Distribution of dimethoate in the body after a fatal organphosphateintoxication

Many organophosphate pesticides (OPs) such as dimethoate are used to eradicate household pests, and those occurring in agriculture and forestry sectors. Combinations of two or more different insecticides have been manufactured to increase their effectiveness. A case of death is presented as suspected organophosphates intoxication. Autopsy was unremarkable except for grayish fluid in the stomach, with garlicky odor. A systematic toxicological analysis on post-mortem specimens revealed high concentrations of dimethoate in blood 38 μg/mL, urine 0.47 μg/mL, brain 2.2 μg/g, myocardial muscle 7.6 μg/g, liver 4.6 μg/g, lung 7.6 μg/g, skeletal muscle 21 μg/g, kidney 55 μg/g and gall bladder 31 μg/g. Blood alcohol was 2.85 g/L, cyclohexanone and cyclohexanol were also detected in the blood but not quantified. The cause of death was determined as organophosphate intoxication.     

Residence patterns of the elderly in early eighteenth-century Iceland

In this article the 1703 Icelandic census is used to shed light on the living arrangements of the elderly during a period of harsh climatic and social conditions. The census is unique in the sense that it includes an entire population of a country at an early date. It was taken on the initiative of the authorities in Denmark with the objective of examining the dire conditions of the Icelandic population and, in particular, assessing the number of paupers and vagrants. The census therefore provides interesting possibilities to analyse the situation of the most vulnerable groups of the society. In a society with low nuptiality rates and a low sex ratio, the risk of becoming dependent on poor relief increased with age. Elderly persons who were not able to retire in the household of an offspring ran the risk of spending their last years as paupers. In the 75 and older age group, no less than 43.5% of women were in the position of a pauper. In line with other recent studies on intergenerational co-residence, this study indicates that the elderly preferred to co-reside with their offspring. Even though elderly couples preferred to remain in the position of head of household, most would co-reside with their children. As regards widowed persons, there were noticeable differences between elderly men and women. Elderly widows were thus more likely than widowers to resign from headship on entering widowhood in order to retire in the household of one of an offspring.     

Differentiation of regioisomeric ring-substituted fluorophenethylamines with product ion spectrometry

The electron ionization (EI) of aromatic ring-substituted isomers gives virtual identical mass spectra which seriously affects their analysis. Especially regioisomeric meta- and para-ring-substituted compounds cannot show any ortho-effect reactions making their differentiation by mass spectrometry impossible. Furthermore o-, m- and p-substituted compounds can only be separated insufficiently by chromatography due to their very similar retention that do not allow univocal identification. Product ion mass spectrometry has proved to be a useful tool to differentiate structurally closely related fluorophenethylamines even in the case of the meta- and para-isomers. A series of N-alkylated o-, m- and p-fluoroamphetamines and 1-(4-fluorophenyl)butan-2-amines have been synthesized in microscale and studied by product ion spectrometry. The combination of chemical ionization (CI) and product ion spectrometry of hydrogen fluoride loss ions [M+H?HF]⁺ allows a univocal differentiation of all studied fluoro-substituted phenethylamines without prior derivatization. This method with submicrogram detection limits provides great advantages for the differentiation between aromatic regioisomeric fluorophenethylamine designer drugs where other methods such as nuclear magnetic resonance (NMR) spectrometry lack sufficient sensitivity or might fail because complex mixtures have to be analyzed.     

FBI analysis of terrorist incidents in the United States — 1982

Abstract

When analyzing terrorism in Germany, attention normally focuses on the Rote Armee Fraktion, better known as Baader‐Meinhof gang. Already in the early years of the RAF there existed different groups, such as the Movement 2nd June, which often rivaled and strongly critized the elitist avant‐gardism of Andreas Baader, Ulrike Meinhof, and Gudrun Ensslin. Today only a small fragment of the some 350 terrorist acts and 500 acts of sabotage (1985 statistics) can be attributed to the RAF. Germany's other terrorists, the Revolutionary Cells and autonomous/anti‐imperialist groups have long ago outdone the RAF and become a much graver threat to the internal security of the Federal Republic. Though similarities in rhetoric and operational approach exist between the RAF and these groups, the existing underlying differences are strong and until recently have prevented cooperation. The hunger strike campaign of the winter 1984/1985 appears to present a change in policies on behalf of the Cells.