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601.
Tracy-Lynn E. Lockwood B.S. Tammy X. Leong B.S. Sarah L. Bliese B.S. Alec Helmke B.A. Alex Richard Getahun Merga Ph.D. John Rorabeck M.S. Marya Lieberman Ph.D. 《Journal of forensic sciences》2020,65(4):1289-1297
As drug overdose deaths across the United States continue to rise, there is increasing interest in field testing of illicit substances. This work discusses a paper-based analytical device (idPAD) that can run a library of 12 colorimetric tests at the same time, each detecting different chemical functional groups and materials found in illicit drugs, distractor substances, and cutting agents. The idPAD requires no electricity, costs less than $2 USD, and requires minimal training to operate. The results of the 12 tests form a color barcode which is “read” by comparison to standard images. The accuracy of the idPAD was assessed using samples of heroin, cocaine HCl, crack, and methamphetamine at concentrations of 25%–100% in a lactose matrix, as well as pure lactose. Based on 840 “reads” by three different users, the idPAD showed 95% sensitivity and 100% specificity for detecting these drugs; the most common error was mistaking cocaine HCl for crack or crack for cocaine HCl. In a second step, samples of heroin, cocaine, and methamphetamine (n = 30) and distractor substances (pharmaceuticals, cutting agents, and other illicit drugs, n = 64) were tested by two readers, yielding a sensitivity of 100% and specificity of 97%. Targeted substances were detected reliably at 55–180 μg/lane, and the idPAD was found to be stable for at least 3 months when stored at room temperature. The library approach used in the idPAD may provide the accuracy and robustness necessary for a presumptive field drug test. 相似文献
602.
立足于真实的社会生活实践而不是想象的概念语词,能更好地厘清涉枪案件刑事司法面临的困境。经由枪支认定标准,刑事司法权力突兀地介入普通民众的正常社会生活,打破司法权力与公民权利的基本边际均衡,造成了刑事司法裁量的尴尬。刑法意义上的具有高度危险性的枪支,不应该与普通民众生产、经营、游艺所使用玩具枪、仿真枪的正常活动发生关联。刑事司法不侵扰普通民众的日常生活,这是刑事司法权力与公民社会利益的基本边际均衡。以一个侵扰公民正常社会生活的枪支认定标准为基础对涉枪案件进行“综合考量”,只会增加刑事司法的内部复杂性,进而造成刑事司法正当性的严重削弱。只有直面真实的社会生活实践,摒弃迷恋语词的法律形式主义思维,看重刑事司法的系统性后果,确定适宜的枪支认定标准,维护刑事司法裁量的基本边际均衡,才能有效化解涉枪犯罪司法治理的困境。 相似文献
603.
604.
Cady Berkel Velma McBride Murry Tera R. Hurt Yi-fu Chen Gene H. Brody Ronald L. Simons Carolyn Cutrona Frederick X. Gibbons 《Journal of youth and adolescence》2009,38(2):175-188
Prior research demonstrates negative consequences of racism, however, little is known about community, parenting, and intrapersonal
mechanisms that protect youth. Using a mixed-methods approach, this study illuminated linkages between positive and negative
contextual influences on rural African American adolescent outcomes. Quantitative results provide support for Structural Ecosystems
Theory, in that the influence of discrimination and collective socialization on adolescent outcomes was mediated by racial
socialization and positive parenting. Parenting and community influences contributed to adolescent racial identity and self
image, which protected against common negative responses to racism; including academic underachievement, succumbing to peer
pressure, and aggressive tendencies. Qualitative results indicate that current measures of discrimination may underestimate
adolescents’ experiences. Adolescents reported racist experiences in the domains of school, peers, and with the police (males
only). Moreover, qualitative findings echoed and expanded quantitative results with respect to the importance of the protective
nature of parents and communities.
相似文献
Cady BerkelEmail: |
605.
陈龙,原名刘汉兴,1910年12月出生于辽宁抚顺。他早年参加东北军,“九·一八事变”后,毅然率全连士兵投奔中共党员李延禄率领的抗日救国军(后称抗日自卫军),先后任营长、团长和自卫军副参谋长。 相似文献
606.
与传统民法理论相比,我国代位权行使范围及效果归属作出了变通规定。本文通过对两种理论的比较研究,认为我国的变通规定与代位权制度的设立目的、逻辑体系甚至法律的公平正义精神均有不符。因此,在将来制定民法典时,应采纳传统民法的代位权制度。 相似文献
607.
我国“大部门体制”的理论内涵和改革路径 总被引:1,自引:0,他引:1
建立职能整合、机构协调的大部门体制是我国行政管理体制改革的必然要求。我国的大部门体制是在借鉴西方成功经验的基础上,各项改革不断深化的结果,它围绕政府职能的整合与重组,贯穿决策权、执行权和监督权的分立协调,有利于政府流程再造和现阶段诸多问题的解决。由于国情不同,大部制在我国的顺利推进需要选择与西方截然不同的改革路径。 相似文献
608.
Alex J. Krotulski M.S.F.S. Amanda L.A. Mohr M.S.F.S. Sherri L. Kacinko Ph.D. Melissa F. Fogarty M.S.F.S. Sarah A. Shuda M.S.F.S. Francis X. Diamond B.S. William A. Kinney Ph.D. M.J. Menendez J.D. Barry K. Logan Ph.D. 《Journal of forensic sciences》2019,64(5):1451-1461
This is the first report regarding the characterization of the new synthetic cannabinoid 4F‐MDMB‐BINACA. 4F‐MDMB‐BINACA was first analytically confirmed in seized drug material using gas chromatography–mass spectrometry (GC‐MS), liquid chromatography–quadrupole time‐of‐flight mass spectrometry (LC‐QTOF), and nuclear magnetic resonance (NMR) spectroscopy. Subsequent to this characterization, 4F‐MDMB‐BINACA was detected in biological specimens collected as part of forensically relevant casework, including medicolegal death investigations and drug impaired driving investigations, from a variety of regions in the United States. Further analysis of biological specimens resulted in the identification of the metabolites 4F‐MDMB‐BINACA 3,3‐dimethylbutanoic acid and 4‐OH‐MDMB‐BINACA. 4F‐MDMB‐BINACA is appearing with increasing frequency as a contributory factor in deaths, creating morbidity and mortality risks for drug users. Laboratories must be aware of its presence and impact, incorporating 4F‐MDMB‐BINACA into workflows for detection and confirmation. 相似文献
609.
改革开放三十年来,随着我国经济体制改革逐步深入,企业工资收入分配制度改革不断推进,建立了按劳分配为主体、多种分配方式并存的分配制度, 相似文献
610.
David Farabee Sheldon X. Zhang Benjamin Wright 《Journal of Experimental Criminology》2012,8(3):241-253