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Mathias Albert 《Global Society》2001,15(1):107-109
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The forensic toxicology community has recognized flunitrazepam and its metabolite (7-aminoflunitrazepam) as compounds of concern for several years. In this procedure, the analytes were extracted from whole blood and urine onto single mode solid phase cartridges (butyl) using nitrazepam as an internal standard. The columns were washed with distilled water and hexane. All three compounds were eluted from the sorbent using an ethyl acetate-methanol solvent mixture. After collection and evaporation of the solvent, the residue was dissolved in A, 0.1% (v/v) aqueous trifluoroacetic acid for HPLC-PDA analysis or B, ethyl acetate for derivatization with pentafluoropropionic anhydride (PFPA) for analysis by gas chromatography-mass spectrometry (selected ion monitoring, SIM). A limit of quantitation for this method using HPLC-PDA was found to be 5 and 1.0 ng mL(-1) by SIM. 相似文献
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Geller JL Fisher WH Grudzinskas AJ Clayfield JC Lawlor T 《International journal of law and psychiatry》2006,29(6):551-562
In American jurisprudence, two justifications have traditionally been put forth to support the government's social control of persons with mental illness: police power and parens patriae. As public mental hospitals became less available as loci in which to exercise these functions, governments sought alternative means to achieve the same ends. One prominent but quite controversial means is involuntary outpatient treatment (IOT). While the concerns about IOT have been myriad, one often alluded to but never documented is that of "net-widening." That is, once IOT became available, it would be applied to an ever greater number of individuals, progressively expanding the margins of the designated population to whom it is applied, despite the formal standard for its application remaining constant. We tested the net-widening belief in a naturalistic experiment in Massachusetts. We found that net-widening did not occur, despite an environment strongly conducive to that expansion. At this time, whatever the arguments against IOT might be, net-widening should not be one of them. 相似文献
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Information,intelligence, enlightened public policy: Functions and organization of societal feedback
Albert D. Biderman 《Policy Sciences》1970,1(1):217-230
Normative properties which make social statistics useful as social indicators are illuminated by considering the functions systematic social knowledge has at various levels of social organization and the involvements of actors at these various levels in roles which result in such knowledge. Modes and degrees of generalization which make knowledge useful for action at the lowest levels of social organization (information) or for administration at intermediate bureaucratic levels (intelligence) are not necessarily applicable to the formation of broad social policy (policy knowledge) or for affecting the general conceptions of the social world held by broad public (enlightenment). The latter two functions are not always well served by data which have been collected and ordered by systems primarily responsive to the former two functions.Portions of this paper were presented at the 65th Annual Meeting of the American Political Science Association, New York City, 6 September 1969 and at a Colloquium on Urban Intelligence Systems at the Center for Urban Studies, Wayne State University, 17 April, 1969. 相似文献