甘青虎耳草黄酮对H22肝癌小鼠抗肿瘤作用的研究

为探究甘青虎耳草黄酮抑制小鼠H22肝癌原位移植瘤的作用。给小鼠肝接种H22细胞建立肝癌原位移植瘤模型,并随机分组:模型组、环磷酰胺组、甘青虎耳草黄酮剂量组(低、中、高剂量组)和对照组。治疗期间,观察各组小鼠生命体征和生存时间;停药次日,测定抑瘤率、小鼠血清谷丙转氨酶(ALT)、天门冬氨酸氨基转移酶(AST)、血清白蛋白(ALB)、白蛋白/球蛋白比值(A/G)、碱性磷酸酶(ALP)、γ-谷氨酰转移酶(GGT)和岩藻糖苷酶(AFU)水平以及肝组织超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性和丙二醛(MDA)含量。结果显示,各剂量组ALT和AST低于模型组(P<0.05),ALB及A/G比值高于模型组(P<0.05),剂量组ALP、GGT、AFU活性明显低于模型组(P<0.05),其中,甘青虎耳草黄酮各剂量组MDA含量显著低于模型组(P<0.05),SOD、GSH-Px活性显著高于模型组。上述结果表明,甘青虎耳草黄酮能够显著抑制原位移植瘤生长,具有显著抑制肝癌的作用。     

新中国成立初期毛泽东防范化解重大风险的基本战略及其启示

防范化解重大风险的战略策略,是毛泽东安全观的核心内容,也是毛泽东思想的重要组成部分。新中国成立初期,面临着国内反动势力的破坏与反扑,面临西方国家的威胁,面临社会主义革命和建设的艰险。毛泽东深刻洞察各种重大风险,以高屋建瓴、未雨绸缪的战略策略,采取坚决的应对措施和政策。毛泽东和党中央坚持人民民主专政、团结人民,以维护和改善国家安全环境、保卫和巩固新生政权;抗美援朝、坚决反对美国分裂台湾,以维护国家独立、维护国家主权和领土完整;开展社会主义革命和建设,加强国家安全观,维护政治和社会安全。新中国成立初期毛泽东防范化解重大风险的战略,巩固了社会主义政权,维护了社会主义制度,其宝贵经验与实践,对新时代防范化解重大风险有重要的借鉴价值。     

新冠疫情防控常态化下加强创新集体协商工作的思考

由于国外新冠肺炎疫情的快速蔓延以及国内疫情的起伏,使得我国新冠疫情防控呈现出常态化和长期化的趋势。后疫情时期,构建和谐的企业劳动关系,助力企业复工复产和健康发展是工会组织的当务之急。集体协商制度是市场经济国家构建和谐企业劳动关系的根本制度和主要手段,工会组织要积极引导劳动关系双方在集体协商制度框架下主张各自的权利和寻求平衡点。     

Rechtliche Einordnung von Grünbrücken bei Aus- und Neubauten sowie bestehenden Bundesfernstraßen

Natur und Recht - Angesichts der enormen Zerschneidungswirkung von Bundesfernstraßen werden Grünbrücken in der Bundesrepublik vermehrt errichtet, sodass sich die Frage der...     

改制企业与劳动者的确认劳动关系纠纷属民事诉讼受案范围——以谭艮生诉明达公司、石柱县制鞋厂确认劳动关系纠纷案为例

确认劳动关系纠纷是平等主体之间的民事争议,具有民事可诉性,属于人民法院民事诉讼的受案范围。无论是政府及其所属主管部门主导的企业改制还是企业自主改制,均不改变发生在改制企业与劳动者之间的确认劳动关系纠纷的民事争议属性,也不改变其民事可诉性。因此,发生在改制企业与劳动者之间的确认劳动关系纠纷,亦应属于人民法院民事诉讼的受案范围。     

Discrimination of phenethylamine regioisomers and structural analogues by Raman spectroscopy

In this study, the Raman spectra of 21 phenethylamines were obtained using far‐red excitation (785 nm). The distinguishing ability of Raman for phenethylamines, especially for phenethylamine regioisomers and structural analogues, was investigated. Here, the evaluation of a cross section of Raman spectra demonstrated that all types of phenethylamines were distinguishable, even for certain structural analogues with high spectrum similarity. Raman exhibited high distinguishing ability for phenethylamine regioisomers that differ in the substitution position of halogen, methoxy, alkyl, or other substituted groups; as well as for structural analogues containing different groups, such as furanyl, 2,3‐dihydrofuranyl, halogen, and alkyl substituted at the same position. The Raman spectra for homologues with differences in only a methyl group were found to be highly similar; however, their spectra demonstrated small but detectable differences. Four analogue mixtures and 59 seized samples were also analyzed to study the practical use of the Raman method in forensic field. 95% of the seized samples were correctly identified, which significantly validated the ability of Raman method in identifying the correct isomers. Accordingly, this study provides a non‐destructive, high‐throughput and minimal sample preparation technique for the discrimination of phenethylamines.     

Fiscal slack or environmental pressures: which matters more for technological innovation assimilation? A configurational approach

Abstract

Prior studies suggest that fiscal slack may positively affect technological innovation in the public sector but yield inconsistency between theoretical expectations and empirical findings. To address this research gap, this study develops a configurational explanation combining fiscal slack and environmental pressures by employing fs-QCA in the context of Chinese provincial governments’ online public service provision. The findings reveal that the role of fiscal slack is environmentally dependent on explaining technological innovation and that environmental pressures seem to be more important. That is, fiscal slack is likely irrelevant to a high degree of technological innovation assimilation, while the demanding environments of multiple environmental pressures matter. Relative fiscal scarcity may be somewhat relevant to a low degree of technological innovation assimilation only when combined with a more relaxed environment. Several theoretical and practical implications are discussed.     

Laying Bricks For the Future

After breakfast, Li Tianchao, a 6-year-old boy, and his older sister will walk a few hundred meters to Xiaoxian Primary School, where he attends the affiliated kindergarten. Along the way, he will meet his classmates popping out from the old wooden houses scattered along the mountain road.