Field-portable detection of fentanyl and its analogs: A review

The need to detect fentanyl and its analogs in the field is an important capability to help prevent unintentional exposure or overdose on these substances, which may result in death. Many portable methods historically used in the field by first responders and other field users to detect and identify other chemical substances, such as hazardous materials, have been applied to the detection and identification of these synthetic opioids. This paper describes field portable spectroscopic methods used for the detection and identification of fentanyl and its analogs. The methods described are automated colorimetric tests including lateral flow assays; vibrational spectroscopy (mid-infrared and Raman); gas chromatography–mass spectrometry; ion mobility spectrometry, and high-pressure mass spectrometry. In each case the background and key details of these technologies are outlined, followed by a discussion of the application of the technology in the field. Attention is paid to the analysis of complex mixtures and limits of detection, including the required spectral databases and algorithms used to interrogate these types of samples. There is also an emphasis on providing actionable information to the (likely) non-scientist operators of these instruments in the field.     

Informing Policy-Making at Sub-Local Authority Spatial Levels: Using Small Area Micro-Data from the 2001 Census

This article discusses how the release of small area microdata (SAM) from the 2001 UK Population Census could help provide better information in the policy-making process at sub-local authority spatial levels. An experimental set of SAM from the 1991 Census, provided by National Statistics, was used to develop a methodology which can provide SAM estimates of the effects of area at ward level, and can separate these spatial effects from compositional influences due to characteristics of the local area population. These SAM-based results appear to be at variance with census tabular data. It is concluded that 2001 Census SAM could provide an important further source of information for improved policy and target setting at the local area level.     

Distinctly Neoliberal: A Latent Profile Analysis of Neoliberal Ideology and Its Associations with Sociopolitical Actions and Sexual Attitudes

Social Justice Research - Scholars warn that neoliberalism erodes investment in the well-being of others by prizing the self-interested individual. To empirically investigate this claim, we...     

Resisting Broken Windows

Political Behavior - Concurrent housing and opioid crises have increased exposure to street-crime, homelessness and addiction in American cities. What are the political consequences of this...