The Confidence Game: Roping in a Globalized World

This is the last in a series of five articles focusing on how Bernard Madoff’s confidence game (con game) worked. It examines the international money collecting activities by ropers for Bernard L. Madoff Investment Securities (BLMIS). Before globalization, Madoff’s con game brought him millions of dollars; after globalization, it began bringing him billions, making him remarkably successful until his run of luck was brought to a sudden halt by the worldwide economic downturn.     

The Effects of German Unification on the Federal Chancellor's Decision-Making

The purchase of Germany's Mannesmann AG by Britain's telecommunications holding company Vodafone in spring 2000 represented the first major cross-border hostile takeover in German corporate history. As spectacle, the story surrounding the fall of one of Germany's grandest industrial giants lays bare the underlying themes shaping the country's national discourse over how to build a new national consensus on the function of economic activity for the state, for society, and for the German citizen. As such, the Mannesmann-Vodafone saga contains a clear caesura between the Old and the New Economy in Germany. Of course the question remains which values and institutions do the Germans want to carry over from the old world into the new. And there the line between past and present becomes distinctly less discernible.     

Construction of a roller device for the collection of hair and fiber evidence.

The discovery of hair and fiber evidence can be of critical importance in the investigation of crimes, particularly violent crimes. A procedure is described for the construction and assembly of a roller device that utilizes readily available components and single-sided adhesive tape. The advantages over previously described roller devices include decreases in both the potential for contamination and the time required for construction of the device, as well as the ability to disinfect all of the roller components.     

NEW DIRECTIONS IN MEDICAL OUTCOMES RESEARCH: THE VIEW FROM HARVARD

This study evaluates the emerging field of medical outcomes research based on interviews at Harvard Medical School. Medical outcomes research at Harvard is multifaceted, but may be summarized as involving certain key components. The emphasis at Harvard is on “quality of care,” viewed as a combination of outcomes evaluation and process evaluation, delivery of the service and its result. In a time of shrinking budgets, outcomes and process research can be justified economically because of the relatively low cost of patient self‐reports and because of their usefulness. Physicians may be motivated to measure quality of care by emphasizing the positive effects of research on the process of care and outcomes. Medical outcomes research is a field that is undergoing change and is becoming increasingly oriented toward the practical needs of patients and physicians.     

Managing incidental findings in human subjects research: analysis and recommendations.

No consensus yet exists on how to handle incidental findings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are findings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two-year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed.     

Molecular characterization of a null allele at locus DXS8378

Typing of X-chromosomal short tandem repeat (STR) loci in a deficiency paternity case revealed a single Mendelian incompatibility between a female child and her putative grandmother, consisting of an opposite homozygosity at locus DXS8378. The presence of a null allele due to a primer binding site mutation on the child's paternally inherited X chromosome was confirmed by amplification with newly designed DXS8378 external primers. Sequencing analysis showed a point mutation (C > T transition at position 168, according to GenBank accession G08098) in the binding site of the original DXS8378 reverse primer.