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41.
Levelling Up?     
‘Levelling up’ is the new UK government mantra to describe its ambitions for addressing longstanding local and regional inequalities and, especially, for tackling the problems of ‘left-behind’ places. This article examines the thinking behind this slogan and the associated policy agenda. We identify a danger of misdiagnosis leading to policies that do little to ameliorate conditions in the places that most need help. The government’s agenda appears, so far, to be driven by electoral calculation rather than a real engagement with tackling deep inequalities.  相似文献   
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The use of quantum dots (QDs) in the area of fingermark detection is currently receiving a lot of attention in the forensic literature. Most of the research efforts have been devoted to cadmium telluride (CdTe) quantum dots often applied as powders to the surfaces of interests.Both the use of cadmium and the nano size of these particles raise important issues in terms of health and safety. This paper proposes to replace CdTe QDs by zinc sulphide QDs doped with copper (ZnS:Cu) to address these issues. Zinc sulphide–copper doped QDs were successfully synthesized, characterized in terms of size and optical properties and optimized to be applied for the detection of impressions left in blood, where CdTe QDs proved to be efficient. Effectiveness of detection was assessed in comparison with CdTe QDs and Acid Yellow 7 (AY7, an effective blood reagent), using two series of depletive blood fingermarks from four donors prepared on four non-porous substrates, i.e. glass, transparent polypropylene, black polyethylene and aluminium foil. The marks were cut in half and processed separately with both reagents, leading to two comparison series (ZnS:Cu vs. CdTe, and ZnS:Cu vs. AY7). ZnS:Cu proved to be better than AY7 and at least as efficient as CdTe on most substrates. Consequently, copper-doped ZnS QDs constitute a valid substitute for cadmium-based QDs to detect blood marks on non-porous substrates and offer a safer alternative for routine use.  相似文献   
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This article examines the reform of the health care system in England in terms of the risk assessment and risk management. Three major health policies are examined, the Health of the Nation strategy, community care and the Patient's Charter. The article demonstrates that effective risk assessment and risk management is an important component of each initiative. The Health of the Nation strategy is based on epidemiological evidence on the nature of health risks and is linked to specific targets for the reduction of harm that require effective management of risks. Community care is a well established policy designed to provide long term and continuing support for vulnerable individuals in the community. With high profile incidents in the 1980s, there has been a greater emphasis on effective risk assessment and risk management, especially to protect the public. The Patient's Charter is designed to empower users of service.

Central to this strategy is informed consent. Effective empowerment depends of the provision of adequate information, especially on the risks of treatment. Although competent adults may formally be autonomous risk-taking decision-makers, their ability to assess risk and make decisions depends on having adequate information.  相似文献   
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Among the numerous methods dedicated to the detection of latent fingermarks, the MultiMetal Deposition (MMD) offers, as a main advantage, the ability to be applied on a great number of porous and non-porous surfaces, e.g., paper, plastic, glass, latex, and polystyrene, even if wetted. While considered as a powerful and sensitive technique, MMD is often neglected, mainly because of operational limitations (siliconized vessels, restrictive pH domain, numerous immersion baths, ...). In this contribution, we propose a modification of the standard MMD method so that the procedure is simplified with a number of baths reduced to a minimum. To reach this goal, it was necessary to obtain a fully operable solution which could detect fingermarks in a single step. We chose to take advantage of the molecular recognition mechanisms by functionalizing the gold nanoparticles with a molecular host able to bind itself to gold while keeping the ability to trap molecules in solution. Cyclodextrins were chosen as they can be easily chemically modified to offer gold-binding abilities. Moreover, they are widely used as hosts for various molecular guests (dyes, luminescent molecules, ...). This new formulation has been tested on three different surfaces to attest the feasibility of this strategy. Successful results were obtained with detailed fingermarks offering a good contrast to allow their identification without the need to enhance the results (such as with a physical developer). If the new formulation behaves very similarly to the old one, in terms of experimental conditions, it offers the additional advantage to develop fingermarks after immersing them in only one bath. The goal is thus reached.  相似文献   
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This study examines the role that masculinity plays in men’s decisions to participate in bar fights. The data were obtained via semi-structured interviews with adult, White males in Louisiana who had a history of fighting. We argue that specific elements of fighting events represent symbolic attempts at attaining and maintaining honor and status, which many men in working class culture equate with masculine identity. While winning fights was seen as important, participants suggest that willingness to fight in the right circumstances builds character, develops an honorable reputation, and prevents negative labels. We further argue that pursuit of symbolic masculinity is important to working class men, who possess fewer alternative avenues for achieving status than do those from higher social ranks.  相似文献   
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