山茱萸提取物对3T3-L1脂肪细胞葡萄糖消耗与脂肪分解的影响

目的观察山茱萸环烯醚萜苷类提取物对3T3-L1成熟脂肪细胞葡萄糖消耗及异丙肾上腺素(ISO)诱导脂肪分解的影响,探讨其分子机制。方法葡萄糖氧化酶法测定0.04、0.2、1g/L浓度山茱萸提取物干预24h后对脂肪细胞葡萄糖消耗量的影响;比色法测定干预2d后ISO 30min诱导脂肪细胞脂肪分解的甘油释放量;Real-time PCR法检测干预2d后脂肪细胞AMPK、GLUT4和HSL mRNA表达水平,Western blot检测药物对AMPK、ACC蛋白磷酸化的影响。结果 1g/L山茱萸提取物干预成熟脂肪细胞24h后可增加葡萄糖消耗,干预2d后可明显抑制不同浓度ISO诱导的脂肪分解,0.2、0.04g/L提取物可抑制低浓度ISO诱导的脂肪分解;各浓度提取物干预2d可不同程度上调AMPK、GLUT4mRNA水平,下调HSL mRNA表达,1g/L浓度时AMPK、ACC磷酸化水平升高。结论山茱萸提取物可能通过上调AMPK基因表达的相关途径增加3T3-L1脂肪细胞葡萄糖消耗并抑制ISO诱导的脂肪分解。     

盘点2014:中国外交丰收之年(英文)

<正>On 24 December 2014,Foreign Minister Wang Yi attended the opening ceremony of the Symposium on the International Development and China’s Diplomacy in 2014 co-hosted by China Institute of International Studies and China Foundation for International Studies and delivered an address titled 2014 in Review:A Successful Year for China’s Diplomacy.The following is the full text of the address:     

论洗钱犯罪主要途径及侦查措施

当今世界金融一体化和经济全球化方兴未艾,洗钱犯罪的猖獗发展使得社会财富和国民经济遭到严重损失.洗钱犯罪主要途径包括:利用金融机构、地下钱庄、计算机网络、贸易经营、投资实业以及市场交易洗钱等方式.对此,公安机关可采取公开和秘密两种侦查手段.     

从产业链角度分析网络文学版权保护问题

随着网络文学产业的飞速发展,网络文学侵权盗版现象日渐猖獗.面对网络文学产业的困境,本文从产业链角度出发,分析网络文学在全媒体产业链上、中、下游所面临的不同版权保护问题,提出相应的解决策略,从而促进网络文学产业链的良性循环.     

台湾地区民法错误论评析及其借鉴——一个基于法律史和学术史的考察

电商标价错误案引发两岸民法学界对传统意思表示错误制度之共同关注.台湾地区民法错误论源自罗马法一德国法传统,并受到日本法的一定影响.在错误类型上,台湾地区民法沿袭德国“内容错误”与“表示行为错误”之界分,性质错误“视为”内容错误.在错误撤销上,创造性地增加了表意人过失要件之限制,相对人之可归责性亦成为影响表意人行使撤销权之考量要素.两岸民法错误论存在着内生机理上的共通,使得大陆民法错误论寻求台湾地区经验之借鉴成为可能.     

Portable high‐resolution automated 3D imaging for footwear and tire impression capture

The forensic science community raised the need for improved evidence recognition, collection, and visualization analytical instrumentation for field and laboratory use. While the 3D optical techniques for imaging static objects have been extensively studied, there is still a major gap between current knowledge and collecting high‐quality footwear and tire impression evidence. Among optical means for 3D imaging, digital fringe projection (DFP) techniques reconstruct 3D shape from phase information, achieving camera‐pixel spatial resolution. This paper presents a high‐resolution 3D imaging technology using DFP techniques dedicated to footwear and tire impression capture. We developed fully automated software algorithms and a graphical user interface (GUI) that allow anyone without training to operate for high‐quality 3D data capture. We performed accuracy evaluations and comparisons comparing with the commercial high‐end 3D scanner and carried out qualitative tests for various impressions comparing with the current practices. Overall, our technology achieves similar levels of accuracy and resolution with a high‐end commercially available 3D scanner, while having the merits of being (1) more affordable; (2) much easier to operate; and (3) more robust. Compared with the current practice of casting, our technology demonstrates its superiority because it (1) is non‐destructive; (2) collects more evidence detail than casts, especially when an impression is fragile; (3) requires less time and money to collect each piece of evidence; and (4) results in a digital file that can easily be shared with other examiners.     

坚持以人民为中心推进全球人权进步--在联合国人权理事会第46届会议高级别会议上的讲话

主席女士,各位同事:很高兴代表中国政府向联合国人权理事会第46届会议致辞。人类正在同新冠肺炎疫情进行艰苦卓绝的斗争。病毒是我们共同的敌人,战胜疫情是我们承担的使命,团结合作是我们唯一的选择。这场世纪大流行给全人类带来巨大灾难。1亿多人染疫,200多万生命消逝,1.3亿人口返贫。全球不平等加剧,南北差距拉大,发展权受到新的挑战。     

在外交部2020年新年招待会上的致辞

Your Excellency former State Councilor Dai Bingguo,Your Excellencies ambassadors,members of the diplomatic corps,representatives of international oi^anizations and spouses,Ladies and gentlemen,Friends,Good evening!It gives me great pleasure to gather with our distinguished guests here to renew friendship and ring in the new year.On behalf of the Chinese Foreign Ministry,let me extend a warm welcome to all the ambassadors,representatives and members of the diplomatic corps who have joined our reception this evening.     

清末民国检察文书的转型与司法现代化——基于司法档案的考察

清末以降的检察制度整体而言处在不断变革和进步之中,其文书的变化尤为明显,作为官方记录反映出司法现代化的进程。在检察制度建立之初,中国传统司法审判中最重要文书之一的批词被适用为主要的检察文书以为过渡,相应的起诉文书也初现雏形;南京国民政府时期,批词转变为近代化的规范文本,起诉书、上诉书现代化成型,其格式、内容也不断适应中央层面的现代化的改革需求,在短短二三十年间经历了从传统到现代的转型。然而形式上的检察文书快速转型与实际检察运作不一致的现象也凸显出近代中国在司法现代化过程中的根本性矛盾。