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This paper discusses whether the region which in the 1990s has been called the Visegrád Four is a political and/or cultural whole and if so, in what respects. Using the concepts centre and periphery the paper argues that parts of contemporary Central Europe were political and cultural centres of the European civilisation in previous eras. The interpretation and use of this past in the Central European states' contemporary endeavour to join NATO and the EU is discussed. That historical chronology is superseded by what may be labelled the mythological presence of things past is especially noted.  相似文献   
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Policy Sciences - Governments and parliaments struggle to design biomedical policies: while research and practice make rapid progress, they often trigger value conflicts. One response involves...  相似文献   
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Knowledge concerning the distribution of methadone in postmortem human tissue and the effect of postmortem redistribution on methadone is today limited making the choice of a suitable substitute for femoral blood difficult when this is not available. Cardiac blood, femoral blood, muscle, and brain tissue concentrations of the enantiomers of methadone and its metabolite 2‐ethyl‐1,5‐dimethyl‐3,3‐diphenylpyrrolinium were recorded for 155 postmortem cases. Brain and muscle tissue concentrations exceeded the femoral blood concentrations with a median fold of 2.3 and 1.6, respectively, but both had a better correlation than cardiac blood to femoral blood concentrations. The Kruskal–Wallis test showed a significant dependency on time and body mass index for some of the matrix ratios over femoral blood. We conclude brain or muscle tissue may constitute a better alternative for measurement of methadone than cardiac blood for situations in which femoral blood is not available, despite concentrations in both matrices being systematically higher.  相似文献   
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Patients suffering from psychiatric disorders have an excess mortality and a shorter life span expectancy compared to the general population. Furthermore, they are treated with multiple drugs and are known to have an increased risk of drug abuse. In this study, we aimed at investigating the pharmaceutical drug and drug of abuse profiles of the deceased included in the Danish prospective autopsy‐based forensic study on psychiatric patients, SURVIVE. Using the postmortem systematic toxicological analysis results, we identified 129 different consumed compounds in our population (n = 443). Polypharmacy (≥5 compounds) was detected in 39.5% of the deceased. Deceased with a psychiatric diagnosis or who died from a fatal intoxication had significantly more compounds at the time of their death compared to having either no psychiatric diagnosis or another cause of death, respectively. Evidence of drug abuse was present, as 29.8% of our total population had consumed either methadone or illicit drugs of abuse, excluding tetrahydrocannabinol. Of those deceased with a psychiatric diagnosis, 33.6% had either consumed methadone or illicit drugs of abuse, a greater number than those without a psychiatric diagnosis. Fatal intoxication was the most frequent cause of death (40.6%) with methadone as the major intoxicant. Here, we found that those without a psychiatric diagnosis had fewer fatal pharmaceutical drug intoxications compared to the psychiatric diagnosis groups. Our findings add further context to understanding the excess mortality of psychiatric patents, since there is an increased occurrence of fatal intoxication, polypharmacy, and drug abuse in this population.  相似文献   
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This article looks at co-ordination within humanitarian mine action (hma), and co-ordination between hma and other humanitarian and development initiatives. The discussion focuses specifically on the role of UN-led Mine Action Centres (macs) and the analysis draws on case studies of Bosnia and Herzegovina and Afghanistan. A contention throughout is that macs often employ a rigid approach to co-ordination. This constricts the flexibility of mine action organisations, limits the development of creative initiatives and poses a barrier to co-ordination between hma and other humanitarian initiatives. A second point pursued is that co-ordination arrangements are embedded in a broader institutional context, and this context has in turn the potential to impact on co-ordination. The analysis presented here suggests a number of implications for hma in general, together with a number of policy considerations. The article concludes by offering some thoughts for the future on the importance of effective co-ordination arrangements both within hma as a sector and between hma and other sectors of humanitarian assistance.  相似文献   
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Abstract

Drawing on the constructivist concept of ‘securitisation’, this article analyses Russia's perceptions of, and responses to, Norway's Svalbard policy in the 1990s and 2000s. The analysis focuses on three policy issues which have figured prominently on Russia's arctic security agenda in recent years: (1) the establishment and use of civilian radars and satellite ground stations on the archipelago, (2) the adoption of the Svalbard Environmental Protection Act, and (3) the Norwegian Coast Guard's fishery enforcement measures in the Svalbard Fisheries Protection Zone. The article concludes that despite the changes that have taken place in the Euro-Arctic region after the Cold War, Svalbard has not ceased to be a security concern for Russia.  相似文献   
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Why Democracies May Actually Be Less Reliable Allies   总被引:1,自引:0,他引:1  
Recent research builds on the observation that democracies have more durable alliances to argue that democracies make more reliable allies. This need not be the case. Alliances serve as commitment devices, adding ex ante credibility to states' claims about ex post behavior. Variation in alliance durability must reflect differences in the desirability of formalizing alignments. Put simply, democracies are "most improved" by formal commitments. We offer two related explanations for why democracies might actually be less reliable alliance partners. Information costs for participating in policymaking and the advantages of organized interest groups combined with distributional incentives generated by the periodic turnover of governments may conspire to make informal commitments on the part of democracies problematic. Determining the net effect of democratic virtue and vice is best done empirically. We test alliance reliability by focusing on intervention, rather than on the duration or the number of commitments. Our results suggest that democracies make less reliable allies.  相似文献   
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