Post-mortem cases involving amphetamine-based drugs in The Netherlands. Comparison with driving under the influence cases

In this study we reviewed the post-mortem cases in the years 1999-2004 that were presented at the Netherlands Forensic Institute. The concentrations of amphetamine-based drugs in femoral blood from cases of suspected unnatural death were compared with concentrations in whole blood from non-fatal cases of driving under the influence (DUI cases) and with literature. Furthermore, the combinations with other drugs and/or alcohol were investigated. Amphetamine-based drugs were present in 70 post-mortem cases and 467 DUI cases. The most detected amphetamine-based drug was MDMA, followed by amphetamine. The presence of MDA could usually be explained by metabolism of MDMA. Methamphetamine and MDEA were rarely present. Frequently, the amphetamine-based drugs were taken in combination with alcohol and/or other non-amphetamine-based drugs such as cocaine or cannabinoids. The 70 post-mortem cases were divided into 38 amphetamine-based drug caused (i.e. the amphetamine-based drug directly caused or contributed to the death) and 32 amphetamine-based drug related deaths (i.e. death was not directly caused by the amphetamine-based drug). In the latter category, other (poly)drug intoxications and death by violence or drowning were the most frequent causes of death. In 30 cases, MDMA caused death directly. The range in blood concentrations of MDMA in these cases was substantial, i.e. 0.41-84 mg/L with a median concentration of 3.7 mg/L (n=30). MDMA blood concentrations in the MDMA related deaths (n=20) and in the DUI cases (n=360) varied up to 3.7 and 4.0 mg/L, respectively. Seven victims died from the direct effects of amphetamine; the blood concentration of amphetamine ranged from 0.24 to 11.3 mg/L, with a median concentration of 1.7 mg/L (n=7). The median concentrations of amphetamine in the amphetamine related deaths (n=13) and the DUI cases (n=208) were much lower, i.e. 0.28 and 0.22 mg/L, respectively. Amphetamine blood concentrations up to 6.0 and 2.3 mg/L were seen in the drug related deaths and DUI cases, respectively. The most frequently encountered amphetamine-based drugs in the investigated deaths were MDMA and amphetamine. The majority of MDMA- and amphetamine-caused deaths, i.e. 90% of these deaths, occurred with blood concentrations above 1.5 and 0.80 mg/L, respectively. MDMA and amphetamine blood concentrations in drug related deaths and DUI cases, however, overlap the range of fatal concentrations. Therefore, MDMA or amphetamine concentrations should never be used alone to establish the cause of death.     

Post-mortem cases involving amphetamine-based drugs in the Netherlands: Comparison with driving under the influence cases

In this study we reviewed the post-mortem cases in the years 1999–2004 that were presented at the Netherlands Forensic Institute. The concentrations of amphetamine-based drugs in femoral blood from cases of suspected unnatural death were compared with concentrations in whole blood from non-fatal cases of driving under the influence (DUI cases) and with literature. Furthermore, the combinations with other drugs and/or alcohol were investigated. Amphetamine-based drugs were present in 70 post-mortem cases and 467 DUI cases. The most detected amphetamine-based drug was MDMA, followed by amphetamine. The presence of MDA could usually be explained by metabolism of MDMA. Methamphetamine and MDEA were rarely present. Frequently, the amphetamine-based drugs were taken in combination with alcohol and/or other non-amphetamine-based drugs such as cocaine or cannabinoids. The 70 post-mortem cases were divided into 38 amphetamine-based drug caused (i.e. the amphetamine-based drug directly caused or contributed to the death) and 32 amphetamine-based drug related deaths (i.e. death was not directly caused by the amphetamine-based drug). In the latter category, other (poly)drug intoxications and death by violence or drowning were the most frequent causes of death.In 30 cases, MDMA caused death directly. The range in blood concentrations of MDMA in these cases was substantial, i.e. 0.41–84 mg/L with a median concentration of 3.7 mg/L (n = 30). MDMA blood concentrations in the MDMA related deaths (n = 20) and in the DUI cases (n = 360) varied up to 3.7 and 4.0 mg/L, respectively. Seven victims died from the direct effects of amphetamine; the blood concentration of amphetamine ranged from 0.24 to 11.3 mg/L, with a median concentration of 1.7 mg/L (n = 7). The median concentrations of amphetamine in the amphetamine related deaths (n = 13) and the DUI cases (n = 208) were much lower, i.e. 0.28 and 0.22 mg/L, respectively. Amphetamine blood concentrations up to 6.0 and 2.3 mg/L were seen in the drug related deaths and DUI cases, respectively. The most frequently encountered amphetamine-based drugs in the investigated deaths were MDMA and amphetamine. The majority of MDMA- and amphetamine-caused deaths, i.e. 90% of these deaths, occurred with blood concentrations above 1.5 and 0.80 mg/L, respectively. MDMA and amphetamine blood concentrations in drug related deaths and DUI cases, however, overlap the range of fatal concentrations. Therefore, MDMA or amphetamine concentrations should never be used alone to establish the cause of death.     

