czechoslovak Political System: January‐August 1968. Sage Research Papers in the Social Sciences, vol. 3, series No. 90–020 (Contemporary European Studies Series). Beverly Hills and London: Sage Publications, 1976. 96 pp. £1.30.

R. G. Gidadhubli (ed.), Fifty Years of Soviet Power—a Study of Social, Economic and Political Developments. Centre of Soviet Studies, University of Bombay, 1976. 295 pp. 29 rupees.

Occasional Papers, Centre for Soviet and East European Studies, Jawalharlal Nehru University, New Delhi, Nos. 2 and 3, 1976 (mimeographed).

Adam B. Ulam, A History of Soviet Russia. London: Martin Robertson, 1976. viii+312 pp. £5.00.

Olga A. Narkiewicz, The Green Flag: Polish Populist Politics 1867–1970. London: Croom Helm, 1976. 314 pp. £7.95.

Jacques Levesque, L'URSS et la révolution cubaine. Montreal: Presses de 1'Université de Montréal, 1976. 221 pp.

John B. Dunlop, The New Russian Revolutionaries. Belmont, Mass.: Nordland, 1976. 344 pp. $18.50.

Brian Hunter, Soviet‐ Yugoslav relations 1948–1972: a bibliography of Soviet, Western and Yugoslav comment and analysis. New York and London: Garland, 1976. 223 pp. $20.00.  相似文献   

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Abstract. Since the Glassco Commission in the early sixties there has been a plethora of administrative changes: Program Planning and Budgeting, Operational Performance Measurement Systems, Management by Objectives, and Cost/Benefit Analysis have all been introduced as technical panaceas. In terms of processes, some should probably have been changed but remain the same(such as the personnel selection-promotion process), while others have been circumvented (the regular budgetary process). Still others have been changed (the cabinet committee process) but have produced results of questionable value and perhaps positive harm to majority governments. It is contended that the Glassco injunction ‘let the manager manage’ and the assumption that private sector practices should be adopted by government, virtually without modification, ignore fundamental differences between the two sectors. The war between competing interest groups is inevitable and hence perpetual. Governments engage in a rolling set of compromises between factions in an essentially adversarial process under rules, formal and informal, that restrict the field of battle. Frequently, those who advocate administrative changes are in pursuit of their personal interests. They frequently find themselves in alliances with one or more of the contending parties who look upon them as guns for hire to be used or rejected on strategic grounds. After an impressionistic critique of each of the processes and techniques previously cited, the paper ends on a more positive note. There is a plea that the powers of the auditor general be expanded to encompass reporting upon (as distinct from undertaking) the extent to which a ministry is carrying out efficiency and effectiveness studies, where there is a consensus about the validity of the data and methodology. It is also suggested that the auditor general report upon the disposition of these studies with the aim of breaking down present secrecy barriers. A better informed public would change the incentive structure within which ministers, aided by officials, reach their decisions. Sommaire. Depuis la Commission Glasscoe, au début des années 60, il y a eu une pléthore de changements administratifs. La Planification et l'établissement des budgets par programme, les systèmes de mesure des performances opérationnelles, la gestion en function des objectifs, l'analyse des coûts et avantages, tous ces systèmes ont été utilisés comme panacées techniques. Du point de vue des processus, certains, qui auraient dû sans doute être changés ne l'ont pas été (comme par exemple la sélection du personnel et le processus de l'avancement) alors que d'autres ont été contournés (le processus budgétaire normal). D'autres encore ont été changEeAs (le processus des comités de cabinet) mais pour produire des résultats de valeur douteuse et parfois franchement défavorables pour les gouvernements majoritaires. L'auteur soutient que l'impératif de la Commission Glasscoe « laisser gérer les gestionnaires » et le postulat suivant lequel les pratiques du secteur privé devraien être adoptées pratiquement sans modification par les gouvernements ignorent les différences fondamentales qui existent entre les deux secteurs. La lutte entre des groupes aux intérêts divergents est inévitable, et done perpétuelle. Les gouvernements s'engagent dans tout un jeu de compromis dynamiques entre les différentes factions dans ce qui essentiellement un processus antagoniste, à l'intérieur de règies formelles ou non formelles, qui réduisent la portée du conflit. Fréquemment, ceux qui réclament des changements administratifs le font dans leur propre intérêt et ils se trouvent souvent alliés à un ou plusueurs des partis d'opposition qui les considèrent comme des mercenaires à utiliser ou rejeter pour des raisons stratégiques. Après une critique subjective des divers processus et techniques cités précédemment, l'auteur conclut sur une note plus positive. Il demande que les pouvoirs de l'Auditeur général soient étendus pour qu'il fasse connaître (et non pas pour qu'il étudie) la mesure dans laquelle les ministères effectuent des études sur l'efficience et l'efficacité, là où il existe un consensus quant à la validité des données et de la méthodologie. Il propose aussi que l'Auditeur général fasse rapport sur l'usage qui est fait de ces études, afin de supprimer le secret qui l'entoure actuellement. Un public mieux informé transformerait la structure de la motivation qui entoure actuellement les ministres qui prennent des decisions et leurs fonctionnaires.  相似文献   
199.
This article explains political radicalism by the number of voters who are biased towards a party. With little voters biased in favor of a party, this party has to rely more heavily on its programmatic distance to other parties. Because large parties – i.e.: parties with a high number of biased voters – gain votes when they move to the center of the political spectrum, parties with a lower number of voters that are biased in their favor are forced to the edges of the policy space. We draw on a computational model of political competition between four parties in a two‐dimensional policy space to investigate this relationship. We use panel corrected OLS estimates to analyze the data generated by the computer simulation. Our results substantiate the hypothesis of a negative relationship between the number of biased voters and the inclination of a party to adopt a more extreme policy stance.  相似文献   
200.
Most accounts of Swiss federal institutions are unable to explain institutional change. In this contribution the authors trace change in Cantonal reforms and then use multivariate explanation models to account for institutional reforms such as New Public Management reforms. The multivariate analyses used rely on an “event count model” to explain the frequency of institutional reforms and a “binary response model” to explain why Cantons adopt New Public Management reforms. This research demonstrates that policy research as well as innovation and diffusion theories can contribute to explaining institutional reform.  相似文献   
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