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11.
Alex J. Krotulski M.S.F.S. Susan Jansen Varnum Ph.D. Barry K. Logan Ph.D. 《Journal of forensic sciences》2020,65(2):550-562
Novel psychoactive substances (NPS) are synthetic drugs that pose serious public health and safety concerns. A multitude of NPS have been identified in the United States, often implicated in forensic investigations. The most common and effective manner for identifying NPS is by use of mass spectrometry and the true utility lies within nontargeted acquisition techniques. During this study, a liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) assay was developed, validated, and implemented for forensic toxicology testing. A SCIEX TripleTOF™ 5600 + with SWATH® acquisition was used. Resulting data were compared against an extensive library database containing more than 800 compounds. The LC-QTOF-MS assay was applied to the reanalysis of biological sample extracts to discover emergent NPS. More than 3,000 sample extracts were analyzed, and more than 20 emerging NPS were detected for the first time. Among these were isopropyl-U-47700, 3,4-methylenedioxy-U-47700, fluorofuranylfentanyl, N-methyl norfentanyl, 2F-deschloroketamine, 3,4-methylenedioxy-alpha-PHP, eutylone, and N-ethyl hexedrone. 相似文献
12.
The private nature of corporate actors does not necessarily preclude them from contributing to public interest. When business strategies and genuine public motivation are favorably aligned, corporate actors from the private sector can also drive public sector innovations. For a private corporation, policy entrepreneurship inherently entails crossing not only the public–private boundary but also various policy domains. This study formulates five propositions to characterize the cross-boundary strategies of corporate policy entrepreneurship, a distinct form of policy entrepreneurship in a developing authoritarian state. The case study of mobile healthcare payment innovation in China finds that the corporate entrepreneur used a series of cross-boundary strategies adeptly that eventually made the innovation not only adopted in one locality but also rapidly diffused nationwide. These strategies were not used in isolation or in a pure stepwise fashion but appeared to be recursive and interactive, suggesting the dynamic nature of corporate policy entrepreneurship in a multilevel governance system. More studies could be done to further examine strategies and processes of other forms of policy entrepreneurship in various national and sectoral settings. 相似文献
13.
Nicole Leeper Piquero Kristan Fox Alex R. Piquero George Capowich Paul Mazerolle 《Journal of youth and adolescence》2010,39(4):380-392
Much of the prior work on General Strain Theory (GST) has focused on how strain and negative emotions interrelate to produce
criminal—especially violent—activity. Very little research has extended GST to examine other types of non-criminal, negative
behavior, such as self-harming behaviors associated with disordered eating, a traditionally female-specific self-directed
outcome. Using a sample of 338 young adults (54% female, 95% white), this article applies GST to disordered eating by examining
how strain and negative emotions relate to this particular outcome across gender. Findings indicate that two types of strain
measures predict depressive symptoms among males and females, that inequitable strainful experiences relate to disordered
eating among females but not males, that depressive symptoms but not anger increase disordered eating for both males and females,
and that membership in Greek organizations (sororities or fraternities) is associated with disordered eating but only for
males. Implications for theory and directions for future research are highlighted. 相似文献
14.
This study examined the mediated and moderated effects of a universal family-focused preventive intervention, delivered during young adolescence, on internalizing symptoms assessed in young adulthood. Sixth grade students (N=446; 52% female; 98% White) and their families from 22 rural Midwestern school districts were randomly assigned to the experimental conditions in 1993. Self-report questionnaires were administered at seven time points (pre-test to young adulthood-age 21) to those receiving the Iowa Strengthening Families Program (ISFP) and to the control group. Results showed that growth factors of adolescent internalizing symptoms (grades 6-12) were predicted by ISFP condition and risk status (defined as early substance initiation). Moderation of the condition effect by risk status was found, with higher-risk adolescents benefitting more from the ISFP. Results also supported the hypothesis that the ISFP's effect on internalizing symptoms in young adulthood was mediated through growth factors of adolescents' internalizing symptoms; risk moderation, however, was only marginally significant in young adulthood. The relative reduction rate on clinical or subclinical levels of young adult internalizing symptoms was 28%, indicating that for every 100 young adults displaying clinical or subclinical levels of internalizing symptoms from school districts not offering an intervention, there could be as few as 72 displaying those levels of symptoms in school districts that offered middle school prevention programming. These findings highlight how the positive effects of family-focused universal interventions can extend to non-targeted outcomes and the related potential public-health impact of scaling up these interventions. 相似文献
15.
