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91.
Campaigns and political parties are faced with the immensely important practical challenge of financing their efforts. Raising money is instrumental to all other aims. In recent years, this task has been complicated by the need to enlist ever greater numbers of contributors to raise ever larger sums of money. At the same time, fundraising burdens are eased a bit because contributors flock together. That is, campaign contributing is a spatially dependent phenomenon, associated with affluence and the presence of networks. Accordingly, geospatial tools provide a helpful method for understanding and predicting where contributions can be most successfully mined. 相似文献
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Oxycodone is a potent semi-synthetic narcotic prescribed for the management of pain. Previous investigators have reported that the abuse of oxycodone is most frequently seen in conjunction with the abuse of other drugs, although fatalities have been reported with oxycodone alone. We undertook a retrospective review of cases investigated by the Palm Beach County Medical Examiner's Office in which postmortem toxicologic studies indicated the presence of oxycodone. A total of 172 consecutive cases were studied, including 18 in which death was attributed to oxycodone toxicity, 117 to combined drug toxicity, 23 to trauma, 9 to natural causes and 5 to another drug or drugs. The postmortem blood concentrations of oxycodone overlapped among the groups. The mean blood oxycodone concentration among the cases of oxycodone toxicity was 0.69 mg/L, combined drug toxicity 0.72 mg/L and trauma 0.62 mg/L. Concentrations were lower in cases of deaths attributed to natural causes and to another drug or drugs (mean each 0.087 mg/L). Benzodiazepines, detected in 96 cases, were the most common co-intoxicants in the cases of combined drug toxicity, followed by cocaine, which was found in 41. The most frequently encountered benzodiazepine was alprazolam. This study confirms that deaths in which oxycodone is a factor are most commonly cases of combined drug toxicity. The high incidence of alprazolam as a co-intoxicant has not been previously recognized. 相似文献
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Lipworth W 《Journal of law and medicine》2005,13(2):245-255
In the "post-genomic" age of biomedical research, researchers often wish to utilise collections of human tissue. This type of research raises many ethical and legal issues and anyone wishing to use such collections is faced with an enormously complex set of regulatory requirements, many of which are still ambiguous, reflecting ongoing ethical and legal debate. Whilst there is no way of entirely avoiding such regulatory complexity and ambiguity, conceptual frameworks can assist those who wish to use, administer, authorise and generate policy on tissue banking research. Two conceptual frameworks are described here: a taxonomy of tissue banking practices, aimed at assisting those who need to ensure that tissue banks meet ethical and legal requirements; and a "syncretic" approach to policy-making, for those who wish to generate new policy, or streamline existing policy relating to tissue banking research. 相似文献
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Terance D. Miethe Timothy C. Hart Wendy C. Regoeczi 《Journal of Quantitative Criminology》2008,24(2):227-241
Derived from comparative approaches in both qualitative and quantitative research, the current study describes a simple exploratory
technique for the multivariate analysis of categorical data. This technique is referred to as the conjunctive analysis of
case configurations. After describing the logic and underlying assumptions of this conjunctive method, it is applied and illustrated
in the study of the federal sentencing of drug offenders. The relative value of this conjunctive approach for purposes of
exploratory data analysis and its overall utility as a method for confirmatory research are also discussed.
相似文献
Terance D. MietheEmail: |
98.
A structural equation model based on social cognitive theory was used to predict relationship violence from young adolescents' knowledge, self-efficacy, attitudes, and alternative conflict strategies (n = 143 male and 147 female grade 7-9 students). A direct causal effect was supported for violence-tolerant attitudes and psychologically aggressive (escalation/blame) strategies on physical violence against dating partners and friends. Knowledge and self-efficacy contributed to using reasoning-based strategies, but this reduced violence only in boys' friendships. Knowledge reduced violence-tolerant attitudes, thus reducing escalation/ blame and physical violence. Attitudes toward male and female dating violence (ATMDV and ATFDV) were indicators of general attitudes toward violence among non-dating students but ATFDV affected physical violence and ATMDV affected psychological aggression for both dating boys and girls. 相似文献
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This practical note outlines Concern's approach to pro-poor budget analysis using the case of the Kenya Free Primary Education (FPE) policy. Analysis conducted on the outcomes of the FPE policy for Nairobi's urban slum-based poor suggests that the policy is not being implemented evenly within the city. The reasons stem from poor allocation and planning approaches, to political interference and unwillingness of teachers to work in slum-based schools. These have the unintended effect of increasing inequities for the urban poor, the reverse of the policy intention. The note outlines the pitfalls and practicalities of conducting this type of analysis. 相似文献
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