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Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in Koreans 总被引:3,自引:0,他引:3
A number of DNA marker types suitable for human identification and parentage testing have been developed, of which single nucleotide polymorphisms (SNPs) merit attention as they are abundant, genetically stable, and amenable to high-throughput automated analysis. In this regard, 24 highly informative SNP markers representing each 22 autosome and both sex chromosomes were selected, and the allele and genotype frequencies of these SNPs were determined in a group composed of 30 unrelated Koreans. Based on frequency data from this group, the estimated probability of identity (P(I)) and probability of paternity exclusion (P(E)) with 22 autosomal SNP loci were 1.905x10(-10) and 98.9%, respectively. The SNPs in this study offer a small but highly accurate database that will be an essential reference for SNP-based forensic application in the future. 相似文献
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This case-control study investigates the relationship between suicide and wealth in Kansas City, Missouri. House and personal property appraisal data on all victims of suicide from 1998 and 2002 and victims from a control population of deaths reported to the Jackson County Medical Examiner during the same time interval were obtained from the Jackson County Government website. The controls were matched to suicide cases by race, gender, year of death, and age at death (+/- 1 year). Data from the 426 members of each group of suicides and controls indicate that suicide victims were: 1) 77% more likely than controls to have lived in houses rather than in apartments or trailers, 2) more likely than controls to have lived in more expensive houses (mean values dollar 70,143 versus dolllar 61,513 respectively, p = 0.04) and 3) more likely to have killed themselves because of factors other than financial strain (8.0% of suicides showed financial strain). 相似文献
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This account of a famous Ashanti festival was written by anEwe scholar, who revisited his native country in 1949, after20 years in Europe. In this time he had a varied career, whichinvolved co-operation in anthropological work, the friendshipof certain well-known Swedish and German physicists, a certainpart in the social and intellectual life of Dublin, in whichhe joined from his Lomeshie Research Centre in Londonderry.He wrote a brief history of West African Art, and proposed inquiriesinto indigenous herbal remedies, and various endemic diseases.He has now returned to Kumasi, to set up a new Research Centre. 相似文献
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European Journal of Law and Economics - Should procedural barriers to constitutional amendment be more onerous than those to the policy changes of ordinary politics? – i.e., should... 相似文献
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