Research has linked the role of education to delinquency, but much of the focus has been on general population samples and
with little attention to demographic differences. Employing a cumulative disadvantage framework that integrates elements of
informal social control and labeling theories, this article examines whether academic achievement serves as a positive turning
point and re-directs juvenile delinquents away from subsequent offending. Attention is also given to race/sex contingencies.
Using a sample of 4,147 delinquents released from Florida correctional institutions (86% male, 57% non-White, average age
at release = 16.8 years), propensity score analysis yielded two findings: youth with above average academic achievement while
incarcerated were significantly more likely to return to school post-release, and youth with above average attendance in public
school were significantly less likely to be re-arrested in the 1-year post-release period. While the academic gains were pronounced
among African-American males, the preventive effects of school attendance are similar across race and sex, suggesting that
education can be a part of a larger prevention effort that assists juvenile delinquents in successful community re-entry. 相似文献
16.
M. Alex Wagaman Jama Shelton Rebecca Carter Kado Stewart Stacey Jay Cavaliere 《Child & Youth Services》2019,40(1):43-64
As transgender and gender-expansive (TGE) youth and young adults (YYA) navigate challenging environments, they often seek spaces for safety and acceptance. This study explores ways in which a group of TGE YYA who were engaged with a community-based service organization make sense of their experiences, challenges, and successes in ways that illuminate the factors and processes associated with resilience. Secondary data analysis was conducted on qualitative responses from 85 TGE YYA ages 13–24. The themes that emerged provide insight into the ways community-based programs and providers can understand and support the resilience of TGE YYA. 相似文献
17.
Alex R. Piquero 《Society》2018,55(3):237-242
This articles uses the work of Pyrooz and Densley as a springboard for a larger discussion of race-based perceptions from gangs to criminals to athletes. It concludes by showcasing how perceptions do not always equate with reality and the consequences of doing so. 相似文献
18.
The politicization of government communications requires intense control. Centralization of government power accompanies advances in information and communications technology, as political elites use branding strategy in an attempt to impose discipline on their messengers and on media coverage. The strategic appeal of public sector branding is that it replaces conflicting messages with penetrating message reinforcement. Among the notable features are central control, a marketing ethos, a master brand, communications cohesiveness, and message simplicity. Together these features work to conflate the party government and the public service, which perpetuates trends of centralization. Using Canada's Conservative government (2006–2015) as a case study, public sector branding explains the hyper control over government communications and demonstrates why these developments can be expected to last, regardless of which party or leader is in control. 相似文献
19.
20.
Alex Ingrams 《Local Government Studies》2017,43(3):364-387
Public organisations are often described as being subject to types of complexity that result from the interorganisational structure of governance networks. Transparency programmes add another level of complexity due to increased information openness. However, neither the nature of this complexity nor the network management approaches needed for transparency programmes has been conceptually developed. To address this gap, this article brings together governance complexity theory and knowledge management theory. An empirical model is tested using the case of police open data with regression analysis and 22 expert interviews. The results show that institutional and environmental complexity such as budget pressures, legal-normative constraints, and task complexity exert a negative influence on police information openness. However, network knowledge management practices including developing mission focus on people and communication and overcoming organisational boundaries through interorganisational collaboration can counteract these problems of complexity. 相似文献