‘Can’t We Discuss This?’ Liberalism and the Challenge of Islam in the Netherlands

The Netherlands, which has seen the political murders of the populist Pim Fortuyn in 2002 and film director Theo van Gogh in 2004, faces particular challenges in meeting Europe's “Islamic problem.” Not just a welfare state like all European countries, the Netherlands also has its own peculiar “pillarization” social structure, which developed in order to permit all groups to be different but equal. For decades, the differences were among various groups of Christians and secularized Christians. But after the 1968 protest movement, and with an influx of immigrants, parallel societies emerged in which Muslims could build up their own institutions and values. While the system has clearly failed, the responses of the Dutch political class to date seem inadequate. This article outlines an approach to the challenge of European Islam that could restore political life to the right priorities.     

Does Stimulating Physical Activity Affect School Performance?

This paper investigates whether encouraging children to become more physically active in their everyday life affects their primary school performance. We use data from a field quasi-experiment called the Active Living Program, which aimed to increase active modes of transportation to school and active play among 8- to 12-year-olds living in low socioeconomic status (SES) areas in the Netherlands. Difference-in-differences estimations reveal that while the interventions increase time spent on physical activity during school hours, they negatively affect school performance, especially among the worst-performing students. Further analyses reveal that increased restlessness during instruction time is a potential mechanism for this negative effect. Our results suggest that the commonly found positive effects of exercising or participating in sports on educational outcomes may not be generalizable to physical activity in everyday life. Policymakers and educators who seek to increase physical activity in everyday life need to weigh the health and well-being benefits against the probability of increasing inequality in school performance.     

A new approach to the right to privacy,or how the European Court of Human Rights embraced the non-domination principle

As it is currently regulated, the right to privacy is predominantly conceived as a subjective right protecting the individual interests of natural persons. In order to determine whether this right has been affected in a specific situation, the so-called ‘non-interference’ principle is applied. Using this concept, it follows that the right to privacy is undermined if an ‘infringement’ with that right by a third party can be demonstrated. Although the ‘infringement’-criterion works well when applied to more traditional privacy violations, such as a third party entering the home of an individual or eavesdropping on a private conversation, with respect to modern data-driven technologies, it is often very difficult to demonstrate an actual and concrete ‘infringement’ on a person's right or freedom. Therefore, an increasing number of privacy scholars advocate the use of another principle, namely the republican idea of ‘non-domination’. At the core of this principle is not the question of whether there has been an ‘interference’ with a right; rather, it looks at existing power relations and the potential for the abuse of power. Interestingly, in recent times, the European Court of Human Rights seems to accept the republican approach to privacy when it deals with complex data-driven cases.     

The socialization potential of the CDM in EU–China climate relations

This article hypothesizes that the material incentives associated with the clean development mechanism (CDM) have contributed to the internalization of climate protection norms in China. In current academic research, the CDM has both been extolled as a cost-effective and vilified as an environmentally and ethically inadequate climate mitigation instrument. Few studies so far, however, have looked into the CDM’s potential contribution to socialization-related phenomena such as raising climate change awareness in emerging economies. The relationship with the EU is highly relevant in this context, as the emission reduction credits (CERs) resulting from CDM projects would not have had any meaningful prices without the European Union’s Emissions Trading System (EU ETS). This article aims to fill the current research gap by studying the socialization potential of the CDM in EU–China climate relations in four periods, namely initiation (2001–2005), improvement (2005–2007), consolidation (2008–2010) and habit formation (2010–2014). We argue that there is at least a discernible effect and that the underlying causal mechanism involves the emergence and activities of norm entrepreneurs and habit formation through a process of legal institutionalization.     

A new approach to measuring technology with an application to the shape of the diffusion curves

This paper documents the sources and measures of the cross-country historical adoption technology (CHAT) data set that covers the diffusion of about 115 technologies in over 150 countries over the last 200 years. We use this comprehensive data set to explore the shape of the diffusion curves. Our main finding is that, once the intensive margin is measured, technologies do not diffuse in a logistic way.