青壮年猝死综合征SCN2B、SCN4B基因检测

目的寻找SCN2B、SCN4B基因的变异位点,探讨其与青壮年不明原因夜间睡眠中猝死(SMDS)的关系。方法提取SMDS病例组及健康对照组的基因组DNA,采用聚合酶链式反应(PCR)方法扩增SCN2B、SCN4B基因编码区外显子、外显子-内含子交界区以及3'侧翼区序列,直接行DNA测序以明确遗传变异类型。结果在病例组中共检测到4个变异位点,c.237+27AG,c.*38CT,c.174CT(p.C58C)和c.*7CT。结论本研究首次对中国人SMDS病例进行了SCN2B、SCN4B基因的检测,上述基因是否为中国人SMDS的易感基因尚有待进一步研究证实。     

马来西亚中小企业的发展路径与政策调整——一个制度变迁的分析

发展中小企业是金融危机后马来西亚经济政策的一个显著的调整.本文从马来西亚中小企业发展路径人手,分析了造成马国二元性产业组织结构的制度因素.结合制度变迁理论,文章探讨了马国政府在调整中小企业政策过程中所面临的组织成本、预期收益与有效的制度设计思路,并指出由于制度变迁的路径依赖性,马来西亚中小企业的发展将会是一个渐进的过程.     

中小企业战略转型风险免疫机理研究

本文以一家中小企业为研究对象,基于其战略转型风险因素的识别结果,从组织免疫的视角出发,深入剖析了其系统免疫、功能免疫和辅助免疫对其战略转型风险的应对机理,并尝试构建出中小企业战略转型风险免疫机理的理论模型。     

“发展陷阱”的形成原因分析——兼论中国经济落入发展陷阱的必然性

陷入“发展陷阱”之前的追赶型国家,往往会出现以美元计量的人均名义GDP增长率快于以本币计量的人均实际GDP增长率,这实际上也就是国际相对成本的上升和国际相对竞争力的下降,国内外市场因此会不断被更低收入国家蚕食;人均美元收入的快速提高产生的对生活品质的追求,会导致大量有效需求向发达国家转移。这些表现在企业收支上,也就是成本的提高与收入的减少;在国家层面则表现为外贸收支逆差增加和外汇储备减少或外债增加,由此落入“发展陷阱”。我国目前可能正处在该陷阱的入口。     

Assessing the Effectiveness of NICHD Protocol Training Focused on Episodic Memory Training and Rapport-Building: a Study of Korean Police Officers

The present study examined the effectiveness of 2-day training programs utilizing the NICHD Protocol, with a particular focus on the episodic memory training and rapport-building phases. Ninety-seven police officers were allocated to one of four training conditions (protocol only, protocol and rapport-building, protocol and memory training, protocol and other interview issues), and mock interviews were conducted both before and after the training. The results showed that the proportions of invitations and directive questions asked significantly increased after training, whereas the proportions of option-posing and suggestive questions decreased. Although the different training programs changed interviewing behavior similarly, college students interviewed by police officers who had additional training in rapport-building and episodic memory training were more satisfied with their interviewers than those who were interviewed by police officers in the other conditions.     

分配正义与城乡基本公共服务均等化——基于同一性正义与差异性正义的分析

罗尔斯将平等的自由原则以及机会的公正平等原则和差别原则的结合作为实现正义的两个原则。我们根据人的同一性和差异性,将正义原则概括为同一性原则和差异性原则,认为正义是基于同一性正义和差异性正义相协同的协同正义。并以此运用于分配领域,分析和解决城乡基本公共服务均等化问题,认为同一性正义是其价值旨归,差异性正义是其必要限制和有益补充。     

The application of mitochondrial DNA cytochrome oxidase II gene for the identification of forensically important blowflies in Western China

Blowflies found on human corpses are important for the estimation of the postmortem interval and other questions of forensic relevance. Some of these species are difficult to differentiate morphologically, and therefore a molecular method was elaborated for species identification. Here, we describe a molecular method for rapid identification of these insects. Specific insect DNA fragments were amplified using the polymerase chain reaction, followed by direct DNA sequencing of the amplification products. Analysis of the cytochrome oxidase II sequences revealed abundant phylogenetically informative nucleotide substitutions that could identify blowfly species to species group. In contrast, because of the low level of sequence divergence of sister species, the data could not distinguish among taxa from the same species group, ie, the species within the Lucilia sericata and Lucilia cuprina groups. The molecular data support the existing species group separation of the taxa within the Calliphora. Because of the speed and accuracy of current nucleotide sequencing technology and the abundant apomorphic substitutions available from mtDNA sequences, this approach enables quick identification of species used for estimation of postmortem interval.     

应用Demirjian法进行法医学年龄推断的评价

目的对应用Demirjian法进行法医学年龄推断的准确度及可靠性进行初步评价。方法应用Demirjian法测定828名上海地区青少年(男279名,女549名,11～19周岁)的牙龄,比较所测牙龄和实际年龄的差异。结果在11～14岁年龄段Demirjian法测定的牙龄比实际年龄高估,在15～16岁年龄段低估,在17岁及17岁以上年龄段具有局限性。结论Demirjian法可以用于测定上海地区11～16岁年龄段青少年的牙龄,使用时需进行适当的修正。     

脑血管造影在法医学尸体检验中的应用

脑血管造影作为诊断脑血管疾病的"金标准",目前已经广泛地应用于临床医疗活动中,并积累了丰富的理论和实践资料,是趋于成熟的技术方法。由于因脑血管疾病引发的法医学鉴定案件较为多见,故该技术近年开始应用于法医学,显示出在法医学实践中独特而重要的应用价值。本文对脑血管造影术在法医学中的应用价值进行综述,内容包括辅助定位血管病变或损伤部位、明确出血性质、指导尸体解剖与脑组织病理取材等,并在此基础上展望了该技术在法医学中的应用前景。