Study of the high polymorphism STR locus-FGA in Chinese population

Population genetic study of the complicated STR locus-FGA was performed by the method of PCR in Han population samples. A total of 21 different alleles including 7 interalleles and 63 different genotypes were observed in 349 unrelated individuals. The observed genotype discrimination showed no significant deviation from Hardy-Weinberg equilibrium and 51 family studies showed no mutation. According to the results obtained in this study(DP = 0.9612, PE = 0.7007, PIC = 0.8333), this system can be used as an useful means in forensic identification of both criminal and paternity case.     

Population study of the CSF1PO,TPOX and TH01 STR polymorphisms in east China

Allele and genotype frequencies of four short tandem repeat loci were determined in a population sample from east China by using PCR and fluorescence techniques. After denaturing PAGE, 9 alleles were identified for CSF1PO, 8 alleles for TPOX, and 7 alleles for TH01. All loci met Hardy-Weinberg expectations. In addition, the theoretical values of these loci for paternity and forensic casework were evaluated.     

武汉地区汉族人群CSF1PO座位多态性分析

应用Ｙｏｓｈｉｄａ设计的ＣＳＦ１ＰＯ新引物对武汉地区３１２例汉族个体作了分型调查,获得了武汉地区汉族人ＣＳＦ１ＰＯ座位的基因频率资料。与Ｈａｍｍｏｎｄ等提出的传统引物扩增效果相比较,本文所选用的引物更适用于法医检案,尤其对严重降解ＤＮＡ材料的分型效果有明显的优越性     

尿样中海洛因代谢物的测定及海洛因滥用的确认

用ＳＰＥ－ＧＣ－ＮＰＤ法建立了尿样中吗啡、６－单乙酰吗啡及可待因的定性分析方法,适用于海洛因滥用者的尿样分析。尿样中吗啡及可待因的最小检测限均为５０ｎｇ／ｍｌ。方法的相对标准偏差分别为：吗啡１１．３％（ｎ＝５）,可待因１４．２％（ｎ＝５）。方法简便、灵敏、快速,１５ｍｉｎ可完成一例尿样的分析。研究了服用含可待因成分的复方甘草合剂后,尿样中的吗啡及可待因的峰面积比为０．４５７±０．１９７（Ｐ＝９９％）;统计了４０例明确滥用海洛因尿液的分析结果,吗啡与可待因的峰面积比为３．４６±０．８９４,Ｐ＝９９％。可作为判断海洛因滥用的依据。同时与免疫板法比较,附５５例免疫板法阳性尿样的分析结果     

Adolescents' Commitment to Developing Talent: The Role of Peers in Continuing Motivation for Sports and the Arts

The role of peer relationships in supporting or hindering adolescents' talent development has received little research attention, despite the importance of peers in adolescents' lives. We conducted semi-structured in-depth interviews with 41 adolescents talented in sports or the arts, and their parents, to investigate (a) the role of peer relationships in adolescents' continued involvement in their talent activities, (b) possible differences in this role by activity domain, and (c) possible gender differences. Thematic analysis indicated that peers typically played a positive function in supporting the continued involvement of talented adolescents in their talent activities. There were differences in opportunities for peer relationships and social satisfaction between in-school and out-of school activities, but not between activity domains. Both males and females mentioned equally social benefits of such involvement. However, females mentioned receiving negative peer attention more frequently than males, and more often cited social dissatisfaction as a significant contributor to decreased involvement or quitting.     

关于加强公安民警艾滋病预防能力的几点思考

公安机关的工作性质 ,决定了许多民警在社会管理工作中和其他警务活动中 ,不可避免地与HIV携带者直接接触 ,极有可能受到感染。就当前对公安民警艾滋病防范知识和能力低下的原因分析 ,提出相应的途径和方法 :1 在公安院校开展预防艾滋病知识教育 ;2 在公安基层开展预防艾滋病知识教育。     

Antecedents of adolescent initiation into stages of drug use: A developmental analysis

The social psychological antecedents of entry into three sequential stages of adolescent drug use, hard liquor, marihuana, and other illicit drugs, are examined in a cohort of high school students in which the population at risk for initiation into each stage could be clearly specified. The analyses are based on a two-wave panel sample of New York State public secondary students and subsamples of matched adolescent-parent and adolescent-best schoolfriend dyads. Each of four clusters of predictor variables, parental influences, peer influences, adolescent involvement in various behaviors, and adolescent beliefs and values, and single predictors within each cluster assume differential importance for each stage of drug behavior. Prior involvement in a variety of activities, such as minor delinquency and use of cigarettes, beer, and wine are most important for hard liquor use. Adolescents' beliefs and values favorable to the use of marihuana and association with marihuana-using peers are the strongest predictors of initiation into marihuana. Poor relations with parents, feelings of depression, and exposure to drug-using peers are most important for initiation into illicit drugs other than marihuana.This research is supported by Grant DA-00064 from the National Institute on Drug Abuse and by the Center for Socio-Cultural Research on Drug Use of Columbia University.Revised version of a paper presented at the Conference on Strategies of Longitudinal Research on Drug Use, San Juan, Puerto Rico, April 1976. Authors' names are listed alphabetically.Received Ph.D. in sociology from Columbia University in 1960. Current research interests are adolescent socialization, longitudinal approaches to the study of human behavior and psychopathology, and processes of interpersonal influence.Received Ph.D. in sociology from New York University in 1975. Major interest is quantitative sociology.Received Ph.D. in sociology from Columbia University in 1975. Current research interests include adolescent socialization and deviant behavior.     

Genetic variation and relationships at five STR loci in five distinct ethnic groups in China

Five short tandem repeat (STR) systems of TH01, vWA, LPL, F13B and FES/FPS were investigated in five ethnic groups living in China (Tujia, Miao, Bai, Chaoxian and Han). All five loci did not deviate from the Hardy-Weinberg equilibrium (P>0.05). At the five loci of each ethnic group, the observed heterozygosity, the mean exclusion chance (MEC), and the power of discrimination (PD) ranged from 0.42 to 0.86, from 0.20 to 0.66 and from 0.61 to 0.95, respectively. For the five ethnic groups, the combined MEC and combined PD were >0. 9360 and >0.9998, respectively, suggesting that combinations of these five systems are feasible for DNA typing in forensic investigations such as personal identification or paternity testing. Furthermore, the allelic frequencies at the five loci suggested that these five ethnic groups were distinctly different communities. Judging from the phylogenetic tree constructed based on the genetic distance among the five ethnic groups, Han, Chaoxian and Tujia were involved in an identical cluster, and Miao and Bai in another. These findings indicate that each of the five groups examined is not only a distinct community, but also has a relationship with each of the others.     

European Union enlargement: Power distribution implications of the new institutional arrangements

Abstract. It is argued that enlargement challenges institutional balances and in particular relative powers of national actors within the European Union (EU). This article concentrates on the impact of future enlargement (with the current negotiating 12 candidates) on power distribution in the Council of Ministers of the European Union and the European Parliament based on the decisions taken at the Nice Summit in December 1800. It uses the Shapley-Shubik and Banzhaf indices to evaluate past and emerging power distributions in both the Council and in the Parliament. A brief section on Turkey (the thirteenth, non-negotiating, official candidate) is included to evaluate its possible impact in the case of admission to the Union.