大鼠液压冲击脑损伤TGF-β1及其受体TβR I的表达

目的观察脑损伤后TGF-β1及其受体TβRI蛋白表达及其时序性变化,探讨脑损伤的分子机制及法医学脑损伤时间推断。方法用免疫组织化学方法观察大鼠液压冲击脑损伤后TGF-β1及其受体TβRI蛋白在伤后不同时间(30 min、1 h、3 h、6 h、12 h、1 d、3 d、7 d)的表达情况,以正常大鼠及手术大鼠作为对照。结果 (1)正常及手术对照组大鼠脑组织内有低水平的TGF-β1及TβRI表达;(2)脑损伤后1～3d,大脑皮质和脑干TGF-β1/TβRI蛋白表达逐渐增加,7 d时仍维持在高表达水平;(3)海马冲击后12 h～1 d逐渐增加,3 d时仍处于高表达水平,7 d时已开始下降。结论脑损伤可诱导TGF-β1/TβRI基因在脑内表达,其时序性改变可望用于法医学脑损伤时间推断。     

广东省交警训练大纲科目设置的原则和内容的层级分布

广东省交警训练大纲科目内容设置首先要遵循三个厚则,一是从实际中来的原则,即不搞凭空设置,必须认真倾听一线交警的意见和建议;二是规范原则,即严格按公安部训练条令和广东省公安机关训练实施办法设置基本科目;三是突出重点原则,即科目中的具体内容安排要做到“四个围绕”,即围绕科技强警,围绕提高交警严格公正文明执法水平,围绕交警业务知识和技能具有实用性和针对性,围绕培养交警具有良好心理素质。其次各种训练科目内容在各层级的分布要做到具有合理性、层次性和螺旋上升性。     

The individuality of fibres used to provide forensic evidence--not all blue polyesters are the same.

Fibres used in forensic casework suffer from a disadvantage common to other forms of trace evidence--it is not possible to state with absolute certainty that they originate from a specific source. Target fibre studies, population studies and research on 'blocks of colour' have effectively demonstrated the polymorphism of textile fibres (particularly man-made ones) and have shown that when a fibre is believed to have a specific putative source, the chance that it has originated from a different source purely by coincidence is extremely remote. A study by Houck MM (Houck MM, Inter-comparison of unrelated fibre evidence. Forensic Science International 2003; 135: 146-149) has shown that no coincidental matching fibres were recovered from items of clothing examined in 20 unrelated crimes. The study involved over two million comparisons. This work goes a step further, and using the example of blue polyester fibres shows that even within a very narrow segment of the whole general fibre population, many examples of a specific colour/type of man-made fibre taken from random sources can be compared and the chance of any two being the same is very low. These studies should help to show the specificity and value of transferred fibres in providing forensic evidence.     

论建立爱国主义教育机制

爱国主义教育机制是对人民群众特别是广大青少年进行广泛、深入、持久的爱国主义教育所建立的组织机构、工作制度和运行方式.只有建立爱国主义教育的长效机制,才能深入持久地搞好爱国主义教育,使爱国主义的优良传统发扬光大.     

宁波市文化产业发展研究

进入21世纪,文化的价值日益凸现,社会对文化消费的需求与日俱增.发展文化产业,繁荣文化事业,满足人民群众日益增长的精神文化需求,已是我市经济社会发展的迫切要求.本文剖析了宁波文化产业发展的现状与问题,分析了发展宁波文化产业的主要优势,提出了发展宁波文化产业的政策建议.     

Doctors in Extremity

Book Reviews in This Article:
Robert Jay Lifton, The Nazi Doctors: Medical Killing and the Psychology of Genocide.
Eric Stovcr and Elena O. Nightingak, eds., The Breaking of Bodies and Minds: Torture, Psychiatric Abuse and the Health Professions.
Elliot S. Valenstein, Great and Desperate Cures: The Rise and Decline of Psychosurgery and Other Related Treatments for Mental Illness.