STR data for the AmpFlSTR SGM Plus loci from Warmia and Mazury (NE Poland)

Allele frequencies for the ten STRs included in the AmpFlSTR SGM Plus kit were determined in a sample of 320 unrelated individuals born in the region of Warmia and Mazury (NE Poland). All loci met Hardy-Weinberg expectations. Exact tests disequilibrium analysis revealed only one departure from independence out of 45 pair-wise comparisons of the 10 loci.     

Quantitative structure–activity relationship (QSAR) methodology in forensic toxicology: Modeling postmortem redistribution of structurally diverse drugs using multivariate statistics

Postmortem redistribution (PMR) constitutes a multifaceted process, which renders the analytical results of drug concentrations inaccurate to be interpreted by forensic toxicologists. The aim of the present study was to evaluate whether quantitative structure–activity relationship (QSAR) methodology could serve as an effective tool to estimate the ability of drugs to redistribute across tissue barriers during postmortem period on the basis of their molecular, physicochemical and structural properties. In this aspect, multivariate data analysis (MVDA) was applied to a set of 77 structurally diverse drugs. PMR data expressed by the central:peripheral concentration ratio (C:P ratio) was taken from the literature. An adequate and robust QSAR model (R² = 0.65, Q² = 0.56, RMSEE = 0.34) was established for 59 (77%) out of 77 drugs. Although the derived QSAR model presented limited applicability, it provided an informative illustration of the contributing molecular, physicochemical and structural properties in PMR process. Drugs with strong basic properties and enhanced molecular size, flexibility, lipophilicity and number of halogens were found to be susceptible to increased PMR. Due to the high complexity of PMR process, further QSAR studies need to focus on structurally related drugs to develop more specific models, which could serve as alternative tools to evaluate PMR for different chemical classes.     

Reasons underlying treatment preference: an exploratory study

Very little is known about what factors influence women's treatment preferences after a sexual assault. To learn more about these factors, data were collected from 273 women who read a standard "if this happened to you, what would you do" scenario describing a sexual assault and subsequent trauma-related psychiatric symptoms. After reading standardized treatment options for a pharmacotherapy (sertraline) and a psychotherapy (cognitive behavioral treatment), participants made a hypothetical treatment choice and reported the main reasons for their choice. Women often cited reasons surrounding the effectiveness of a treatment as the primary reason for their treatment preference, suggesting potential masking of symptoms with the medication and more logical, long-lasting effects with the psychotherapy. Other common reasons underlying treatment preference were wariness of the medication and positive feelings about talking in psychotherapy. Better understanding factors that influence treatment preference may aid in refining psychoeducation materials regarding the psychological consequences of sexual assault and their treatment for the lay public and in helping clinicians further tailor their discussion of treatment alternatives for these women.     

Indispensable,yet Invisible: Drinking water management as a local political issue in Swedish municipalities

ABSTRACT

Local policy-makers’ incentives to address an issue is conditioned by how they perceive public attention. Our study focuses on drinking water management at the municipal level in Sweden. Provisioning and management of drinking water is a responsibility of the local governments. Interviews with local politicians and public administrators in seven municipalities reveal that local policy-makers think that citizens view provisioning of drinking water as a taken for granted service, and also lack knowledge of and interest in drinking water issues. Public attention is further seen as a double-edged sword since engagement in water issues often is a result of problems with water provision. The findings are discussed from a theoretical perspective of the role of agenda-setting in public policy. It is argued that the view of policy-makers of citizens as unengaged negatively affects the incentives to bring drinking water to a prominent place on the local policy agenda.     

The Armenians of Los Angeles: Rethinking “Americanization”

Abstract

The existing scholarship typically measures “Americanization” along structural lines—such as knowledge of public policies, percentage of life spent in the U.S., or proficiency in the English language. While these variables are certainly important, they overlook another important dimension of newcomers’ post-migration experiences—namely, immigrants’ psychological attachment and sense of belonging to the American social, political, and economic fabric. This article therefore reevaluates what it means to Americanize by exploring the psychological (or symbolic) dimensions of multigenerational immigrants’ evolving political beliefs toward the polity. In rethinking the process of Americanization, we rely on a largely understudied immigrant population—that is, the Los Angeles Armenians (or Armenian Angelenos)—and an original public opinion survey—the Armenian Angeleno Survey (AAS). This study demonstrates that symbolic (rather than merely structural) Americanization is a useful framework in studying how contemporary immigrant groups position themselves in relation to the polity and understand important political outcomes. This article thus introduces an expanded model based on how multigenerational immigrants cultivate their ethnic communities while becoming ideological members of American society.     

Reply to my critics

ABSTRACT

This paper offers an overview of the central argument of my book, Territorial Sovereignty, and replies to four critics.